Poikiloderma vasculare atrophicans showing features of ashy dermatosis in the beginning

Jiehyun Jeon, Joo Ha Kim, Jae Woo Ahn, Hae Jun Song

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Poikiloderma vasculare atrophicans (PVA) is a rare poikilodermatous variant of early-stage mycosis fungoides characterized by generalized poikiloderma, atrophy, mottled dyspigmentation, and telangiectasia. In 2001, a 14-year-old male presented with asymptomatic brownish-gray polymorphic macules throughout the body with flexural accentuation. A skin biopsy showed increased melanophages with focal hydropic changes. Ashy dermatosis was considered a possible diagnosis. In 2005, the lesions began to show darkening and lichenification in the lower part of the trunk. In 2011, his skin showed definite poikilodermatous changes, and a biopsy showed band-like inflammatory infiltrations of atypical lymphocytes, epidermal atrophy, and epidermotropism of predominantly CD4-CD8+ atypical T cells. In addition, results of T-cell receptor gene rearrangement analysis were positive. Based on the aforementioned findings, he was diagnosed with PVA. If a patient shows long-standing and progressive hyperpigmentary skin changes, periodic follow- up and repeated skin biopsies are recommended to determine the underlying condition. (Ann Dermatol 27(2) 197∼ 200, 2015).

Original languageEnglish
Pages (from-to)197-200
Number of pages4
JournalAnnals of Dermatology
Volume27
Issue number2
DOIs
Publication statusPublished - 2015 Jan 1

Fingerprint

Skin Diseases
Skin
Biopsy
Atrophy
T-Lymphocyte Gene Rearrangement
T-Cell Receptor Genes
Telangiectasis
Mycosis Fungoides
Edema
Lymphocytes
T-Lymphocytes

Keywords

  • CD4
  • CD4-CD8 ratio
  • CD8
  • Mycosis fungoides
  • Poikiloderma
  • T-lymphocytes

ASJC Scopus subject areas

  • Dermatology

Cite this

Poikiloderma vasculare atrophicans showing features of ashy dermatosis in the beginning. / Jeon, Jiehyun; Kim, Joo Ha; Ahn, Jae Woo; Song, Hae Jun.

In: Annals of Dermatology, Vol. 27, No. 2, 01.01.2015, p. 197-200.

Research output: Contribution to journalArticle

@article{9d436652c68442ebab50d4ab39b8c172,
title = "Poikiloderma vasculare atrophicans showing features of ashy dermatosis in the beginning",
abstract = "Poikiloderma vasculare atrophicans (PVA) is a rare poikilodermatous variant of early-stage mycosis fungoides characterized by generalized poikiloderma, atrophy, mottled dyspigmentation, and telangiectasia. In 2001, a 14-year-old male presented with asymptomatic brownish-gray polymorphic macules throughout the body with flexural accentuation. A skin biopsy showed increased melanophages with focal hydropic changes. Ashy dermatosis was considered a possible diagnosis. In 2005, the lesions began to show darkening and lichenification in the lower part of the trunk. In 2011, his skin showed definite poikilodermatous changes, and a biopsy showed band-like inflammatory infiltrations of atypical lymphocytes, epidermal atrophy, and epidermotropism of predominantly CD4-CD8+ atypical T cells. In addition, results of T-cell receptor gene rearrangement analysis were positive. Based on the aforementioned findings, he was diagnosed with PVA. If a patient shows long-standing and progressive hyperpigmentary skin changes, periodic follow- up and repeated skin biopsies are recommended to determine the underlying condition. (Ann Dermatol 27(2) 197∼ 200, 2015).",
keywords = "CD4, CD4-CD8 ratio, CD8, Mycosis fungoides, Poikiloderma, T-lymphocytes",
author = "Jiehyun Jeon and Kim, {Joo Ha} and Ahn, {Jae Woo} and Song, {Hae Jun}",
year = "2015",
month = "1",
day = "1",
doi = "10.5021/ad.2015.27.2.197",
language = "English",
volume = "27",
pages = "197--200",
journal = "Annals of Dermatology",
issn = "1013-9087",
publisher = "Korean Dermatological Association",
number = "2",

}

TY - JOUR

T1 - Poikiloderma vasculare atrophicans showing features of ashy dermatosis in the beginning

AU - Jeon, Jiehyun

AU - Kim, Joo Ha

AU - Ahn, Jae Woo

AU - Song, Hae Jun

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Poikiloderma vasculare atrophicans (PVA) is a rare poikilodermatous variant of early-stage mycosis fungoides characterized by generalized poikiloderma, atrophy, mottled dyspigmentation, and telangiectasia. In 2001, a 14-year-old male presented with asymptomatic brownish-gray polymorphic macules throughout the body with flexural accentuation. A skin biopsy showed increased melanophages with focal hydropic changes. Ashy dermatosis was considered a possible diagnosis. In 2005, the lesions began to show darkening and lichenification in the lower part of the trunk. In 2011, his skin showed definite poikilodermatous changes, and a biopsy showed band-like inflammatory infiltrations of atypical lymphocytes, epidermal atrophy, and epidermotropism of predominantly CD4-CD8+ atypical T cells. In addition, results of T-cell receptor gene rearrangement analysis were positive. Based on the aforementioned findings, he was diagnosed with PVA. If a patient shows long-standing and progressive hyperpigmentary skin changes, periodic follow- up and repeated skin biopsies are recommended to determine the underlying condition. (Ann Dermatol 27(2) 197∼ 200, 2015).

AB - Poikiloderma vasculare atrophicans (PVA) is a rare poikilodermatous variant of early-stage mycosis fungoides characterized by generalized poikiloderma, atrophy, mottled dyspigmentation, and telangiectasia. In 2001, a 14-year-old male presented with asymptomatic brownish-gray polymorphic macules throughout the body with flexural accentuation. A skin biopsy showed increased melanophages with focal hydropic changes. Ashy dermatosis was considered a possible diagnosis. In 2005, the lesions began to show darkening and lichenification in the lower part of the trunk. In 2011, his skin showed definite poikilodermatous changes, and a biopsy showed band-like inflammatory infiltrations of atypical lymphocytes, epidermal atrophy, and epidermotropism of predominantly CD4-CD8+ atypical T cells. In addition, results of T-cell receptor gene rearrangement analysis were positive. Based on the aforementioned findings, he was diagnosed with PVA. If a patient shows long-standing and progressive hyperpigmentary skin changes, periodic follow- up and repeated skin biopsies are recommended to determine the underlying condition. (Ann Dermatol 27(2) 197∼ 200, 2015).

KW - CD4

KW - CD4-CD8 ratio

KW - CD8

KW - Mycosis fungoides

KW - Poikiloderma

KW - T-lymphocytes

UR - http://www.scopus.com/inward/record.url?scp=84925687331&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84925687331&partnerID=8YFLogxK

U2 - 10.5021/ad.2015.27.2.197

DO - 10.5021/ad.2015.27.2.197

M3 - Article

AN - SCOPUS:84925687331

VL - 27

SP - 197

EP - 200

JO - Annals of Dermatology

JF - Annals of Dermatology

SN - 1013-9087

IS - 2

ER -