Polymeric Nanocomplex Encapsulating Iron Oxide Nanoparticles in Constant Size for Controllable Magnetic Field Reactivity

Sang Hun Chun, Seung Won Shin, Lunjakorn Amornkitbamrung, So Yeon Ahn, Ji Soo Yuk, Sang Jun Sim, Dan Luo, Soong Ho Um

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The magnetic properties of nanoparticles make them ideal for using in various applications, especially in biomedical applications. However, the magnetic force generated by a single nanoparticle is low. Herein, we describe the development of nanocomplexes (size of 100 nm) of many iron oxide nanoparticles (IONPs) encapsulated in poly(lactic-co-glycolic acid) (PLGA) using the simple method of emulsion solvent evaporation. The response of the IONP-encapsulated PLGA nanocomplexes (IPNs) to an external magnetic field could be controlled by modifying the amount of IONPs loaded into each nanocomplex. In a constant size of IPNs, larger loading numbers of IONPs resulted in more rapid responses to a magnetic field. In addition, nanocomplexes were coated with a silica layer to facilitate the addition of fluorescent dyes. This allowed visualization of the responses of the IPNs to an applied magnetic field corresponding to the IONP loading amount. We envision that these versatile, easy-to-fabricate IPNs with controllable magnetism will have important potential applications in diverse fields.

Original languageEnglish
Pages (from-to)12827-12833
Number of pages7
JournalLangmuir
Volume34
Issue number43
DOIs
Publication statusPublished - 2018 Oct 30

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Spectroscopy
  • Electrochemistry

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    Chun, S. H., Shin, S. W., Amornkitbamrung, L., Ahn, S. Y., Yuk, J. S., Sim, S. J., Luo, D., & Um, S. H. (2018). Polymeric Nanocomplex Encapsulating Iron Oxide Nanoparticles in Constant Size for Controllable Magnetic Field Reactivity. Langmuir, 34(43), 12827-12833. https://doi.org/10.1021/acs.langmuir.7b04143