Pesticide exposure and lung cancer mortality in Leningrad province in Russia

Won Jin Lee, Andrea Baccarelli, Maria Tretiakova, Sergey Gorbanev, Alexei Lomtev, Irina Klimkina, Vladimir Tchibissov, Olga Averkina, Mustafa Dosemeci

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

This study was carried out to examine the association between pesticide exposure and lung cancer mortality. We conducted an autopsy based case-control study in Leningrad Province in Russia. A total of 540 lung cancer cases and 582 controls were identified among subjects who had died in the hospitals of the Leningrad province between 1993 and 1998. Using work history records, we assessed exposure to pesticide at the level of industry and job title. Unconditional logistic regression was used to calculate adjusted odds ratio for pesticide exposure and lung cancer mortality. There was no association between ever exposure to pesticide and lung cancer mortality overall (odds ratio = 1.06, 95% confidence interval = 0.82-1.36) and in both men (odds ratio = 1.11, 95% confidence interval = 0.84-1.46) and women (odds ratio = 0.74, 95% confidence interval = 0.37-1.46). We observed no statistically significant odds ratio by duration of pesticide exposure, intensity of pesticide exposure, and cumulative pesticide exposures with lung cancer mortality in both smokers and nonsmokers. Odds ratio also did not differ when the analysis was restricted to individuals who had exposure data with high confidence scores. Our findings suggest no associations between pesticide exposures and mortality of lung cancer in the population of the Leningrad province in Russia that deserves further evaluation.

Original languageEnglish
Pages (from-to)412-416
Number of pages5
JournalEnvironment International
Volume32
Issue number3
DOIs
Publication statusPublished - 2006 Jan 1

Fingerprint

Russia
Pesticides
cancer
Lung Neoplasms
pesticide
mortality
Mortality
Odds Ratio
confidence interval
Confidence Intervals
province
exposure
Case-Control Studies
Autopsy
Industry
Logistic Models
logistics
industry
Population
history

Keywords

  • Lung neoplasms
  • Occupation
  • Pesticide exposure
  • Russia

ASJC Scopus subject areas

  • Environmental Science(all)

Cite this

Lee, W. J., Baccarelli, A., Tretiakova, M., Gorbanev, S., Lomtev, A., Klimkina, I., ... Dosemeci, M. (2006). Pesticide exposure and lung cancer mortality in Leningrad province in Russia. Environment International, 32(3), 412-416. https://doi.org/10.1016/j.envint.2005.10.001

Pesticide exposure and lung cancer mortality in Leningrad province in Russia. / Lee, Won Jin; Baccarelli, Andrea; Tretiakova, Maria; Gorbanev, Sergey; Lomtev, Alexei; Klimkina, Irina; Tchibissov, Vladimir; Averkina, Olga; Dosemeci, Mustafa.

In: Environment International, Vol. 32, No. 3, 01.01.2006, p. 412-416.

Research output: Contribution to journalArticle

Lee, WJ, Baccarelli, A, Tretiakova, M, Gorbanev, S, Lomtev, A, Klimkina, I, Tchibissov, V, Averkina, O & Dosemeci, M 2006, 'Pesticide exposure and lung cancer mortality in Leningrad province in Russia', Environment International, vol. 32, no. 3, pp. 412-416. https://doi.org/10.1016/j.envint.2005.10.001
Lee, Won Jin ; Baccarelli, Andrea ; Tretiakova, Maria ; Gorbanev, Sergey ; Lomtev, Alexei ; Klimkina, Irina ; Tchibissov, Vladimir ; Averkina, Olga ; Dosemeci, Mustafa. / Pesticide exposure and lung cancer mortality in Leningrad province in Russia. In: Environment International. 2006 ; Vol. 32, No. 3. pp. 412-416.
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