TY - JOUR
T1 - Optimization of enzymatic biodiesel synthesis using RSM in high pressure carbon dioxide and its scale up
AU - Lee, Myunggu
AU - Lee, Dohoon
AU - Cho, Jaehoon
AU - Lee, Junhac
AU - Kim, Sangyong
AU - Kim, Seung Wook
AU - Park, Chulhwan
PY - 2013/6
Y1 - 2013/6
N2 - Enzymatic synthesis of biodiesel by the transesterification of canola oil and methanol in high pressure carbon dioxide [HPCO2: near-critical and supercritical carbon dioxide (NcCO2 and ScCO2)] was optimized using response surface methodology (RSM). RSM based on 5-level-5-factor central composite rotatable design (CCRD) was used to evaluate the effects of temperature, pressure, enzyme loading, substrate molar ratio, and time on the conversion to biodiesel by transesterification. Finally, batch reactions for biodiesel synthesis were preformed in a 100 mL and 7 L high-pressure stirred batch reactors.
AB - Enzymatic synthesis of biodiesel by the transesterification of canola oil and methanol in high pressure carbon dioxide [HPCO2: near-critical and supercritical carbon dioxide (NcCO2 and ScCO2)] was optimized using response surface methodology (RSM). RSM based on 5-level-5-factor central composite rotatable design (CCRD) was used to evaluate the effects of temperature, pressure, enzyme loading, substrate molar ratio, and time on the conversion to biodiesel by transesterification. Finally, batch reactions for biodiesel synthesis were preformed in a 100 mL and 7 L high-pressure stirred batch reactors.
KW - High pressure carbon dioxide
KW - Lipase
KW - Optimization
KW - Response surface methodology
KW - Transesterification
UR - http://www.scopus.com/inward/record.url?scp=84878759332&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84878759332&partnerID=8YFLogxK
U2 - 10.1007/s00449-013-0903-9
DO - 10.1007/s00449-013-0903-9
M3 - Article
C2 - 23423556
AN - SCOPUS:84878759332
VL - 36
SP - 775
EP - 780
JO - Bioprocess and Biosystems Engineering
JF - Bioprocess and Biosystems Engineering
SN - 1615-7591
IS - 6
ER -