Outcome after one-stage repair of tetralogy of Fallot

C. Lee, C. H. Lee, S. C. Kim, C. Lim, Y. H. Chang, C. H. Kang, Won-Min Jo, Woong Han Kim

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Aim. The purpose of this study was to evaluate the outcome after one-stage repair of tetralogy of Fallot (TOF). Methods. Between May 1997 and December 2002, 240 patients with a median age of 9 months (1 month-48 years) underwent one-stage repair of TOF. Closure of ventricular septal defect (VSD) was accomplished through the right atrium in 171 (71.3%) patients and through the right ventricle in 69 (28.7%) patients. For the reconstruction of the right ventricular outflow tract (RVOT), transannular repair was performed in 151 (62.9%) patients, and non-transannular repair was performed in 89 (37.1%) patients. Follow-up was complete, averaging 40±17.6 months (3 months-5.8 years). Results. There were 2 (0.8%) operative deaths. Between early repair group (age under 6 months) and late repair group (age above 6 months), there were no differences in the method of RVOT reconstruction (transannular vs non-transannular) and the need for branch pulmonary artery angioplasty. Early repair group had more transventricular VSD closure than late repair group (46% vs 22%, P<0.05). Duration of inotropic support and intensive care unit (ICU) stay were longer in the early repair group (P<0.05). Five patients required reoperations due to RVOT obstruction (n=3), and residual VSD (n=2). Kaplan-Meier freedom from reoperation at 5 years was 98.3±1%. Nine patients underwent catheter intervention for branch pulmonary artery stenosis. Freedom from reintervention at 5 years was 95.4±1.5%. All survivors are currently asymptomatic. Conclusion. One-stage repair of TOF could be performed with low mortality and morbidity. Especially, early one-stage repair in symptomatic infant could be performed with low risk, eliminating the need for palliative procedures.

Original languageEnglish
Pages (from-to)65-70
Number of pages6
JournalJournal of Cardiovascular Surgery
Volume47
Issue number1
Publication statusPublished - 2006 Feb 1
Externally publishedYes

Fingerprint

Tetralogy of Fallot
Ventricular Heart Septal Defects
Reoperation
Age Groups
Ventricular Outflow Obstruction
Patient Rights
Heart Atria
Angioplasty
Pulmonary Artery
Heart Ventricles
Intensive Care Units
Survivors
Catheters
Morbidity
Mortality

Keywords

  • Cardiac surgical procedures
  • Surgery
  • Tetralogy of Fallot

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

Cite this

Lee, C., Lee, C. H., Kim, S. C., Lim, C., Chang, Y. H., Kang, C. H., ... Kim, W. H. (2006). Outcome after one-stage repair of tetralogy of Fallot. Journal of Cardiovascular Surgery, 47(1), 65-70.

Outcome after one-stage repair of tetralogy of Fallot. / Lee, C.; Lee, C. H.; Kim, S. C.; Lim, C.; Chang, Y. H.; Kang, C. H.; Jo, Won-Min; Kim, Woong Han.

In: Journal of Cardiovascular Surgery, Vol. 47, No. 1, 01.02.2006, p. 65-70.

Research output: Contribution to journalArticle

Lee, C, Lee, CH, Kim, SC, Lim, C, Chang, YH, Kang, CH, Jo, W-M & Kim, WH 2006, 'Outcome after one-stage repair of tetralogy of Fallot', Journal of Cardiovascular Surgery, vol. 47, no. 1, pp. 65-70.
Lee C, Lee CH, Kim SC, Lim C, Chang YH, Kang CH et al. Outcome after one-stage repair of tetralogy of Fallot. Journal of Cardiovascular Surgery. 2006 Feb 1;47(1):65-70.
Lee, C. ; Lee, C. H. ; Kim, S. C. ; Lim, C. ; Chang, Y. H. ; Kang, C. H. ; Jo, Won-Min ; Kim, Woong Han. / Outcome after one-stage repair of tetralogy of Fallot. In: Journal of Cardiovascular Surgery. 2006 ; Vol. 47, No. 1. pp. 65-70.
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abstract = "Aim. The purpose of this study was to evaluate the outcome after one-stage repair of tetralogy of Fallot (TOF). Methods. Between May 1997 and December 2002, 240 patients with a median age of 9 months (1 month-48 years) underwent one-stage repair of TOF. Closure of ventricular septal defect (VSD) was accomplished through the right atrium in 171 (71.3{\%}) patients and through the right ventricle in 69 (28.7{\%}) patients. For the reconstruction of the right ventricular outflow tract (RVOT), transannular repair was performed in 151 (62.9{\%}) patients, and non-transannular repair was performed in 89 (37.1{\%}) patients. Follow-up was complete, averaging 40±17.6 months (3 months-5.8 years). Results. There were 2 (0.8{\%}) operative deaths. Between early repair group (age under 6 months) and late repair group (age above 6 months), there were no differences in the method of RVOT reconstruction (transannular vs non-transannular) and the need for branch pulmonary artery angioplasty. Early repair group had more transventricular VSD closure than late repair group (46{\%} vs 22{\%}, P<0.05). Duration of inotropic support and intensive care unit (ICU) stay were longer in the early repair group (P<0.05). Five patients required reoperations due to RVOT obstruction (n=3), and residual VSD (n=2). Kaplan-Meier freedom from reoperation at 5 years was 98.3±1{\%}. Nine patients underwent catheter intervention for branch pulmonary artery stenosis. Freedom from reintervention at 5 years was 95.4±1.5{\%}. All survivors are currently asymptomatic. Conclusion. One-stage repair of TOF could be performed with low mortality and morbidity. Especially, early one-stage repair in symptomatic infant could be performed with low risk, eliminating the need for palliative procedures.",
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AU - Lee, C. H.

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AU - Lim, C.

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N2 - Aim. The purpose of this study was to evaluate the outcome after one-stage repair of tetralogy of Fallot (TOF). Methods. Between May 1997 and December 2002, 240 patients with a median age of 9 months (1 month-48 years) underwent one-stage repair of TOF. Closure of ventricular septal defect (VSD) was accomplished through the right atrium in 171 (71.3%) patients and through the right ventricle in 69 (28.7%) patients. For the reconstruction of the right ventricular outflow tract (RVOT), transannular repair was performed in 151 (62.9%) patients, and non-transannular repair was performed in 89 (37.1%) patients. Follow-up was complete, averaging 40±17.6 months (3 months-5.8 years). Results. There were 2 (0.8%) operative deaths. Between early repair group (age under 6 months) and late repair group (age above 6 months), there were no differences in the method of RVOT reconstruction (transannular vs non-transannular) and the need for branch pulmonary artery angioplasty. Early repair group had more transventricular VSD closure than late repair group (46% vs 22%, P<0.05). Duration of inotropic support and intensive care unit (ICU) stay were longer in the early repair group (P<0.05). Five patients required reoperations due to RVOT obstruction (n=3), and residual VSD (n=2). Kaplan-Meier freedom from reoperation at 5 years was 98.3±1%. Nine patients underwent catheter intervention for branch pulmonary artery stenosis. Freedom from reintervention at 5 years was 95.4±1.5%. All survivors are currently asymptomatic. Conclusion. One-stage repair of TOF could be performed with low mortality and morbidity. Especially, early one-stage repair in symptomatic infant could be performed with low risk, eliminating the need for palliative procedures.

AB - Aim. The purpose of this study was to evaluate the outcome after one-stage repair of tetralogy of Fallot (TOF). Methods. Between May 1997 and December 2002, 240 patients with a median age of 9 months (1 month-48 years) underwent one-stage repair of TOF. Closure of ventricular septal defect (VSD) was accomplished through the right atrium in 171 (71.3%) patients and through the right ventricle in 69 (28.7%) patients. For the reconstruction of the right ventricular outflow tract (RVOT), transannular repair was performed in 151 (62.9%) patients, and non-transannular repair was performed in 89 (37.1%) patients. Follow-up was complete, averaging 40±17.6 months (3 months-5.8 years). Results. There were 2 (0.8%) operative deaths. Between early repair group (age under 6 months) and late repair group (age above 6 months), there were no differences in the method of RVOT reconstruction (transannular vs non-transannular) and the need for branch pulmonary artery angioplasty. Early repair group had more transventricular VSD closure than late repair group (46% vs 22%, P<0.05). Duration of inotropic support and intensive care unit (ICU) stay were longer in the early repair group (P<0.05). Five patients required reoperations due to RVOT obstruction (n=3), and residual VSD (n=2). Kaplan-Meier freedom from reoperation at 5 years was 98.3±1%. Nine patients underwent catheter intervention for branch pulmonary artery stenosis. Freedom from reintervention at 5 years was 95.4±1.5%. All survivors are currently asymptomatic. Conclusion. One-stage repair of TOF could be performed with low mortality and morbidity. Especially, early one-stage repair in symptomatic infant could be performed with low risk, eliminating the need for palliative procedures.

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