Outbreak of febrile respiratory illness caused by adenovirus at a south Korean military training facility

Clinical and radiological characteristics of adenovirus pneumonia

Se Min Hwang, Dong Ean Park, You In Yang, Sung Jin Park, Hee Kyeong Lee, Min Jeong Kim, Byung-Chul Chun

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Adenovirus often causes respiratory disease outbreaks in military training soldiers. Compared with adenovirus pneumonia in young military adults, symptoms arising from febrile respiratory illness (FRI) caused by adenovirus have not been previously evaluated in Korean soldiers.We conducted an event-based outbreak investigation involving 712 male soldiers aged 19 to 21 years from March 14 to 30, 2012 to evaluate the epidemiological and clinical characteristics of patients with pneumonia and FRI caused by adenovirus. We described the laboratory and radiological characteristics of patients with adenovirus pneumonia. Among these, 407 cases of FRI and 15 cases of pneumonia were identified through active surveillance (attack rate of FRI, 57.16z; attack rate of pneumonia, 2.11z). Fire training and march training may present environmental risk factors for adenovirus-associated outbreaks. Most symptoms were mild. The most frequent symptom in patients with pneumonia and FRI was cough. Patients with pneumonia were associated with an increased incidence of dizziness (crude odds ratio [cOR], 9.65; 95z confidence interval [CI], 2.38-37.15) and a decreased incidence of rhinorrhea (cOR, 0.15; 95z CI, 0.04-0.53) during adenovirus-associated outbreaks. Differential leukocyte count revealed high monocytes, low lymphocytes, and low eosinophils, and chest computed tomography revealed a consolidation pattern and right lobar pneumonia. These findings warrant a high level of suspicion for adenovirus pneumonia.

Original languageEnglish
Pages (from-to)359-365
Number of pages7
JournalJapanese Journal of Infectious Diseases
Volume66
Issue number5
DOIs
Publication statusPublished - 2013 Sep 25

Fingerprint

Military Facilities
Adenoviridae
Disease Outbreaks
Pneumonia
Fever
Military Personnel
Odds Ratio
Confidence Intervals
Incidence
Dizziness
Respiratory Rate
Leukocyte Count
Cough
Eosinophils
Monocytes
Young Adult
Thorax
Tomography
Lymphocytes

Keywords

  • Adenovirus
  • Febrile respiratory illness
  • Pneumonia
  • Risk factor

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Outbreak of febrile respiratory illness caused by adenovirus at a south Korean military training facility : Clinical and radiological characteristics of adenovirus pneumonia. / Hwang, Se Min; Park, Dong Ean; Yang, You In; Park, Sung Jin; Lee, Hee Kyeong; Kim, Min Jeong; Chun, Byung-Chul.

In: Japanese Journal of Infectious Diseases, Vol. 66, No. 5, 25.09.2013, p. 359-365.

Research output: Contribution to journalArticle

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