PE3-049 The Relationship between Internal Cardioversion Threshold or Post-Cardioversion Sinus Node Recovery Time and Atrial Structural or Autonomic Neural Remodeling in Persistent Atrial Fibrillation

Junbeom Park, Hoyoun Won, Hee Sun Mun, Jin Wee, Jaemin Shim, Jae Sun Uhm, Hye Jin Hwang, Jong Youn Kim, Boyoung Joung, Moon Houng Lee, Hui Nam Pak

Research output: Contribution to journalArticle

Abstract

Background: We hypothesized that cardioversion (CV) threshold and post-CV sinus node recovery time (PC-SNRT) are related with cardiac autonomic nerve function or atrial structural remodeling in persistent atrial fibrillation (PeAF). Methods: We included 74 patients with PeAF (62males, 54.8±10.5years old) who underwent radiofrequency catheter ablation (RFCA) and maintained sinus rhythm at the time of 3rd month Holter without taking any anti-arrhythmic drug or beta-blocker. At the beginning of RFCA, we delivered internal CV 2, 3, 5, 7, and 10J serially, and measured CV threshold and PC-SNRT. Results: 1. The patients with CHADS2 score>=1 showed higher CV threshold than those with 0 (8.3 ±2.1J vs. 6.2±2.5J, p=0.034). 2. CV threshold of the patients with left atrial(LA) volume>=120mL was significantly higher than those of patients with<120mL(8.2±2.2J vs. 6.4±2.7J, p=0.034). 3. PC-SNRT of the patients with LA-AP diameter (>=45mm) by echocardiography were significantly longer than that of the patients with<45mm (1422.2±1031.7ms vs. 1060.2±448.2ms, p=0.05). 4. PC-SNRT was correlated with 3rd month heart rate variability(HRV) including SDNN (R=0.400, p=0.005), HF (R=0.480, p=0.001), but not related with clinical recurrence of AF after RFCA. Conclusion: Both CV threshold and PC-SNRT were significantly greater in patients with atrial structural remodeling, but were not related with clinical outcome of RFCA in PeAF.

Original languageEnglish
Number of pages1
JournalJournal of Arrhythmia
Volume27
DOIs
Publication statusPublished - 2011 Jan 1
Externally publishedYes

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Electric Countershock
Sinoatrial Node
Atrial Fibrillation
Catheter Ablation
Atrial Remodeling
Autonomic Pathways
Anti-Arrhythmia Agents
Echocardiography
Heart Rate
Recurrence
Pharmaceutical Preparations

Keywords

  • cardioversion
  • persistent atrial fibrillation
  • sinus recovery time

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

PE3-049 The Relationship between Internal Cardioversion Threshold or Post-Cardioversion Sinus Node Recovery Time and Atrial Structural or Autonomic Neural Remodeling in Persistent Atrial Fibrillation. / Park, Junbeom; Won, Hoyoun; Mun, Hee Sun; Wee, Jin; Shim, Jaemin; Uhm, Jae Sun; Hwang, Hye Jin; Kim, Jong Youn; Joung, Boyoung; Lee, Moon Houng; Pak, Hui Nam.

In: Journal of Arrhythmia, Vol. 27, 01.01.2011.

Research output: Contribution to journalArticle

Park, Junbeom ; Won, Hoyoun ; Mun, Hee Sun ; Wee, Jin ; Shim, Jaemin ; Uhm, Jae Sun ; Hwang, Hye Jin ; Kim, Jong Youn ; Joung, Boyoung ; Lee, Moon Houng ; Pak, Hui Nam. / PE3-049 The Relationship between Internal Cardioversion Threshold or Post-Cardioversion Sinus Node Recovery Time and Atrial Structural or Autonomic Neural Remodeling in Persistent Atrial Fibrillation. In: Journal of Arrhythmia. 2011 ; Vol. 27.
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abstract = "Background: We hypothesized that cardioversion (CV) threshold and post-CV sinus node recovery time (PC-SNRT) are related with cardiac autonomic nerve function or atrial structural remodeling in persistent atrial fibrillation (PeAF). Methods: We included 74 patients with PeAF (62males, 54.8±10.5years old) who underwent radiofrequency catheter ablation (RFCA) and maintained sinus rhythm at the time of 3rd month Holter without taking any anti-arrhythmic drug or beta-blocker. At the beginning of RFCA, we delivered internal CV 2, 3, 5, 7, and 10J serially, and measured CV threshold and PC-SNRT. Results: 1. The patients with CHADS2 score>=1 showed higher CV threshold than those with 0 (8.3 ±2.1J vs. 6.2±2.5J, p=0.034). 2. CV threshold of the patients with left atrial(LA) volume>=120mL was significantly higher than those of patients with<120mL(8.2±2.2J vs. 6.4±2.7J, p=0.034). 3. PC-SNRT of the patients with LA-AP diameter (>=45mm) by echocardiography were significantly longer than that of the patients with<45mm (1422.2±1031.7ms vs. 1060.2±448.2ms, p=0.05). 4. PC-SNRT was correlated with 3rd month heart rate variability(HRV) including SDNN (R=0.400, p=0.005), HF (R=0.480, p=0.001), but not related with clinical recurrence of AF after RFCA. Conclusion: Both CV threshold and PC-SNRT were significantly greater in patients with atrial structural remodeling, but were not related with clinical outcome of RFCA in PeAF.",
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T1 - PE3-049 The Relationship between Internal Cardioversion Threshold or Post-Cardioversion Sinus Node Recovery Time and Atrial Structural or Autonomic Neural Remodeling in Persistent Atrial Fibrillation

AU - Park, Junbeom

AU - Won, Hoyoun

AU - Mun, Hee Sun

AU - Wee, Jin

AU - Shim, Jaemin

AU - Uhm, Jae Sun

AU - Hwang, Hye Jin

AU - Kim, Jong Youn

AU - Joung, Boyoung

AU - Lee, Moon Houng

AU - Pak, Hui Nam

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Y1 - 2011/1/1

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AB - Background: We hypothesized that cardioversion (CV) threshold and post-CV sinus node recovery time (PC-SNRT) are related with cardiac autonomic nerve function or atrial structural remodeling in persistent atrial fibrillation (PeAF). Methods: We included 74 patients with PeAF (62males, 54.8±10.5years old) who underwent radiofrequency catheter ablation (RFCA) and maintained sinus rhythm at the time of 3rd month Holter without taking any anti-arrhythmic drug or beta-blocker. At the beginning of RFCA, we delivered internal CV 2, 3, 5, 7, and 10J serially, and measured CV threshold and PC-SNRT. Results: 1. The patients with CHADS2 score>=1 showed higher CV threshold than those with 0 (8.3 ±2.1J vs. 6.2±2.5J, p=0.034). 2. CV threshold of the patients with left atrial(LA) volume>=120mL was significantly higher than those of patients with<120mL(8.2±2.2J vs. 6.4±2.7J, p=0.034). 3. PC-SNRT of the patients with LA-AP diameter (>=45mm) by echocardiography were significantly longer than that of the patients with<45mm (1422.2±1031.7ms vs. 1060.2±448.2ms, p=0.05). 4. PC-SNRT was correlated with 3rd month heart rate variability(HRV) including SDNN (R=0.400, p=0.005), HF (R=0.480, p=0.001), but not related with clinical recurrence of AF after RFCA. Conclusion: Both CV threshold and PC-SNRT were significantly greater in patients with atrial structural remodeling, but were not related with clinical outcome of RFCA in PeAF.

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