Poor-quality sleep is associated with metabolic syndrome in Korean adults

Junyong Lee, Youn Seon Choi, Young Jin Jeong, Juneyoung Lee, Jung Hyun Kim, Su Hyun Kim, Sook Haeng Joe, Tae Hee Jeon

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Sleep disorder and metabolic syndrome (MetS) are important health-related problems. Recently, sleep duration has decreased among Korean adults. In this study, we examined whether sleep quality is associated with MetS by analyzing 301 subjects, aged 20 years or over, without acute and severe illness who visited three primary care clinics. Sleep duration, sleep quality and the risk of sleep-related breathing disorder (SRBD) were assessed with a standardized sleeping-estimating instrument. MetS was defined according to the modified diagnostic criteria of the National Cholesterol Education Program Adult Treatment Panel-III using the Korean abdominal obesity definition. In the multiple logistic regression analysis, compared with the 7-hour sleep group, the adjusted odds ratios (ORs) of the ≤ 5- and ≥ 9-hour sleep groups for MetS were 4.89 and 5.98, respectively. Compared with the good-sleep quality and low-SRBD risk groups, the adjusted ORs of the poor-quality sleep and high-SRBD risk groups were 3.83 and 1.92, respectively (p < 0.05). In the ≤ 5- and ≥ 9-hour sleep groups, the prevalence of elevated triglyceride and high HOMA-IR was higher (p = 0.069). In the poor-quality sleep group, the prevalence of abdominal obesity, elevated triglyceride, low HDL cholesterol, high fasting insulin and high HOMA-IR were higher. In the high-SRBD risk group, the prevalence of abdominal obesity, obesity and elevated triglyceride were higher (p < 0.05). Overall, the ≤ 5- or ≥ 9-hour sleep duration, poor-quality sleep and high-SRBD risk are related with the high prevalence of MetS, perhaps through elevated insulin-resistance resulting from adiposity.

Original languageEnglish
Pages (from-to)281-291
Number of pages11
JournalTohoku Journal of Experimental Medicine
Volume231
Issue number4
DOIs
Publication statusPublished - 2013 Dec 13

Fingerprint

Sleep
Respiration
Abdominal Obesity
Triglycerides
Odds Ratio
Insulin
Adiposity
HDL Cholesterol
Regression analysis
Insulin Resistance
Fasting
Primary Health Care
Logistics
Obesity
Logistic Models
Cholesterol
Regression Analysis
Education

Keywords

  • Adiposity
  • Insulin-resistance
  • Korea
  • Metabolic syndrome
  • Sleep

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Poor-quality sleep is associated with metabolic syndrome in Korean adults. / Lee, Junyong; Choi, Youn Seon; Jeong, Young Jin; Lee, Juneyoung; Kim, Jung Hyun; Kim, Su Hyun; Joe, Sook Haeng; Jeon, Tae Hee.

In: Tohoku Journal of Experimental Medicine, Vol. 231, No. 4, 13.12.2013, p. 281-291.

Research output: Contribution to journalArticle

Lee, Junyong ; Choi, Youn Seon ; Jeong, Young Jin ; Lee, Juneyoung ; Kim, Jung Hyun ; Kim, Su Hyun ; Joe, Sook Haeng ; Jeon, Tae Hee. / Poor-quality sleep is associated with metabolic syndrome in Korean adults. In: Tohoku Journal of Experimental Medicine. 2013 ; Vol. 231, No. 4. pp. 281-291.
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