Optimization of enzymatic biodiesel synthesis using RSM in high pressure carbon dioxide and its scale up

Myunggu Lee; Dohoon Lee; Jaehoon Cho; Junhac Lee; Sangyong Kim; Seung Wook Kim; Chulhwan Park

doi:10.1007/s00449-013-0903-9

Optimization of enzymatic biodiesel synthesis using RSM in high pressure carbon dioxide and its scale up

Myunggu Lee, Dohoon Lee, Jaehoon Cho, Junhac Lee, Sangyong Kim, Seung Wook Kim, Chulhwan Park

Department of Chemical and Biological Engineering

Research output: Contribution to journal › Article

4 Citations (Scopus)

Abstract

Enzymatic synthesis of biodiesel by the transesterification of canola oil and methanol in high pressure carbon dioxide [HPCO₂: near-critical and supercritical carbon dioxide (NcCO₂ and ScCO₂)] was optimized using response surface methodology (RSM). RSM based on 5-level-5-factor central composite rotatable design (CCRD) was used to evaluate the effects of temperature, pressure, enzyme loading, substrate molar ratio, and time on the conversion to biodiesel by transesterification. Finally, batch reactions for biodiesel synthesis were preformed in a 100 mL and 7 L high-pressure stirred batch reactors.

Original language	English
Pages (from-to)	775-780
Number of pages	6
Journal	Bioprocess and Biosystems Engineering
Volume	36
Issue number	6
DOIs	https://doi.org/10.1007/s00449-013-0903-9
Publication status	Published - 2013 Jun

Keywords

High pressure carbon dioxide
Lipase
Optimization
Response surface methodology
Transesterification

ASJC Scopus subject areas

Biotechnology
Bioengineering

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10.1007/s00449-013-0903-9

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Lee, M., Lee, D., Cho, J., Lee, J., Kim, S., Kim, S. W., & Park, C. (2013). Optimization of enzymatic biodiesel synthesis using RSM in high pressure carbon dioxide and its scale up. Bioprocess and Biosystems Engineering, 36(6), 775-780. https://doi.org/10.1007/s00449-013-0903-9

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abstract = "Enzymatic synthesis of biodiesel by the transesterification of canola oil and methanol in high pressure carbon dioxide [HPCO2: near-critical and supercritical carbon dioxide (NcCO2 and ScCO2)] was optimized using response surface methodology (RSM). RSM based on 5-level-5-factor central composite rotatable design (CCRD) was used to evaluate the effects of temperature, pressure, enzyme loading, substrate molar ratio, and time on the conversion to biodiesel by transesterification. Finally, batch reactions for biodiesel synthesis were preformed in a 100 mL and 7 L high-pressure stirred batch reactors.",

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AU - Kim, Seung Wook

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