Polymeric nanoparticles for protein kinase activity

Jong Ho Kim, Seulki Lee, Kwangmeyung Kim, Hyesung Jeon, Rang Woon Park, In San Kim, Kuiwon Choi, Ick Chan Kwon

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Nanoparticles were prepared from poly-ion complexes, possessing both PEI-FITC-(PKA-specific substrate) (kemptide) and PAA-TRITC, which produce intermolecular FRET; the nanoparticles were dissociated by phosphorylation, presented a strong FITC intensity and can be applied to high-throughput screening for large chemical libraries, for drug discovery of kinase inhibitors.

Original languageEnglish
Pages (from-to)1346-1348
Number of pages3
JournalChemical Communications
Issue number13
DOIs
Publication statusPublished - 2007

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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  • Cite this

    Kim, J. H., Lee, S., Kim, K., Jeon, H., Park, R. W., Kim, I. S., Choi, K., & Kwon, I. C. (2007). Polymeric nanoparticles for protein kinase activity. Chemical Communications, (13), 1346-1348. https://doi.org/10.1039/b612773h