Peutz-Jeghers syndrome with multiple genital tract tumors and breast cancer: A case report with a review of literatures

Seung Hun Song, Jae Kwan Lee, Ho Suk Saw, Sang Yong Choi, Bum Hwan Koo, Aeree Kim, Bum Woo Yeom, Insun Kim

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

We report here on the multiple genital tract neoplasms in a 41-yr-old Korean woman with Peutz-Jeghers Syndrome (PJS). The patient presented with lower abdominal pain. Her previous medical history was PJS and breast cancer. Pelvic ultrasound showed a multilocular cyst at the right adnexal region, diagnosed as bilateral ovarian mucinous borderline tumors. An ovarian sex cord tumor with annular tubules was incidentally diagnosed together with a minimal deviation adenocarcinoma of the uterine cervix and mucinous metaplasia of both the Fallopian tubal mucosa and the endometrium. Although the cases of multiple genital tract tumors with PJS has rarely been reported, the present case appears to be the first in Korea in which the PJS syndrome was complicated by multiple genital tract tumors and infiltrating carcinoma of the breast. The clinical significance of the multiple genital tract tumors and breast cancer associated with PJS is reviewed.

Original languageEnglish
Pages (from-to)752-757
Number of pages6
JournalJournal of Korean Medical Science
Volume21
Issue number4
Publication statusPublished - 2006 Aug 15

Keywords

  • Breast
  • Cervix Uteri
  • Fallopian Tubes
  • Ovary
  • Peutz-Jeghers Syndrome

ASJC Scopus subject areas

  • Medicine(all)

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