Panenteritis as an Initial Presentation of Systemic Lupus Erythematosus

Han Ah Lee, Hye Gi Shim, Young Ho Seo, Sungjae Choi, Beomjae Lee, Young Ho Lee, Jong Dae Ji, Jae Hoon Kim, Gwan Gyu Song

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Lupus enteritis is a rare, severe complication of systemic lupus erythematosus (SLE), needing prompt diagnosis and proper management. However, SLE rarely presents as lupus enteritis at the time of initial diagnosis. Thus, delayed diagnosis and misdiagnosis are common. We report a case of a 25-year-old woman with lupus panenteritis. The patient had multiple hospitalizations for abdominal pain, nausea, and diarrhea, initially without any other symptoms suggestive of SLE, but was later observed to have malar rash and oral ulcers. Laboratory investigations were compatible with SLE, including positive antinuclear antibody (1:320) with speckled pattern. CT revealed diffuse hypodense submucosal thickening of the stomach, the entire small bowel, colon, appendix, and rectum. Treatment with high-dose corticosteroids followed by maintenance therapy with mycophenolate mofetil, hydroxychloroquine, and azathioprine resulted in clinical improvement. Diagnosis of lupus enteritis requires a high index of suspicion given the low incidence and nonspecific clinical findings.

Original languageEnglish
Pages (from-to)107-111
Number of pages5
JournalThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Volume67
Issue number2
DOIs
Publication statusPublished - 2016 Feb 1

Fingerprint

Systemic Lupus Erythematosus
Enteritis
Oral Ulcer
Mycophenolic Acid
Hydroxychloroquine
Delayed Diagnosis
Antinuclear Antibodies
Azathioprine
Appendix
Exanthema
Diagnostic Errors
Rectum
Nausea
Abdominal Pain
Diarrhea
Stomach
Adrenal Cortex Hormones
Colon
Hospitalization
Incidence

Keywords

  • Enteritis
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Panenteritis as an Initial Presentation of Systemic Lupus Erythematosus. / Lee, Han Ah; Shim, Hye Gi; Seo, Young Ho; Choi, Sungjae; Lee, Beomjae; Lee, Young Ho; Ji, Jong Dae; Kim, Jae Hoon; Song, Gwan Gyu.

In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, Vol. 67, No. 2, 01.02.2016, p. 107-111.

Research output: Contribution to journalArticle

@article{6c3eb889cac84618a5be2280df677acd,
title = "Panenteritis as an Initial Presentation of Systemic Lupus Erythematosus",
abstract = "Lupus enteritis is a rare, severe complication of systemic lupus erythematosus (SLE), needing prompt diagnosis and proper management. However, SLE rarely presents as lupus enteritis at the time of initial diagnosis. Thus, delayed diagnosis and misdiagnosis are common. We report a case of a 25-year-old woman with lupus panenteritis. The patient had multiple hospitalizations for abdominal pain, nausea, and diarrhea, initially without any other symptoms suggestive of SLE, but was later observed to have malar rash and oral ulcers. Laboratory investigations were compatible with SLE, including positive antinuclear antibody (1:320) with speckled pattern. CT revealed diffuse hypodense submucosal thickening of the stomach, the entire small bowel, colon, appendix, and rectum. Treatment with high-dose corticosteroids followed by maintenance therapy with mycophenolate mofetil, hydroxychloroquine, and azathioprine resulted in clinical improvement. Diagnosis of lupus enteritis requires a high index of suspicion given the low incidence and nonspecific clinical findings.",
keywords = "Enteritis, Systemic lupus erythematosus",
author = "Lee, {Han Ah} and Shim, {Hye Gi} and Seo, {Young Ho} and Sungjae Choi and Beomjae Lee and Lee, {Young Ho} and Ji, {Jong Dae} and Kim, {Jae Hoon} and Song, {Gwan Gyu}",
year = "2016",
month = "2",
day = "1",
doi = "10.4166/kjg.2016.67.2.107",
language = "English",
volume = "67",
pages = "107--111",
journal = "The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi",
issn = "1598-9992",
publisher = "Korean Society of Gastroenterology",
number = "2",

}

TY - JOUR

T1 - Panenteritis as an Initial Presentation of Systemic Lupus Erythematosus

AU - Lee, Han Ah

AU - Shim, Hye Gi

AU - Seo, Young Ho

AU - Choi, Sungjae

AU - Lee, Beomjae

AU - Lee, Young Ho

AU - Ji, Jong Dae

AU - Kim, Jae Hoon

AU - Song, Gwan Gyu

PY - 2016/2/1

Y1 - 2016/2/1

N2 - Lupus enteritis is a rare, severe complication of systemic lupus erythematosus (SLE), needing prompt diagnosis and proper management. However, SLE rarely presents as lupus enteritis at the time of initial diagnosis. Thus, delayed diagnosis and misdiagnosis are common. We report a case of a 25-year-old woman with lupus panenteritis. The patient had multiple hospitalizations for abdominal pain, nausea, and diarrhea, initially without any other symptoms suggestive of SLE, but was later observed to have malar rash and oral ulcers. Laboratory investigations were compatible with SLE, including positive antinuclear antibody (1:320) with speckled pattern. CT revealed diffuse hypodense submucosal thickening of the stomach, the entire small bowel, colon, appendix, and rectum. Treatment with high-dose corticosteroids followed by maintenance therapy with mycophenolate mofetil, hydroxychloroquine, and azathioprine resulted in clinical improvement. Diagnosis of lupus enteritis requires a high index of suspicion given the low incidence and nonspecific clinical findings.

AB - Lupus enteritis is a rare, severe complication of systemic lupus erythematosus (SLE), needing prompt diagnosis and proper management. However, SLE rarely presents as lupus enteritis at the time of initial diagnosis. Thus, delayed diagnosis and misdiagnosis are common. We report a case of a 25-year-old woman with lupus panenteritis. The patient had multiple hospitalizations for abdominal pain, nausea, and diarrhea, initially without any other symptoms suggestive of SLE, but was later observed to have malar rash and oral ulcers. Laboratory investigations were compatible with SLE, including positive antinuclear antibody (1:320) with speckled pattern. CT revealed diffuse hypodense submucosal thickening of the stomach, the entire small bowel, colon, appendix, and rectum. Treatment with high-dose corticosteroids followed by maintenance therapy with mycophenolate mofetil, hydroxychloroquine, and azathioprine resulted in clinical improvement. Diagnosis of lupus enteritis requires a high index of suspicion given the low incidence and nonspecific clinical findings.

KW - Enteritis

KW - Systemic lupus erythematosus

UR - http://www.scopus.com/inward/record.url?scp=85015350585&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85015350585&partnerID=8YFLogxK

U2 - 10.4166/kjg.2016.67.2.107

DO - 10.4166/kjg.2016.67.2.107

M3 - Article

C2 - 26907488

AN - SCOPUS:85015350585

VL - 67

SP - 107

EP - 111

JO - The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi

JF - The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi

SN - 1598-9992

IS - 2

ER -