Outcomes of management for potential deceased donors

J. C. Jeong, Myung-Gyu Kim, H. Ro, Y. J. Kim, H. C. Park, H. Y. Kwon, H. J. Jeon, J. Ha, C. Ahn, J. Yang

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Abstract

Backgrounds: Potential deceased donor management optimization is important for organ recovery maximization. Before optimization, the current state of donor management and predictors for organ recovery require analysis. Methods: We retrospectively analyzed organ procurement activity and medical management for 2005 to 2010 potential brain death donors at Seoul National University Hospital. Results: Of 316 contacts for potential brain-dead donors, 129 (39.7%) patients were transferred to the donor management team. Among the causes of transfer failure, issues related to proper donor management affected 33%. Expanded criteria donors were 17.9% of transferred donors. Organ recovery was successful in 111 (90.2%) donors. A total of 360 organs were recovered, corresponding to a mean of 2.92 ± 1.37 organs per donor. The absence of organ demand was an important cause of recovery failure among less transplanted organs. Brain death-related complications were identified as follows: acute kidney injury (AKI), defined by AKI network criteria, occurred in 19 (15.4%); cardiopulmonary resuscitation in 5 (3.1%); bacteremia in 12 (9.7%); thrombocytopenia in 24 (19.5%); and diabetes insipidus in 42 (34.1%). AKI was a significant independent risk factor for organ recovery failure in both the liver and kidney (odds ratio [OR] 0.147, 95% confidence interval [0.045, 0.473], P =.001; OR 0.096, 95% confidence interval [0.023, 0.392], P =.001, for kidney and liver, respectively). Conclusions: Both the transfer success rate and rate of organs transplanted per donor of potential deceased donors remained low in Korea. AKI during potential donor management was a risk factor for kidney and liver recovery failure.

Original languageEnglish
Pages (from-to)843-847
Number of pages5
JournalTransplantation Proceedings
Volume44
Issue number4
DOIs
Publication statusPublished - 2012 May 1
Externally publishedYes

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ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Jeong, J. C., Kim, M-G., Ro, H., Kim, Y. J., Park, H. C., Kwon, H. Y., Jeon, H. J., Ha, J., Ahn, C., & Yang, J. (2012). Outcomes of management for potential deceased donors. Transplantation Proceedings, 44(4), 843-847. https://doi.org/10.1016/j.transproceed.2012.01.102