Polymeric Nanoparticles in Cancer Therapy

Heebeom Koo, Ji Young Yhee, Ick Chan Kwon, Kwangmeyung Kim, Ramesh Subbiah

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Chemotherapy is the clinical treatment of disease with chemical drugs, and has been researched and performed over several hundreds of years. Compared to surgery, it is regarded as noninvasive, relatively cheaper, easy for public assessment, and less dangerous. However, there are also some risks and side effects when drugs are not localized in the target disease site, but in another normal site, because most drugs can change the biological metabolism even in healthy tissues. Therefore, the efcient and accurate delivery of drugs to the target disease tissue and cells is highly important in chemotherapy. An ideal drug delivery system (DDS) can provide expected clinical outcomes with a minimum amount of drugs so that its efciency is valuable from the economic point of view. In addition, it can reduce the unintended side effect resulting from drug accumulation in normal healthy tissues. To realize this system, many biomedical researchers have made efforts for nding more efcient delivery methods or carriers and optimizing these systems (Xie et al. 2010).

Original languageEnglish
Title of host publicationNanobiomaterials
Subtitle of host publicationDevelopment and Applications
PublisherCRC Press
Pages109-150
Number of pages42
ISBN (Electronic)9781439876428
ISBN (Print)9781138072589
DOIs
Publication statusPublished - 2013 Jan 1
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Engineering(all)
  • Materials Science(all)

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