Overview of the Korean longitudinal study on cognitive aging and dementia

Ji Won Han, Tae Hui Kim, Kyung Phil Kwak, Kayoung Kim, Bong Jo Kim, Shin Gyeom Kim, Jeong Lan Kim, Tae Hyun Kim, Seok Woo Moon, Jae Young Park, Joon Hyuk Park, Seonjeong Byun, Seung Wan Suh, Ji Young Seo, Yoonseop So, Seung Ho Ryu, Jong Chul Youn, Kyoung Hwan Lee, Dong Young Lee, Dong Woo Lee & 9 others Seok Bum Lee, Jung Jae Lee, Ju Ri Lee, Hyeon Jeong, Hyun-Ghang Jeong, Jin Hyeong Jhoo, Kyuhee Han, Jong Woo Hong, Ki Woong Kim

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective Due to an unprecedented rate of population aging, South Korea is facing a dementia epidemic. For this reason, the Korean Longitudinal Study on Cognitive Aging and Dementia (KLOSCAD) was launched in 2009 with support from the Korean Health Industry Development Institute to investigate the epidemiology, biopsychosocial risk factors, and outcomes of dementia and dementia-related conditions. Methods The KLOSCAD is the first nationwide multi-center population-based prospective cohort study. In October 2010, 12,694 individuals were randomly sampled from residents aged 60 years or older who lived in 13 districts across South Korea. In the baseline assessment, which was conducted from November 2010 through October 2012, 6,818 (53.7%) individuals participated. Follow-up assessments have been conducted every two years, with the first follow-up assessment conducted between November 2012 and October 2014, and the second between November 2014 and October 2016. The third is now in progress, and will span from November 2016 to October 2018. Diagnosis of cognitive disorders, neuropsychological battery, behavioral and psychological symptoms of dementia, activities of daily living, physical and neurologic examination and laboratory tests, life styles, quality of life, and identification of death were evaluated in each assessment. Results The cumulative drop-out rate at the second follow-up assessment was 38.7%. Dementia and mild cognitive impairment were 5.0% and 27.0%, respectively. Conclusion The KLOSCAD may provide strong scientific evidence for advancing the fight against dementia both in Korea and globally.

Original languageEnglish
Pages (from-to)767-774
Number of pages8
JournalPsychiatry Investigation
Volume15
Issue number8
DOIs
Publication statusPublished - 2018 Aug 1

Fingerprint

Longitudinal Studies
Dementia
Republic of Korea
Quality of Life
Cognitive Aging
Behavioral Symptoms
Neurologic Examination
Korea
Activities of Daily Living
Population
Physical Examination
Life Style
Industry
Epidemiology
Cohort Studies
Prospective Studies
Psychology
Health

Keywords

  • Cognitive ageing
  • Cohort study
  • Community
  • Dementia
  • Korea
  • Longitudinal
  • Mild cognitive impairment
  • Multicenter
  • Prospective

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

Han, J. W., Kim, T. H., Kwak, K. P., Kim, K., Kim, B. J., Kim, S. G., ... Kim, K. W. (2018). Overview of the Korean longitudinal study on cognitive aging and dementia. Psychiatry Investigation, 15(8), 767-774. https://doi.org/10.30773/pi.2018.06.02

Overview of the Korean longitudinal study on cognitive aging and dementia. / Han, Ji Won; Kim, Tae Hui; Kwak, Kyung Phil; Kim, Kayoung; Kim, Bong Jo; Kim, Shin Gyeom; Kim, Jeong Lan; Kim, Tae Hyun; Moon, Seok Woo; Park, Jae Young; Park, Joon Hyuk; Byun, Seonjeong; Suh, Seung Wan; Seo, Ji Young; So, Yoonseop; Ryu, Seung Ho; Youn, Jong Chul; Lee, Kyoung Hwan; Lee, Dong Young; Lee, Dong Woo; Lee, Seok Bum; Lee, Jung Jae; Lee, Ju Ri; Jeong, Hyeon; Jeong, Hyun-Ghang; Jhoo, Jin Hyeong; Han, Kyuhee; Hong, Jong Woo; Kim, Ki Woong.

In: Psychiatry Investigation, Vol. 15, No. 8, 01.08.2018, p. 767-774.

Research output: Contribution to journalArticle

Han, JW, Kim, TH, Kwak, KP, Kim, K, Kim, BJ, Kim, SG, Kim, JL, Kim, TH, Moon, SW, Park, JY, Park, JH, Byun, S, Suh, SW, Seo, JY, So, Y, Ryu, SH, Youn, JC, Lee, KH, Lee, DY, Lee, DW, Lee, SB, Lee, JJ, Lee, JR, Jeong, H, Jeong, H-G, Jhoo, JH, Han, K, Hong, JW & Kim, KW 2018, 'Overview of the Korean longitudinal study on cognitive aging and dementia', Psychiatry Investigation, vol. 15, no. 8, pp. 767-774. https://doi.org/10.30773/pi.2018.06.02
Han, Ji Won ; Kim, Tae Hui ; Kwak, Kyung Phil ; Kim, Kayoung ; Kim, Bong Jo ; Kim, Shin Gyeom ; Kim, Jeong Lan ; Kim, Tae Hyun ; Moon, Seok Woo ; Park, Jae Young ; Park, Joon Hyuk ; Byun, Seonjeong ; Suh, Seung Wan ; Seo, Ji Young ; So, Yoonseop ; Ryu, Seung Ho ; Youn, Jong Chul ; Lee, Kyoung Hwan ; Lee, Dong Young ; Lee, Dong Woo ; Lee, Seok Bum ; Lee, Jung Jae ; Lee, Ju Ri ; Jeong, Hyeon ; Jeong, Hyun-Ghang ; Jhoo, Jin Hyeong ; Han, Kyuhee ; Hong, Jong Woo ; Kim, Ki Woong. / Overview of the Korean longitudinal study on cognitive aging and dementia. In: Psychiatry Investigation. 2018 ; Vol. 15, No. 8. pp. 767-774.
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AU - Han, Ji Won

AU - Kim, Tae Hui

AU - Kwak, Kyung Phil

AU - Kim, Kayoung

AU - Kim, Bong Jo

AU - Kim, Shin Gyeom

AU - Kim, Jeong Lan

AU - Kim, Tae Hyun

AU - Moon, Seok Woo

AU - Park, Jae Young

AU - Park, Joon Hyuk

AU - Byun, Seonjeong

AU - Suh, Seung Wan

AU - Seo, Ji Young

AU - So, Yoonseop

AU - Ryu, Seung Ho

AU - Youn, Jong Chul

AU - Lee, Kyoung Hwan

AU - Lee, Dong Young

AU - Lee, Dong Woo

AU - Lee, Seok Bum

AU - Lee, Jung Jae

AU - Lee, Ju Ri

AU - Jeong, Hyeon

AU - Jeong, Hyun-Ghang

AU - Jhoo, Jin Hyeong

AU - Han, Kyuhee

AU - Hong, Jong Woo

AU - Kim, Ki Woong

PY - 2018/8/1

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N2 - Objective Due to an unprecedented rate of population aging, South Korea is facing a dementia epidemic. For this reason, the Korean Longitudinal Study on Cognitive Aging and Dementia (KLOSCAD) was launched in 2009 with support from the Korean Health Industry Development Institute to investigate the epidemiology, biopsychosocial risk factors, and outcomes of dementia and dementia-related conditions. Methods The KLOSCAD is the first nationwide multi-center population-based prospective cohort study. In October 2010, 12,694 individuals were randomly sampled from residents aged 60 years or older who lived in 13 districts across South Korea. In the baseline assessment, which was conducted from November 2010 through October 2012, 6,818 (53.7%) individuals participated. Follow-up assessments have been conducted every two years, with the first follow-up assessment conducted between November 2012 and October 2014, and the second between November 2014 and October 2016. The third is now in progress, and will span from November 2016 to October 2018. Diagnosis of cognitive disorders, neuropsychological battery, behavioral and psychological symptoms of dementia, activities of daily living, physical and neurologic examination and laboratory tests, life styles, quality of life, and identification of death were evaluated in each assessment. Results The cumulative drop-out rate at the second follow-up assessment was 38.7%. Dementia and mild cognitive impairment were 5.0% and 27.0%, respectively. Conclusion The KLOSCAD may provide strong scientific evidence for advancing the fight against dementia both in Korea and globally.

AB - Objective Due to an unprecedented rate of population aging, South Korea is facing a dementia epidemic. For this reason, the Korean Longitudinal Study on Cognitive Aging and Dementia (KLOSCAD) was launched in 2009 with support from the Korean Health Industry Development Institute to investigate the epidemiology, biopsychosocial risk factors, and outcomes of dementia and dementia-related conditions. Methods The KLOSCAD is the first nationwide multi-center population-based prospective cohort study. In October 2010, 12,694 individuals were randomly sampled from residents aged 60 years or older who lived in 13 districts across South Korea. In the baseline assessment, which was conducted from November 2010 through October 2012, 6,818 (53.7%) individuals participated. Follow-up assessments have been conducted every two years, with the first follow-up assessment conducted between November 2012 and October 2014, and the second between November 2014 and October 2016. The third is now in progress, and will span from November 2016 to October 2018. Diagnosis of cognitive disorders, neuropsychological battery, behavioral and psychological symptoms of dementia, activities of daily living, physical and neurologic examination and laboratory tests, life styles, quality of life, and identification of death were evaluated in each assessment. Results The cumulative drop-out rate at the second follow-up assessment was 38.7%. Dementia and mild cognitive impairment were 5.0% and 27.0%, respectively. Conclusion The KLOSCAD may provide strong scientific evidence for advancing the fight against dementia both in Korea and globally.

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KW - Cohort study

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KW - Korea

KW - Longitudinal

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KW - Prospective

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