Physiological characteristics and anti-obesity effect of lactobacillus plantarum Q180 isolated from feces

Sun Young Park, Seong A. Cho, Sae Hun Kim, Sang Dong Lim

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Obesity is strongly associated with several metabolic and chronic diseases and has become a major public health problem of worldwide concern. This study aimed to investigate the physiological characteristics and anti-obesity effects of Lactobacillus plantarum Q180. Lactobacillus plantarum Q180 was isolated from the faces of healthy adults and found to have a lipase inhibitory activity of 83.61±2.32% and inhibited adipocyte differentiation of 3T3-L1 cells (14.63±1.37%) at a concentration of 100 μg/mL. The strain was investigated for its physiological characteristics. The optimum growth temperature of L. plantarum Q180 was 37°C. Lactobacillus plantarum Q180 showed higher sensitivity to novobiocin in a comparison of fifteen different antibiotics and showed the highest resistance to rifampicin, polymyxin B and vancomycin. The strain showed higher β-galactosidase and N-acetyl-β-glucosaminidase activities. It also did not produce carcinogenic enzymes such as β-glucuronidase. The survival rate of L. plantarum Q180 in MRS broth containing 0.3% bile was 97.8%. Moreover, the strain showed a 97.2% survival rate after incubation for 3 h in pH 2.0. Lactobacillus plantarum Q180 was displayed resistance to Escherichia coli, Salmonella Typhimurium and Staphylococcus aureus with rates of 55.6%, 38.0% and 47.6%, respectively. These results demonstrate that L. plantarum Q180 has potential as a probiotic with anti-obesity effects.

Original languageEnglish
Pages (from-to)647-655
Number of pages9
JournalKorean Journal for Food Science of Animal Resources
Volume34
Issue number5
DOIs
Publication statusPublished - 2014 Oct 1

Fingerprint

Lactobacillus plantarum
Feces
obesity
Obesity
feces
survival rate
Galactosidases
Novobiocin
3T3-L1 Cells
polymyxin B
galactosidases
Hexosaminidases
novobiocin
Polymyxin B
rifampicin
vancomycin
Glucuronidase
Metabolic Diseases
Probiotics
metabolic diseases

Keywords

  • Anti-adipogenic activity
  • Anti-lipase activity
  • Lactobacillus plantarum
  • Physiological characteristics

ASJC Scopus subject areas

  • Food Science
  • Animal Science and Zoology

Cite this

Physiological characteristics and anti-obesity effect of lactobacillus plantarum Q180 isolated from feces. / Park, Sun Young; Cho, Seong A.; Kim, Sae Hun; Lim, Sang Dong.

In: Korean Journal for Food Science of Animal Resources, Vol. 34, No. 5, 01.10.2014, p. 647-655.

Research output: Contribution to journalArticle

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