TY - JOUR
T1 - Pollen-food allergy syndrome in Korean pollinosis patients
T2 - A nationwide survey
AU - and Work Group for Rhinitis, the Korean Academy of Asthma, Allergy and Clinical Immunology
AU - Kim, Mi Ae
AU - Kim, Dong Kyu
AU - Yang, Hyeon Jong
AU - Yoo, Young
AU - Ahn, Youngmin
AU - Park, Hae Sim
AU - Lee, Hyun Jong
AU - Jeong, Yi Yeong
AU - Kim, Bong Seong
AU - Bae, Woo Yong
AU - Jang, An Soo
AU - Park, Yang
AU - Koh, Young Il
AU - Lee, Jaechun
AU - Lim, Dae Hyun
AU - Kim, Jeong Hee
AU - Lee, Sang Min
AU - Kim, Yong Min
AU - Jun, Young Joon
AU - Kim, Hyo Yeol
AU - Kim, Yunsun
AU - Choi, Jeong Hee
N1 - Funding Information:
This study was supported by a grant from the Korean Academy of Asthma, Allergy, and Clinical Immunology (2016).
Publisher Copyright:
© 2018 The Korean Academy of Asthma, Allergy and Clinical Immunology · The Korean Academy of Pediatric Allergy and Respiratory Disease.
PY - 2018/11/1
Y1 - 2018/11/1
N2 - Purpose: Pollen-food allergy syndrome (PFAS) is an immunoglobulin E (IgE)-mediated allergy in pollinosis patients caused by raw fruits and vegetables and is the most common food allergy in adults. However, there has been no nationwide study on PFAS in Korea. In this study, we investigated the prevalence and clinical characteristics of PFAS in Korea. Methods: Twenty-two investigators participated in this study, in which patients with allergic rhinoconjunctivitis and/or bronchial asthma with pollen allergy were enrolled. The questionnaires included demographic characteristics, a list of fruits and vegetables, and clinical manifestations of food allergy. Pollen allergy was diagnosed by skin prick test and/or measurement of the serum level of specific IgE. Results: A total of 648 pollinosis patients were enrolled. The prevalence of PFAS was 41.7% (n = 270). PFAS patients exhibited cutaneous (43.0%), respiratory (20.0%), cardiovascular (3.7%) or neurologic symptoms (4.8%) in addition to oropharyngeal symptoms. Anaphylaxis was noted in 8.9% of the PFAS patients. Seventy types of foods were linked to PFAS; e.g., peach (48.5%), apple (46.7%), kiwi (30.4%), peanut (17.4%), plum (16.3%), chestnut (14.8%), pineapple (13.7%), walnut (14.1%), Korean melon (12.6%), tomato (11.9%), melon (11.5%) and apricot (10.7%). Korean foods such as taro/taro stem (8.9%), ginseong (8.2%), perilla leaf (4.4%), bellflower root (4.4%), crown daisy (3.0%), deodeok (3.3%), kudzu root (3.0%) and lotus root (2.6%) were also linked to PFAS. Conclusions: This was the first nationwide study of PFAS in Korea. The prevalence of PFAS was 41.7%, and 8.9% of the PFAS patients had anaphylaxis. These results will provide clinically useful information to physicians.
AB - Purpose: Pollen-food allergy syndrome (PFAS) is an immunoglobulin E (IgE)-mediated allergy in pollinosis patients caused by raw fruits and vegetables and is the most common food allergy in adults. However, there has been no nationwide study on PFAS in Korea. In this study, we investigated the prevalence and clinical characteristics of PFAS in Korea. Methods: Twenty-two investigators participated in this study, in which patients with allergic rhinoconjunctivitis and/or bronchial asthma with pollen allergy were enrolled. The questionnaires included demographic characteristics, a list of fruits and vegetables, and clinical manifestations of food allergy. Pollen allergy was diagnosed by skin prick test and/or measurement of the serum level of specific IgE. Results: A total of 648 pollinosis patients were enrolled. The prevalence of PFAS was 41.7% (n = 270). PFAS patients exhibited cutaneous (43.0%), respiratory (20.0%), cardiovascular (3.7%) or neurologic symptoms (4.8%) in addition to oropharyngeal symptoms. Anaphylaxis was noted in 8.9% of the PFAS patients. Seventy types of foods were linked to PFAS; e.g., peach (48.5%), apple (46.7%), kiwi (30.4%), peanut (17.4%), plum (16.3%), chestnut (14.8%), pineapple (13.7%), walnut (14.1%), Korean melon (12.6%), tomato (11.9%), melon (11.5%) and apricot (10.7%). Korean foods such as taro/taro stem (8.9%), ginseong (8.2%), perilla leaf (4.4%), bellflower root (4.4%), crown daisy (3.0%), deodeok (3.3%), kudzu root (3.0%) and lotus root (2.6%) were also linked to PFAS. Conclusions: This was the first nationwide study of PFAS in Korea. The prevalence of PFAS was 41.7%, and 8.9% of the PFAS patients had anaphylaxis. These results will provide clinically useful information to physicians.
KW - Food allergy
KW - Pollen
KW - Pollen-food allergy syndrome
UR - http://www.scopus.com/inward/record.url?scp=85054996969&partnerID=8YFLogxK
U2 - 10.4168/aair.2018.10.6.648
DO - 10.4168/aair.2018.10.6.648
M3 - Article
AN - SCOPUS:85054996969
SN - 2092-7355
VL - 10
SP - 648
EP - 661
JO - Allergy, Asthma and Immunology Research
JF - Allergy, Asthma and Immunology Research
IS - 6
ER -