Porous TiO 2 films on Ti implants for controlled release of tetracycline-hydrochloride (TCH)

Cheol Min Han, Eun Jung Lee, Hyoun Ee Kim, Young-Hag Koh, Jun Hyeog Jang

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Micro- and nano-porous TiO 2 films were created on the surface of Ti implants using micro-arc oxidation and anodic titanium oxide treatments, respectively, to load a sol-gel derived silica xerogel for the controlled release of the antibiotic drug, tetracycline-hydrochloride (TCH). When the silica xerogel containing TCH was loaded into porous TiO 2 films, a very high drug loading efficiency was observed compared to when it was loaded in Ti implants without a TiO 2 film. Moreover, TCH was released in a controlled manner for up to 7 days.

Original languageEnglish
Pages (from-to)8074-8076
Number of pages3
JournalThin Solid Films
Volume519
Issue number22
DOIs
Publication statusPublished - 2011 Sep 1

Fingerprint

tetracyclines
hydrochlorides
Tetracycline
Xerogels
xerogels
Silicon Dioxide
drugs
Silica
silicon dioxide
antibiotics
Titanium oxides
Antibiotics
titanium oxides
Pharmaceutical Preparations
Sol-gels
arcs
gels
Anti-Bacterial Agents
Oxidation
oxidation

Keywords

  • Anodic titanium oxide
  • Controlled drug release
  • Micro-arc oxidation
  • Silica xerogel

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Materials Chemistry
  • Metals and Alloys
  • Surfaces, Coatings and Films
  • Surfaces and Interfaces

Cite this

Porous TiO 2 films on Ti implants for controlled release of tetracycline-hydrochloride (TCH). / Han, Cheol Min; Lee, Eun Jung; Kim, Hyoun Ee; Koh, Young-Hag; Jang, Jun Hyeog.

In: Thin Solid Films, Vol. 519, No. 22, 01.09.2011, p. 8074-8076.

Research output: Contribution to journalArticle

Han, Cheol Min ; Lee, Eun Jung ; Kim, Hyoun Ee ; Koh, Young-Hag ; Jang, Jun Hyeog. / Porous TiO 2 films on Ti implants for controlled release of tetracycline-hydrochloride (TCH). In: Thin Solid Films. 2011 ; Vol. 519, No. 22. pp. 8074-8076.
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