Abstract
Chitosan was modified by coupling with linoleic acid through the 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide-mediated reaction to increase its amphipathicity for improved emulsification. The micelle formation of linoleic acid-modified chitosan in the 0.1 M acetic acid solution was enhanced by O/W emulsification with methylene chloride, an oil phase. The fluorescence spectra indicate that without emulsification the self-aggregation of LA-chitosan occurred at the concentration of 1.0 g/L or above, and with emulsification, selfaggregation was greatly enhanced followed by a stable micelle formation at 2.0 g/L. The addition of 1 M sodium chloride promoted the self-aggregation of LA-chitosan molecules both with and without emulsification. The micelles of LA-chitosan formed nanosize particles ranging from 200 to 600 nm. The LA-chitosan nanoparticles encapsulated the lipid soluble model compound, retinal acetate, with 50% efficiency.
| Original language | English |
|---|---|
| Pages (from-to) | 3135-3139 |
| Number of pages | 5 |
| Journal | Journal of Agricultural and Food Chemistry |
| Volume | 51 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2003 May 7 |
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Keywords
- Chemical modification
- Chitosan
- Emulsification
- Encapsulation
- Linoleic acid
- Micelles
- Nanoparticle
ASJC Scopus subject areas
- Agricultural and Biological Sciences (miscellaneous)
- Food Science
- Chemistry (miscellaneous)
Cite this
O/W emulsification for the self-aggregation and nanoparticle formation of linoleic acid-modified chitosan in the aqueous system. / Chen, Xi Guang; Lee, Chong M.; Park, Hyun Jin.
In: Journal of Agricultural and Food Chemistry, Vol. 51, No. 10, 07.05.2003, p. 3135-3139.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - O/W emulsification for the self-aggregation and nanoparticle formation of linoleic acid-modified chitosan in the aqueous system
AU - Chen, Xi Guang
AU - Lee, Chong M.
AU - Park, Hyun Jin
PY - 2003/5/7
Y1 - 2003/5/7
N2 - Chitosan was modified by coupling with linoleic acid through the 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide-mediated reaction to increase its amphipathicity for improved emulsification. The micelle formation of linoleic acid-modified chitosan in the 0.1 M acetic acid solution was enhanced by O/W emulsification with methylene chloride, an oil phase. The fluorescence spectra indicate that without emulsification the self-aggregation of LA-chitosan occurred at the concentration of 1.0 g/L or above, and with emulsification, selfaggregation was greatly enhanced followed by a stable micelle formation at 2.0 g/L. The addition of 1 M sodium chloride promoted the self-aggregation of LA-chitosan molecules both with and without emulsification. The micelles of LA-chitosan formed nanosize particles ranging from 200 to 600 nm. The LA-chitosan nanoparticles encapsulated the lipid soluble model compound, retinal acetate, with 50% efficiency.
AB - Chitosan was modified by coupling with linoleic acid through the 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide-mediated reaction to increase its amphipathicity for improved emulsification. The micelle formation of linoleic acid-modified chitosan in the 0.1 M acetic acid solution was enhanced by O/W emulsification with methylene chloride, an oil phase. The fluorescence spectra indicate that without emulsification the self-aggregation of LA-chitosan occurred at the concentration of 1.0 g/L or above, and with emulsification, selfaggregation was greatly enhanced followed by a stable micelle formation at 2.0 g/L. The addition of 1 M sodium chloride promoted the self-aggregation of LA-chitosan molecules both with and without emulsification. The micelles of LA-chitosan formed nanosize particles ranging from 200 to 600 nm. The LA-chitosan nanoparticles encapsulated the lipid soluble model compound, retinal acetate, with 50% efficiency.
KW - Chemical modification
KW - Chitosan
KW - Emulsification
KW - Encapsulation
KW - Linoleic acid
KW - Micelles
KW - Nanoparticle
UR - http://www.scopus.com/inward/record.url?scp=0038746780&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0038746780&partnerID=8YFLogxK
U2 - 10.1021/jf0208482
DO - 10.1021/jf0208482
M3 - Article
C2 - 12720404
AN - SCOPUS:0038746780
VL - 51
SP - 3135
EP - 3139
JO - Journal of Agricultural and Food Chemistry
JF - Journal of Agricultural and Food Chemistry
SN - 0021-8561
IS - 10
ER -