Optimization of Maillard reaction with ribose for enhancing anti-allergy effect of fish protein hydrolysates using response surface methodology

Sung Yong Yang, Se Wook Kim, Yoonsook Kim, Sang Hoon Lee, Hyeonjin Jeon, Kwang Won Lee

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Halibut is served on sushi and as sliced raw fish fillets. We investigated the optimal conditions of the Maillard reaction (MR) with ribose using response surface methodology to reduce the allergenicity of its protein. A 3-factored and 5-leveled central composite design was used, where the independent variables were substrate (ribose) concentration (X1, %), reaction time (X2, min), and pH (X3), while the dependent variables were browning index (Y1, absorbance at 420 nm), DPPH scavenging (Y2, EC50 mg/mL), FRAP (Y3, mM FeSO4/mg extract) and β-hexosaminidase release (Y4, %). The optimal conditions were obtained as follows: X1, 28.36%; X2, 38.09 min; X3, 8.26. Maillard reaction products of fish protein hydrolysate (MFPH) reduced the amount of nitric oxide synthesis compared to the untreated FPH, and had a significant anti-allergy effect on β-hexosaminidase and histamine release, compared with that of the FPH control. We concluded that MFPH, which had better antioxidant and anti-allergy activities than untreated FPH, can be used as an improved dietary source.

Original languageEnglish
Pages (from-to)420-425
Number of pages6
JournalFood Chemistry
Volume176
DOIs
Publication statusPublished - 2015 Jun 1

Fingerprint

fish protein hydrolysate
Fish Proteins
Allergies
Protein Hydrolysates
Maillard Reaction
beta-N-acetylhexosaminidase
Hexosaminidases
Maillard reaction products
Ribose
ribose
Maillard reaction
response surface methodology
Reaction products
hypersensitivity
Hypersensitivity
sushi
raw fish
fish fillets
halibut
allergenicity

Keywords

  • Anti-allergy effect
  • KFish protein hydrolysate
  • Maillard reaction
  • Response surface methodology
  • Ribose

ASJC Scopus subject areas

  • Food Science
  • Analytical Chemistry

Cite this

Optimization of Maillard reaction with ribose for enhancing anti-allergy effect of fish protein hydrolysates using response surface methodology. / Yang, Sung Yong; Kim, Se Wook; Kim, Yoonsook; Lee, Sang Hoon; Jeon, Hyeonjin; Lee, Kwang Won.

In: Food Chemistry, Vol. 176, 01.06.2015, p. 420-425.

Research output: Contribution to journalArticle

Yang, Sung Yong ; Kim, Se Wook ; Kim, Yoonsook ; Lee, Sang Hoon ; Jeon, Hyeonjin ; Lee, Kwang Won. / Optimization of Maillard reaction with ribose for enhancing anti-allergy effect of fish protein hydrolysates using response surface methodology. In: Food Chemistry. 2015 ; Vol. 176. pp. 420-425.
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