Percutaneous coronary intervention for acute myocardial infarction in elderly patients with renal dysfunction: Results from the korea acute myocardial infarction registry

Sang Yeob Lim, Eun Hui Bae, Joon Seok Choi, Chang Seong Kim, Seong Kwon Ma, Youngkeun Ahn, Myung Ho Jeong, Weon Kim, Jong Shin Woo, Young Jo Kim, Myeong Chan Cho, Chong Jin Kim, Soo Wan Kim

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Abstract

This study aimed to evaluate the effects of percutaneous coronary intervention (PCI) on short- and long-term major adverse cardiac events (MACE) in elderly (> 75 yr old) acute myocardial infarction (AMI) patients with renal dysfunction. As part of Korea AMI Registry (KAMIR), elderly patients with AMI and renal dysfunction (GFR < 60 mL/min) received either medical (n = 439) or PCI (n = 1,019) therapy. Primary end point was in-hospital death. Secondary end point was MACE during a 1 month and 1 yr follow-up. PCI group showed a significantly lower incidence of in-hospital death (20.0% vs 14.3%, P = 0.006). Short-term and long-term MACE rates were higher in medical therapy group (31.9% vs 19.0%; 57.7% vs 31.3%, P < 0.001), and this difference was mainly attributed to cardiac death (29.3% vs 17.6%; 51.9% vs 25.0%, P < 0.001). MACE-free survival time after adjustment was also higher in PCI group on short-term (hazard ratio, 0.67; confidence interval, 0.45-0.98; P = 0.037) and long-term follow-up (hazard ratio, 0.61, confidence interval, 0.45-0.83; P = 0.002). In elderly AMI patients with renal dysfunction, PCI therapy yields favorable in-hospital and short-term and long-term MACE-free survival

Original languageEnglish
Pages (from-to)1027-1033
Number of pages7
JournalJournal of Korean Medical Science
Volume28
Issue number7
DOIs
Publication statusPublished - 2013 Jul 1

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Keywords

  • Acute myocardial infarction
  • Elderly
  • Major adverse cardiac event
  • Percutaneous coronary intervention
  • Renal dysfunction

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lim, S. Y., Bae, E. H., Choi, J. S., Kim, C. S., Ma, S. K., Ahn, Y., Jeong, M. H., Kim, W., Woo, J. S., Kim, Y. J., Cho, M. C., Kim, C. J., & Kim, S. W. (2013). Percutaneous coronary intervention for acute myocardial infarction in elderly patients with renal dysfunction: Results from the korea acute myocardial infarction registry. Journal of Korean Medical Science, 28(7), 1027-1033. https://doi.org/10.3346/jkms.2013.28.7.1027