PE3-040 Recurrence Pattern of Atrial Tachyarrhythmia after Radiofrequency Catheter Ablation of Atrial Fibrillation and Its Responsiveness to Anti-Arrhythmic Drugs

Hoyoun Won, Junbeom Park, Jaemin Shim, Jong Youn Kim, Boyoung Joung, Moon Hyung Lee, Sung Soon Kim, Hui Nam Pak

Research output: Contribution to journalArticle

Abstract

Background: Whether anti-arrhythmic drug(AAD) responsiveness is improved after radiofrequency catheter ablation (RFCA) of AF is not clear. Methods: We reviewed the recurrence pattern and responsiveness to AAD of atrial tachycardia (AT)/fibrillation (AF) in 398 patients (307 men, mean age 56.0±10.9, 122 Persistent (Pe) AF who underwent radiofrequency catheter ablation (RFCA) of AF. Results: During 11.2±4.5 months follow-up, 130 (32.7%) patients recurred within 3month (ER) and 84 (21.1%) patients recurred after 3month (LR) of RFCA. 74.5% of ER remained in sinus rhythm (SR) with AAD, and slower heart rate at ER (Exp(B) 0.977; CI 0.961~0.992, p=0.004) and later timing of ER (Exp(B) 1.017; CI 1.002~1.031, p=0.021) after RFCA were independent predictors for LR. We used IC AAD (36.7%) or amiodarone (AMD;46.9%). SR restoration rate were 70.1% in class IC and 64.5% in AMD (p=0.664) within 15.2±34.3 days. PeAF (Exp(B) 5.924, CI 1.292~27.153, p=0.022) and LR (Exp(B) 9.042, CI 2.017~40.527, p=0.004) were independent predictor of failed SR conversion with AMD. The proportions of AT in recurred ECG were 31.5% in ER and 37.3% in LR, and AAD responsiveness of AT (65.0%) was not different to AF (69.0%, p=0.612). Conclusion: Slower heart rate at ER and later ER were predictors for LR. Overall AAD responsiveness was 67.6% after RFCA of AF, but the patients with LR and PeAF were predictors for poor responsiveness to AMD.

Original languageEnglish
Number of pages1
JournalJournal of Arrhythmia
Volume27
DOIs
Publication statusPublished - 2011 Jan 1
Externally publishedYes

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Catheter Ablation
Anti-Arrhythmia Agents
Tachycardia
Atrial Fibrillation
Recurrence
Pharmaceutical Preparations
Heart Rate
Amiodarone
Electrocardiography

Keywords

  • anti-arrhythmic drug
  • atrial fibrillation
  • radiofrequency catheter ablation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

PE3-040 Recurrence Pattern of Atrial Tachyarrhythmia after Radiofrequency Catheter Ablation of Atrial Fibrillation and Its Responsiveness to Anti-Arrhythmic Drugs. / Won, Hoyoun; Park, Junbeom; Shim, Jaemin; Youn Kim, Jong; Joung, Boyoung; Lee, Moon Hyung; Kim, Sung Soon; Pak, Hui Nam.

In: Journal of Arrhythmia, Vol. 27, 01.01.2011.

Research output: Contribution to journalArticle

Won, Hoyoun ; Park, Junbeom ; Shim, Jaemin ; Youn Kim, Jong ; Joung, Boyoung ; Lee, Moon Hyung ; Kim, Sung Soon ; Pak, Hui Nam. / PE3-040 Recurrence Pattern of Atrial Tachyarrhythmia after Radiofrequency Catheter Ablation of Atrial Fibrillation and Its Responsiveness to Anti-Arrhythmic Drugs. In: Journal of Arrhythmia. 2011 ; Vol. 27.
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abstract = "Background: Whether anti-arrhythmic drug(AAD) responsiveness is improved after radiofrequency catheter ablation (RFCA) of AF is not clear. Methods: We reviewed the recurrence pattern and responsiveness to AAD of atrial tachycardia (AT)/fibrillation (AF) in 398 patients (307 men, mean age 56.0±10.9, 122 Persistent (Pe) AF who underwent radiofrequency catheter ablation (RFCA) of AF. Results: During 11.2±4.5 months follow-up, 130 (32.7{\%}) patients recurred within 3month (ER) and 84 (21.1{\%}) patients recurred after 3month (LR) of RFCA. 74.5{\%} of ER remained in sinus rhythm (SR) with AAD, and slower heart rate at ER (Exp(B) 0.977; CI 0.961~0.992, p=0.004) and later timing of ER (Exp(B) 1.017; CI 1.002~1.031, p=0.021) after RFCA were independent predictors for LR. We used IC AAD (36.7{\%}) or amiodarone (AMD;46.9{\%}). SR restoration rate were 70.1{\%} in class IC and 64.5{\%} in AMD (p=0.664) within 15.2±34.3 days. PeAF (Exp(B) 5.924, CI 1.292~27.153, p=0.022) and LR (Exp(B) 9.042, CI 2.017~40.527, p=0.004) were independent predictor of failed SR conversion with AMD. The proportions of AT in recurred ECG were 31.5{\%} in ER and 37.3{\%} in LR, and AAD responsiveness of AT (65.0{\%}) was not different to AF (69.0{\%}, p=0.612). Conclusion: Slower heart rate at ER and later ER were predictors for LR. Overall AAD responsiveness was 67.6{\%} after RFCA of AF, but the patients with LR and PeAF were predictors for poor responsiveness to AMD.",
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T1 - PE3-040 Recurrence Pattern of Atrial Tachyarrhythmia after Radiofrequency Catheter Ablation of Atrial Fibrillation and Its Responsiveness to Anti-Arrhythmic Drugs

AU - Won, Hoyoun

AU - Park, Junbeom

AU - Shim, Jaemin

AU - Youn Kim, Jong

AU - Joung, Boyoung

AU - Lee, Moon Hyung

AU - Kim, Sung Soon

AU - Pak, Hui Nam

PY - 2011/1/1

Y1 - 2011/1/1

N2 - Background: Whether anti-arrhythmic drug(AAD) responsiveness is improved after radiofrequency catheter ablation (RFCA) of AF is not clear. Methods: We reviewed the recurrence pattern and responsiveness to AAD of atrial tachycardia (AT)/fibrillation (AF) in 398 patients (307 men, mean age 56.0±10.9, 122 Persistent (Pe) AF who underwent radiofrequency catheter ablation (RFCA) of AF. Results: During 11.2±4.5 months follow-up, 130 (32.7%) patients recurred within 3month (ER) and 84 (21.1%) patients recurred after 3month (LR) of RFCA. 74.5% of ER remained in sinus rhythm (SR) with AAD, and slower heart rate at ER (Exp(B) 0.977; CI 0.961~0.992, p=0.004) and later timing of ER (Exp(B) 1.017; CI 1.002~1.031, p=0.021) after RFCA were independent predictors for LR. We used IC AAD (36.7%) or amiodarone (AMD;46.9%). SR restoration rate were 70.1% in class IC and 64.5% in AMD (p=0.664) within 15.2±34.3 days. PeAF (Exp(B) 5.924, CI 1.292~27.153, p=0.022) and LR (Exp(B) 9.042, CI 2.017~40.527, p=0.004) were independent predictor of failed SR conversion with AMD. The proportions of AT in recurred ECG were 31.5% in ER and 37.3% in LR, and AAD responsiveness of AT (65.0%) was not different to AF (69.0%, p=0.612). Conclusion: Slower heart rate at ER and later ER were predictors for LR. Overall AAD responsiveness was 67.6% after RFCA of AF, but the patients with LR and PeAF were predictors for poor responsiveness to AMD.

AB - Background: Whether anti-arrhythmic drug(AAD) responsiveness is improved after radiofrequency catheter ablation (RFCA) of AF is not clear. Methods: We reviewed the recurrence pattern and responsiveness to AAD of atrial tachycardia (AT)/fibrillation (AF) in 398 patients (307 men, mean age 56.0±10.9, 122 Persistent (Pe) AF who underwent radiofrequency catheter ablation (RFCA) of AF. Results: During 11.2±4.5 months follow-up, 130 (32.7%) patients recurred within 3month (ER) and 84 (21.1%) patients recurred after 3month (LR) of RFCA. 74.5% of ER remained in sinus rhythm (SR) with AAD, and slower heart rate at ER (Exp(B) 0.977; CI 0.961~0.992, p=0.004) and later timing of ER (Exp(B) 1.017; CI 1.002~1.031, p=0.021) after RFCA were independent predictors for LR. We used IC AAD (36.7%) or amiodarone (AMD;46.9%). SR restoration rate were 70.1% in class IC and 64.5% in AMD (p=0.664) within 15.2±34.3 days. PeAF (Exp(B) 5.924, CI 1.292~27.153, p=0.022) and LR (Exp(B) 9.042, CI 2.017~40.527, p=0.004) were independent predictor of failed SR conversion with AMD. The proportions of AT in recurred ECG were 31.5% in ER and 37.3% in LR, and AAD responsiveness of AT (65.0%) was not different to AF (69.0%, p=0.612). Conclusion: Slower heart rate at ER and later ER were predictors for LR. Overall AAD responsiveness was 67.6% after RFCA of AF, but the patients with LR and PeAF were predictors for poor responsiveness to AMD.

KW - anti-arrhythmic drug

KW - atrial fibrillation

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