Pain-relieving effects of acupuncture and electroacupuncture in an animal model of arthritic pain

Jin Hwan Oh; Sun Joon Bai; Zang Hee Cho; Hee Chul Han; Sun Seek Min; Insop Shim; Hye Jung Lee; Hyangsook Lee; Bae Hwan Lee

doi:10.1080/00207450500513948

Pain-relieving effects of acupuncture and electroacupuncture in an animal model of arthritic pain

Jin Hwan Oh, Sun Joon Bai, Zang Hee Cho, Hee Chul Han, Sun Seek Min, Insop Shim, Hye Jung Lee, Hyangsook Lee, Bae Hwan Lee

Department of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

The effects of acupuncture and electroacupuncture on an animal model of arthritic pain were examined. Under halothane anesthesia, arthritic pain was induced by the injection of carrageenan into the knee joint cavity of male Sprague-Dawley rats. Behavioral performance was tested before and after the termination of acupuncture or electroacupuncture. Electrophysiologically, the responses of afferents to a movement cycle were recorded before and after acupuncture or electroacupuncture. After the acupuncture procedure, the weight-bearing force of the rats was significantly improved and the neural responses to noxious movement stimulation were reduced. Electroacupuncture significantly improved weight-bearing behavior and inhibited neural responses of articular afferents to noxious stimulation. These results indicate that acupuncture and electroacupuncture may provide a potent strategy in relieving arthritic pain.

Original language	English
Pages (from-to)	1139-1156
Number of pages	18
Journal	International Journal of Neuroscience
Volume	116
Issue number	10
DOIs	https://doi.org/10.1080/00207450500513948
Publication status	Published - 2006 Oct 1

Keywords

Acupuncture
Arthritis
Articular afferent
Electroacupuncture
Pain
Weight bearing

ASJC Scopus subject areas

Neuroscience(all)

Access to Document

10.1080/00207450500513948

Cite this

@article{bd5efdd4bb2046e4b6c102eb326690f6,

title = "Pain-relieving effects of acupuncture and electroacupuncture in an animal model of arthritic pain",

abstract = "The effects of acupuncture and electroacupuncture on an animal model of arthritic pain were examined. Under halothane anesthesia, arthritic pain was induced by the injection of carrageenan into the knee joint cavity of male Sprague-Dawley rats. Behavioral performance was tested before and after the termination of acupuncture or electroacupuncture. Electrophysiologically, the responses of afferents to a movement cycle were recorded before and after acupuncture or electroacupuncture. After the acupuncture procedure, the weight-bearing force of the rats was significantly improved and the neural responses to noxious movement stimulation were reduced. Electroacupuncture significantly improved weight-bearing behavior and inhibited neural responses of articular afferents to noxious stimulation. These results indicate that acupuncture and electroacupuncture may provide a potent strategy in relieving arthritic pain.",

keywords = "Acupuncture, Arthritis, Articular afferent, Electroacupuncture, Pain, Weight bearing",

author = "Oh, {Jin Hwan} and Bai, {Sun Joon} and Cho, {Zang Hee} and Han, {Hee Chul} and Min, {Sun Seek} and Insop Shim and Lee, {Hye Jung} and Hyangsook Lee and Lee, {Bae Hwan}",

note = "Funding Information: Received 13 June 2005. This study was supported by a grant from the Korea Health 21 R&D Project (01-PJ9-PG1-01CO01-0003) by the SRC/ERC program of MOST/KOSEF and in part by Korea Institute of Oriental Medicine. The first two authors contributed equally to this work. Address correspondence to Bae Hwan Lee, Ph.D., Department of Physiology, Yonsei University College of Medicine, C.P.O. Box 8044, Seoul 120-752, Republic of Korea. E-mail: bhlee@yumc.yonsei.ac.kr",

year = "2006",

month = oct,

day = "1",

doi = "10.1080/00207450500513948",

language = "English",

volume = "116",

pages = "1139--1156",

journal = "International Journal of Neuroscience",

issn = "0020-7454",

publisher = "Informa Healthcare",

number = "10",

}

TY - JOUR

T1 - Pain-relieving effects of acupuncture and electroacupuncture in an animal model of arthritic pain

AU - Oh, Jin Hwan

AU - Bai, Sun Joon

AU - Cho, Zang Hee

AU - Han, Hee Chul

AU - Min, Sun Seek

AU - Shim, Insop

AU - Lee, Hye Jung

AU - Lee, Hyangsook

AU - Lee, Bae Hwan

N1 - Funding Information: Received 13 June 2005. This study was supported by a grant from the Korea Health 21 R&D Project (01-PJ9-PG1-01CO01-0003) by the SRC/ERC program of MOST/KOSEF and in part by Korea Institute of Oriental Medicine. The first two authors contributed equally to this work. Address correspondence to Bae Hwan Lee, Ph.D., Department of Physiology, Yonsei University College of Medicine, C.P.O. Box 8044, Seoul 120-752, Republic of Korea. E-mail: bhlee@yumc.yonsei.ac.kr

PY - 2006/10/1

Y1 - 2006/10/1

N2 - The effects of acupuncture and electroacupuncture on an animal model of arthritic pain were examined. Under halothane anesthesia, arthritic pain was induced by the injection of carrageenan into the knee joint cavity of male Sprague-Dawley rats. Behavioral performance was tested before and after the termination of acupuncture or electroacupuncture. Electrophysiologically, the responses of afferents to a movement cycle were recorded before and after acupuncture or electroacupuncture. After the acupuncture procedure, the weight-bearing force of the rats was significantly improved and the neural responses to noxious movement stimulation were reduced. Electroacupuncture significantly improved weight-bearing behavior and inhibited neural responses of articular afferents to noxious stimulation. These results indicate that acupuncture and electroacupuncture may provide a potent strategy in relieving arthritic pain.

AB - The effects of acupuncture and electroacupuncture on an animal model of arthritic pain were examined. Under halothane anesthesia, arthritic pain was induced by the injection of carrageenan into the knee joint cavity of male Sprague-Dawley rats. Behavioral performance was tested before and after the termination of acupuncture or electroacupuncture. Electrophysiologically, the responses of afferents to a movement cycle were recorded before and after acupuncture or electroacupuncture. After the acupuncture procedure, the weight-bearing force of the rats was significantly improved and the neural responses to noxious movement stimulation were reduced. Electroacupuncture significantly improved weight-bearing behavior and inhibited neural responses of articular afferents to noxious stimulation. These results indicate that acupuncture and electroacupuncture may provide a potent strategy in relieving arthritic pain.

KW - Acupuncture

KW - Arthritis

KW - Articular afferent

KW - Electroacupuncture

KW - Pain

KW - Weight bearing

UR - http://www.scopus.com/inward/record.url?scp=33745598358&partnerID=8YFLogxK

U2 - 10.1080/00207450500513948

DO - 10.1080/00207450500513948

M3 - Article

C2 - 16923683

AN - SCOPUS:33745598358

SN - 0020-7454

VL - 116

SP - 1139

EP - 1156

JO - International Journal of Neuroscience

JF - International Journal of Neuroscience

IS - 10

ER -

Pain-relieving effects of acupuncture and electroacupuncture in an animal model of arthritic pain

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this