Outbreak of febrile respiratory illness caused by adenovirus at a south Korean military training facility: Clinical and radiological characteristics of adenovirus pneumonia

Se Min Hwang, Dong Ean Park, You In Yang, Sung Jin Park, Hee Kyeong Lee, Min Jeong Kim, Byung Chul Chun

    Research output: Contribution to journalArticlepeer-review

    20 Citations (Scopus)

    Abstract

    Adenovirus often causes respiratory disease outbreaks in military training soldiers. Compared with adenovirus pneumonia in young military adults, symptoms arising from febrile respiratory illness (FRI) caused by adenovirus have not been previously evaluated in Korean soldiers.We conducted an event-based outbreak investigation involving 712 male soldiers aged 19 to 21 years from March 14 to 30, 2012 to evaluate the epidemiological and clinical characteristics of patients with pneumonia and FRI caused by adenovirus. We described the laboratory and radiological characteristics of patients with adenovirus pneumonia. Among these, 407 cases of FRI and 15 cases of pneumonia were identified through active surveillance (attack rate of FRI, 57.16z; attack rate of pneumonia, 2.11z). Fire training and march training may present environmental risk factors for adenovirus-associated outbreaks. Most symptoms were mild. The most frequent symptom in patients with pneumonia and FRI was cough. Patients with pneumonia were associated with an increased incidence of dizziness (crude odds ratio [cOR], 9.65; 95z confidence interval [CI], 2.38-37.15) and a decreased incidence of rhinorrhea (cOR, 0.15; 95z CI, 0.04-0.53) during adenovirus-associated outbreaks. Differential leukocyte count revealed high monocytes, low lymphocytes, and low eosinophils, and chest computed tomography revealed a consolidation pattern and right lobar pneumonia. These findings warrant a high level of suspicion for adenovirus pneumonia.

    Original languageEnglish
    Pages (from-to)359-365
    Number of pages7
    JournalJapanese journal of infectious diseases
    Volume66
    Issue number5
    DOIs
    Publication statusPublished - 2013

    Keywords

    • Adenovirus
    • Febrile respiratory illness
    • Pneumonia
    • Risk factor

    ASJC Scopus subject areas

    • Microbiology (medical)
    • Infectious Diseases

    Fingerprint

    Dive into the research topics of 'Outbreak of febrile respiratory illness caused by adenovirus at a south Korean military training facility: Clinical and radiological characteristics of adenovirus pneumonia'. Together they form a unique fingerprint.

    Cite this