Palladium-catalyzed tandem Heck and aldol reactions between 2-bromobenzaldehydes and functionalized alkenes leading to naphthalenes

Chan Sik Cho, Dong Kwon Lim, Jiao Qiang Zhang, Tae Jeong Kim, Sang Chul Shim

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

2-Bromobenzaldehydes react with an array of suitably functionalized alkenes in the presence of a catalytic amount of a palladium catalyst together with a base to afford the corresponding naphthalenes in moderate to good yields.

Original languageEnglish
Pages (from-to)5653-5656
Number of pages4
JournalTetrahedron Letters
Volume45
Issue number29
DOIs
Publication statusPublished - 2004 Jul 12
Externally publishedYes

Fingerprint

Naphthalenes
Palladium
Alkenes
Catalysts
2-bromobenzaldehyde
3-hydroxybutanal

Keywords

  • 2-Bromobenzaldehydes
  • Functionalized alkenes
  • Heck-aldol reaction
  • Naphthalenes
  • Palladium catalyst

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Palladium-catalyzed tandem Heck and aldol reactions between 2-bromobenzaldehydes and functionalized alkenes leading to naphthalenes. / Cho, Chan Sik; Lim, Dong Kwon; Zhang, Jiao Qiang; Kim, Tae Jeong; Shim, Sang Chul.

In: Tetrahedron Letters, Vol. 45, No. 29, 12.07.2004, p. 5653-5656.

Research output: Contribution to journalArticle

Cho, Chan Sik ; Lim, Dong Kwon ; Zhang, Jiao Qiang ; Kim, Tae Jeong ; Shim, Sang Chul. / Palladium-catalyzed tandem Heck and aldol reactions between 2-bromobenzaldehydes and functionalized alkenes leading to naphthalenes. In: Tetrahedron Letters. 2004 ; Vol. 45, No. 29. pp. 5653-5656.
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