Photoprotective effects of a formulation containing tannase-converted green tea extract against UVB-induced oxidative stress in hairless mice

Yang Hee Hong, Eun Young Jung, Kwang Soon Shin, Tae Young Kim, Kwang Won Yu, Un Jae Chang, Hyung Joo Suh

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Ultraviolet B (UVB) irradiation may induce the acceleration of skin aging. The purpose of this study was to develop an effective formulation containing tannase-converted green tea extract (FTGE) to inhibit UVB-induced oxidative damage. Significant (p∈<∈0.05) prevention of the reduced form of glutathione (GSH) depletion was observed in mice treated with FTGE. The hydrogen peroxide levels of mice treated with FTGE were similar to those of UVB non-irradiated mice. No significant difference was observed between No UVB control and FTGE mice. Also, mice treated with FTGE had significant (p∈<∈0.05) decreases in thiobarbituric acid-reactive substance levels by lipid peroxidation compared with No UVB control mice. Our data suggest that this formulation may be effective in protecting skin from UVB photodamage.

Original languageEnglish
Pages (from-to)165-175
Number of pages11
JournalApplied Biochemistry and Biotechnology
Volume166
Issue number1
DOIs
Publication statusPublished - 2012 Jan

Keywords

  • Formulation
  • Green tea
  • Oxidative stress
  • Photoprotection
  • Tannase

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology

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