Polymeric nanoparticles for protein kinase activity

Jong Ho Kim, Seulki Lee, Kwangmeyung Kim, Hyesung Jeon, Rang Woon Park, In San Kim, Kuiwon Choi, Ick Chan Kwon

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

Nanoparticles were prepared from poly-ion complexes, possessing both PEI-FITC-(PKA-specific substrate) (kemptide) and PAA-TRITC, which produce intermolecular FRET; the nanoparticles were dissociated by phosphorylation, presented a strong FITC intensity and can be applied to high-throughput screening for large chemical libraries, for drug discovery of kinase inhibitors.

Original languageEnglish
Pages (from-to)1346-1348
Number of pages3
JournalChemical Communications
Issue number13
DOIs
Publication statusPublished - 2007

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Fingerprint

Dive into the research topics of 'Polymeric nanoparticles for protein kinase activity'. Together they form a unique fingerprint.

Cite this