Peripheral bone involvement of intravascular large B-cell lymphoma on 99mTc-MDP bone scan and 18F-FDG PET/CT

Sun Young Oh, Gi Jeong Cheon, Eugene Jeong, Sinae Lee, Tae Gyu Park, Kisoo Pahk, Jae-Gol Choe

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2 Citations (Scopus)


A 64-year-old man was admitted for evaluation of recently developed anemia and bone pain. The bone scan showed diffusely active lesions in the peripheral bones, symmetrically. Interestingly, F-FDG PET/CT revealed the hypermetabolic changes in the peripheral bones as well as the internal organs. Biopsy of bone marrow confirmed the diagnosis of intravascular B-cell lymphoma. After the 3 cycles of R-CHOP chemotherapy, F-FDG PET/CT showed improvement of the previous hypermetabolic lesions, suggesting good response. Intravascular B-cell lymphoma is a rare and aggressive variant of diffuse large cell lymphoma characterized by proliferation of malignant cells within the vascular lumina.

Original languageEnglish
Pages (from-to)810-811
Number of pages2
JournalClinical Nuclear Medicine
Issue number8
Publication statusPublished - 2012 Aug 1



  • Bone scan
  • intravascular B-cell lymphoma

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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