Poikiloderma vasculare atrophicans showing features of ashy dermatosis in the beginning

Jiehyun Jeon, Joo Ha Kim, Jae Woo Ahn, Hae Jun Song

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Poikiloderma vasculare atrophicans (PVA) is a rare poikilodermatous variant of early-stage mycosis fungoides characterized by generalized poikiloderma, atrophy, mottled dyspigmentation, and telangiectasia. In 2001, a 14-year-old male presented with asymptomatic brownish-gray polymorphic macules throughout the body with flexural accentuation. A skin biopsy showed increased melanophages with focal hydropic changes. Ashy dermatosis was considered a possible diagnosis. In 2005, the lesions began to show darkening and lichenification in the lower part of the trunk. In 2011, his skin showed definite poikilodermatous changes, and a biopsy showed band-like inflammatory infiltrations of atypical lymphocytes, epidermal atrophy, and epidermotropism of predominantly CD4-CD8+ atypical T cells. In addition, results of T-cell receptor gene rearrangement analysis were positive. Based on the aforementioned findings, he was diagnosed with PVA. If a patient shows long-standing and progressive hyperpigmentary skin changes, periodic follow- up and repeated skin biopsies are recommended to determine the underlying condition. (Ann Dermatol 27(2) 197∼ 200, 2015).

Original languageEnglish
Pages (from-to)197-200
Number of pages4
JournalAnnals of Dermatology
Volume27
Issue number2
DOIs
Publication statusPublished - 2015 Apr 1

Keywords

  • CD4
  • CD4-CD8 ratio
  • CD8
  • Mycosis fungoides
  • Poikiloderma
  • T-lymphocytes

ASJC Scopus subject areas

  • Dermatology

Fingerprint Dive into the research topics of 'Poikiloderma vasculare atrophicans showing features of ashy dermatosis in the beginning'. Together they form a unique fingerprint.

  • Cite this