Pauson-Khand-type reaction mediated by RH(I) catalysts

Nakcheol Jeong, Byung Ki Sung, Jin Sung Kim, Soon Bong Park, Sung Deok Seo, Jin Young Shin, Kyu Yeol In, Yoon Kyung Choi

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43 Citations (Scopus)

Abstract

Cocyclization of alkynes, alkenes, and carbon monoxide by transition metals (known as Pauson-Khand reaction when dicobalt octacarbonyl complexes are used) has been accepted as one of the most powerful tools in the synthesis of cyclopentenones. Despite significant progress in the various aspects of the reaction, we still needed new catalysts to expand the scope of the reaction further. We found rhodium (I) catalysts, e.g., RhCl(PPh 3) 3, trans-RhCl(CO)(PPh 3) 2, RhCl-(CO)(dppe), and trans-[RhCl(CO)(dppp)] 2, were also effective for this transformation. The scope and the efficiencies of the reaction could be tuned and expanded by the choice of catalysts. For example, we were able to devise an enantioselective PK-type reaction and a tandem strategy employing two catalysts in one pot. These results will be presented.

Original languageEnglish
Pages (from-to)85-91
Number of pages7
JournalPure and Applied Chemistry
Volume74
Issue number1
Publication statusPublished - 2002 Jul 14

ASJC Scopus subject areas

  • Chemistry(all)

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    Jeong, N., Sung, B. K., Kim, J. S., Park, S. B., Seo, S. D., Shin, J. Y., In, K. Y., & Choi, Y. K. (2002). Pauson-Khand-type reaction mediated by RH(I) catalysts. Pure and Applied Chemistry, 74(1), 85-91.