Poor renal uptake of Tc-99m DMSA and Tc-99m MDP in a patient with Fanconi syndrome and near normal glomerular filtration rate

Eun Kim Sang Eun Kim, Tae Cho Jong Tae Cho, Soo Lee Dong Soo Lee, J. K. Chung, S. Kim, Chul Lee Myung Chul Lee, Sang Lee Jung Sang Lee, C. S. Koh

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11 Citations (Scopus)

Abstract

The authors present a patient with Fanconi syndrome who demonstrate poor renal uptake of Tc-99m DMSA and high urinary concentration of the tracer. Tc- 99m DTPA imaging was normal and the creatinine clearance was only minimally decreased. These findings suggest that Tc-99m DMSA may be accumulated in the kidney by glomerular filtration and subsequent tubular reabsorption. A Tc- 99m MDP bone scan showed faint renal uptake, as well as diffuse high skeletal uptake, particularly in the spine, demonstrating that the metabolic bone disease associated with Fanconi syndrome can be one of the causes of poor renal visualization on a bone scan.

Original languageEnglish
Pages (from-to)215-219
Number of pages5
JournalClinical nuclear medicine
Volume20
Issue number3
DOIs
Publication statusPublished - 1995
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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