Optimization of enzymatic biodiesel synthesis using RSM in high pressure carbon dioxide and its scale up

Myunggu Lee; Dohoon Lee; Jaehoon Cho; Junhac Lee; Sangyong Kim; Seung Wook Kim; Chulhwan Park

doi:10.1007/s00449-013-0903-9

Optimization of enzymatic biodiesel synthesis using RSM in high pressure carbon dioxide and its scale up

Myunggu Lee, Dohoon Lee, Jaehoon Cho, Junhac Lee, Sangyong Kim, Seung Wook Kim, Chulhwan Park

Department of Chemical and Biological Engineering

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Enzymatic synthesis of biodiesel by the transesterification of canola oil and methanol in high pressure carbon dioxide [HPCO₂: near-critical and supercritical carbon dioxide (NcCO₂ and ScCO₂)] was optimized using response surface methodology (RSM). RSM based on 5-level-5-factor central composite rotatable design (CCRD) was used to evaluate the effects of temperature, pressure, enzyme loading, substrate molar ratio, and time on the conversion to biodiesel by transesterification. Finally, batch reactions for biodiesel synthesis were preformed in a 100 mL and 7 L high-pressure stirred batch reactors.

Original language	English
Pages (from-to)	775-780
Number of pages	6
Journal	Bioprocess and Biosystems Engineering
Volume	36
Issue number	6
DOIs	https://doi.org/10.1007/s00449-013-0903-9
Publication status	Published - 2013 Jun

Keywords

High pressure carbon dioxide
Lipase
Optimization
Response surface methodology
Transesterification

ASJC Scopus subject areas

Biotechnology
Bioengineering

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10.1007/s00449-013-0903-9

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title = "Optimization of enzymatic biodiesel synthesis using RSM in high pressure carbon dioxide and its scale up",

abstract = "Enzymatic synthesis of biodiesel by the transesterification of canola oil and methanol in high pressure carbon dioxide [HPCO2: near-critical and supercritical carbon dioxide (NcCO2 and ScCO2)] was optimized using response surface methodology (RSM). RSM based on 5-level-5-factor central composite rotatable design (CCRD) was used to evaluate the effects of temperature, pressure, enzyme loading, substrate molar ratio, and time on the conversion to biodiesel by transesterification. Finally, batch reactions for biodiesel synthesis were preformed in a 100 mL and 7 L high-pressure stirred batch reactors.",

keywords = "High pressure carbon dioxide, Lipase, Optimization, Response surface methodology, Transesterification",

author = "Myunggu Lee and Dohoon Lee and Jaehoon Cho and Junhac Lee and Sangyong Kim and Kim, {Seung Wook} and Chulhwan Park",

note = "Funding Information: Acknowledgments This work was funded by the Industrial Strategic Technology Development Program of the Ministry of Knowledge Funding Information: Economy (MKE), Korea and by the Basic Research Program of the Korea Institute of Industrial Technology (KITECH). This research was also supported by the Knowledge-based Environmental Service Human Resource Development Project of Korea Ministry of Environment (MOE) and the Research Grant from Kwangwoon University in 2013. The 7 L high-pressure stirred batch reactor was provided by Hanil Corporation, Korea.",

year = "2013",

month = jun,

doi = "10.1007/s00449-013-0903-9",

language = "English",

volume = "36",

pages = "775--780",

journal = "Bioprocess and Biosystems Engineering",

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T1 - Optimization of enzymatic biodiesel synthesis using RSM in high pressure carbon dioxide and its scale up

AU - Lee, Myunggu

AU - Lee, Dohoon

AU - Cho, Jaehoon

AU - Lee, Junhac

AU - Kim, Sangyong

AU - Kim, Seung Wook

AU - Park, Chulhwan

N1 - Funding Information: Acknowledgments This work was funded by the Industrial Strategic Technology Development Program of the Ministry of Knowledge Funding Information: Economy (MKE), Korea and by the Basic Research Program of the Korea Institute of Industrial Technology (KITECH). This research was also supported by the Knowledge-based Environmental Service Human Resource Development Project of Korea Ministry of Environment (MOE) and the Research Grant from Kwangwoon University in 2013. The 7 L high-pressure stirred batch reactor was provided by Hanil Corporation, Korea.

PY - 2013/6

Y1 - 2013/6

N2 - Enzymatic synthesis of biodiesel by the transesterification of canola oil and methanol in high pressure carbon dioxide [HPCO2: near-critical and supercritical carbon dioxide (NcCO2 and ScCO2)] was optimized using response surface methodology (RSM). RSM based on 5-level-5-factor central composite rotatable design (CCRD) was used to evaluate the effects of temperature, pressure, enzyme loading, substrate molar ratio, and time on the conversion to biodiesel by transesterification. Finally, batch reactions for biodiesel synthesis were preformed in a 100 mL and 7 L high-pressure stirred batch reactors.

AB - Enzymatic synthesis of biodiesel by the transesterification of canola oil and methanol in high pressure carbon dioxide [HPCO2: near-critical and supercritical carbon dioxide (NcCO2 and ScCO2)] was optimized using response surface methodology (RSM). RSM based on 5-level-5-factor central composite rotatable design (CCRD) was used to evaluate the effects of temperature, pressure, enzyme loading, substrate molar ratio, and time on the conversion to biodiesel by transesterification. Finally, batch reactions for biodiesel synthesis were preformed in a 100 mL and 7 L high-pressure stirred batch reactors.

KW - High pressure carbon dioxide

KW - Lipase

KW - Optimization

KW - Response surface methodology

KW - Transesterification

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JO - Bioprocess and Biosystems Engineering

JF - Bioprocess and Biosystems Engineering

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IS - 6

ER -

Optimization of enzymatic biodiesel synthesis using RSM in high pressure carbon dioxide and its scale up

Abstract

Keywords

ASJC Scopus subject areas

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