Pain-relieving effects of acupuncture and electroacupuncture in an animal model of arthritic pain

Jin Hwan Oh, Sun Joon Bai, Zang Hee Cho, Hee Chul Han, Sun Seek Min, Insop Shim, Hye Jung Lee, Hyangsook Lee, Bae Hwan Lee

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


The effects of acupuncture and electroacupuncture on an animal model of arthritic pain were examined. Under halothane anesthesia, arthritic pain was induced by the injection of carrageenan into the knee joint cavity of male Sprague-Dawley rats. Behavioral performance was tested before and after the termination of acupuncture or electroacupuncture. Electrophysiologically, the responses of afferents to a movement cycle were recorded before and after acupuncture or electroacupuncture. After the acupuncture procedure, the weight-bearing force of the rats was significantly improved and the neural responses to noxious movement stimulation were reduced. Electroacupuncture significantly improved weight-bearing behavior and inhibited neural responses of articular afferents to noxious stimulation. These results indicate that acupuncture and electroacupuncture may provide a potent strategy in relieving arthritic pain.

Original languageEnglish
Pages (from-to)1139-1156
Number of pages18
JournalInternational Journal of Neuroscience
Issue number10
Publication statusPublished - 2006 Oct 1


  • Acupuncture
  • Arthritis
  • Articular afferent
  • Electroacupuncture
  • Pain
  • Weight bearing

ASJC Scopus subject areas

  • Neuroscience(all)


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