Abstract
OBJECTIVE: Features of the metabolic syndrome such as abdominal adiposity, insulin resistance, and dyslipidemia develop with the transition from pre- to postmenopausal status in women. We investigated the effects of postmenopausal status on the prevalence of the metabolic syndrome according to years since menopause. DESIGN: We studied 1,002 women, 618 premenopausal and 384 postmenopausal, who participated in annual health examinations at Anam Hospital in Seoul, Korea. RESULTS: Using multivariate logistic regression analysis, we determined that postmenopausal status was an independent risk factor for the metabolic syndrome. Moreover, after controlling for age and body mass index, postmenopausal women had an increased risk of the metabolic syndrome (odds ratio, 2.93; 95% CI, 1.62-5.33) and the abnormalities of its individual components. The risk for the metabolic syndrome increased up to 14 years since menopause, then decreased. For its individual components, postmenopausal women with 5 to 9 years since menopause had the highest risk of high blood pressure; postmenopausal women with less than 5 years since menopause had an increased risk of abdominal obesity and high glucose. With 10 to 14 years since menopause, postmenopausal women had an increased risk of high triglycerides. CONCLUSIONS: Postmenopausal status is an independent risk factor for the metabolic syndrome and all of its individual components. The risk for the metabolic syndrome increased up to 14 years since menopause. In addition, postmenopausal status has effects during different periods since menopause for each of these components.
| Original language | English |
|---|---|
| Pages (from-to) | 524-529 |
| Number of pages | 6 |
| Journal | Menopause |
| Volume | 15 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2008 May |
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Keywords
- Menopause
- Metabolic syndrome
ASJC Scopus subject areas
- Obstetrics and Gynaecology
Cite this
Postmenopausal status according to years since menopause as an independent risk factor for the metabolic syndrome. / Cho, Geum-Joon; Hyun Lee, Jong; Park, Hyun-Tae; Shin, Jung-Ho; Hong, Soon Cheol; Kim, Tak; Hur, Jun Young; Wan Lee, Kyu; Kyun Park, Yong; Haeng Kim, Sun.
In: Menopause, Vol. 15, No. 3, 05.2008, p. 524-529.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Postmenopausal status according to years since menopause as an independent risk factor for the metabolic syndrome
AU - Cho, Geum-Joon
AU - Hyun Lee, Jong
AU - Park, Hyun-Tae
AU - Shin, Jung-Ho
AU - Hong, Soon Cheol
AU - Kim, Tak
AU - Hur, Jun Young
AU - Wan Lee, Kyu
AU - Kyun Park, Yong
AU - Haeng Kim, Sun
PY - 2008/5
Y1 - 2008/5
N2 - OBJECTIVE: Features of the metabolic syndrome such as abdominal adiposity, insulin resistance, and dyslipidemia develop with the transition from pre- to postmenopausal status in women. We investigated the effects of postmenopausal status on the prevalence of the metabolic syndrome according to years since menopause. DESIGN: We studied 1,002 women, 618 premenopausal and 384 postmenopausal, who participated in annual health examinations at Anam Hospital in Seoul, Korea. RESULTS: Using multivariate logistic regression analysis, we determined that postmenopausal status was an independent risk factor for the metabolic syndrome. Moreover, after controlling for age and body mass index, postmenopausal women had an increased risk of the metabolic syndrome (odds ratio, 2.93; 95% CI, 1.62-5.33) and the abnormalities of its individual components. The risk for the metabolic syndrome increased up to 14 years since menopause, then decreased. For its individual components, postmenopausal women with 5 to 9 years since menopause had the highest risk of high blood pressure; postmenopausal women with less than 5 years since menopause had an increased risk of abdominal obesity and high glucose. With 10 to 14 years since menopause, postmenopausal women had an increased risk of high triglycerides. CONCLUSIONS: Postmenopausal status is an independent risk factor for the metabolic syndrome and all of its individual components. The risk for the metabolic syndrome increased up to 14 years since menopause. In addition, postmenopausal status has effects during different periods since menopause for each of these components.
AB - OBJECTIVE: Features of the metabolic syndrome such as abdominal adiposity, insulin resistance, and dyslipidemia develop with the transition from pre- to postmenopausal status in women. We investigated the effects of postmenopausal status on the prevalence of the metabolic syndrome according to years since menopause. DESIGN: We studied 1,002 women, 618 premenopausal and 384 postmenopausal, who participated in annual health examinations at Anam Hospital in Seoul, Korea. RESULTS: Using multivariate logistic regression analysis, we determined that postmenopausal status was an independent risk factor for the metabolic syndrome. Moreover, after controlling for age and body mass index, postmenopausal women had an increased risk of the metabolic syndrome (odds ratio, 2.93; 95% CI, 1.62-5.33) and the abnormalities of its individual components. The risk for the metabolic syndrome increased up to 14 years since menopause, then decreased. For its individual components, postmenopausal women with 5 to 9 years since menopause had the highest risk of high blood pressure; postmenopausal women with less than 5 years since menopause had an increased risk of abdominal obesity and high glucose. With 10 to 14 years since menopause, postmenopausal women had an increased risk of high triglycerides. CONCLUSIONS: Postmenopausal status is an independent risk factor for the metabolic syndrome and all of its individual components. The risk for the metabolic syndrome increased up to 14 years since menopause. In addition, postmenopausal status has effects during different periods since menopause for each of these components.
KW - Menopause
KW - Metabolic syndrome
UR - http://www.scopus.com/inward/record.url?scp=43249124233&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=43249124233&partnerID=8YFLogxK
U2 - 10.1097/gme.0b013e3181559860
DO - 10.1097/gme.0b013e3181559860
M3 - Article
VL - 15
SP - 524
EP - 529
JO - Menopause
JF - Menopause
SN - 1072-3714
IS - 3
ER -