Plasmon resonance energy transfer sp\ectroscopy (PRET)

Yeonho Choi, Taewook Kang, Gang L. Liu, Yitao Long, Luke P. Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

We demonstrate that gold nanoparticles (GNPs) with self-assembled monolayer (SAM) can function as all-optical nanoscale biomolecular detectors that monitor in situ resonant biomolecules, such as Cytochrome c. By tethering resonant biomolecules to Au nanoprobes, the binding events of Cytochrome c onto 50-nm Au nanoprobes yield characteristic spectral dips in scattering spectra of Au nanoprobes due to plasmon resonance energy transfer (PRET). The quenching dip depth of the single nanoprobe spectrum is found to be a function of incubation time (t) and concentration of Cytochrome c, which provides a real-time and nanoscale measurement and quantification of Cytochrome c.

Original languageEnglish
Title of host publicationProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
EditorsJean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin
PublisherChemical and Biological Microsystems Society
Pages1610-1612
Number of pages3
ISBN (Electronic)9780979806407
Publication statusPublished - 2007
Externally publishedYes
Event11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France
Duration: 2007 Oct 72007 Oct 11

Publication series

NameProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Conference

Conference11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
CountryFrance
CityParis
Period07/10/707/10/11

Keywords

  • Cytochrome C
  • Gold Nanoparticle
  • Plasmonic Resonance Energy Transfer
  • Rayleigh Scattering

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Choi, Y., Kang, T., Liu, G. L., Long, Y., & Lee, L. P. (2007). Plasmon resonance energy transfer sp\ectroscopy (PRET). In J-L. Viovy, P. Tabeling, S. Descroix, & L. Malaquin (Eds.), Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 (pp. 1610-1612). (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007). Chemical and Biological Microsystems Society.