Potential probiotic properties of Lactococcus lactis NK34 isolated from jeotgal

Na Kyoung Lee, Ji Eun Noh, Gui Hun Choi, Eunju Park, Hyo-Ihl Chang, Cheol-Won Yun, Seung Wook Kim, Chang Won Kang, Yoh Chang Yoon, Hyun Dong Paik

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Strain NK34 was characterized for probiotic use. Strain NK34 was named Lactococcus lactis NK34 based on API 50 CHL kit results and 16S rDNA sequencing. L lactis NK34 was highly resistant to artificial gastric juice (pH 2.5) and artificial bile acid. Based on results from the API ZYM kit, 4 enzymes were produced. L. lactis NK34 was resistant to all antibiotics tested except for 10 μg/mL roxithromycin and 10 μg/mL erythromycin. The cholesterol-lowering effect of L. lactis NK34 was about 46.9%. Concentrations of interleukin (IL)-1α in the 20× concentrated supernatant of L. lactis NK34 was about 361 pg/mL. L. lactis NK34 was also found to inhibit the growth of colon cancer cells due to MNNG-induced DNA damage. These results demonstrate the potential of L. lactis NK34 as a health-promoting probiotic.

Original languageEnglish
Pages (from-to)843-847
Number of pages5
JournalFood Science and Biotechnology
Volume16
Issue number5
Publication statusPublished - 2007 Dec 1

Fingerprint

Lactococcus lactis
Probiotics
probiotics
roxithromycin
Roxithromycin
gastric juice
Methylnitronitrosoguanidine
health promotion
Gastric Juice
cholesteremic effect
erythromycin
interleukin-1
bile acids
Erythromycin
Ribosomal DNA
Bile Acids and Salts
colorectal neoplasms
Interleukin-1
DNA damage
Colonic Neoplasms

Keywords

  • Cholesterol-lowering activity
  • DNA damage
  • Immunolstimulating activity
  • Jeotgal
  • Lactococcus lactis
  • Probiotics

ASJC Scopus subject areas

  • Food Science
  • Biotechnology
  • Applied Microbiology and Biotechnology

Cite this

Lee, N. K., Noh, J. E., Choi, G. H., Park, E., Chang, H-I., Yun, C-W., ... Paik, H. D. (2007). Potential probiotic properties of Lactococcus lactis NK34 isolated from jeotgal. Food Science and Biotechnology, 16(5), 843-847.

Potential probiotic properties of Lactococcus lactis NK34 isolated from jeotgal. / Lee, Na Kyoung; Noh, Ji Eun; Choi, Gui Hun; Park, Eunju; Chang, Hyo-Ihl; Yun, Cheol-Won; Kim, Seung Wook; Kang, Chang Won; Yoon, Yoh Chang; Paik, Hyun Dong.

In: Food Science and Biotechnology, Vol. 16, No. 5, 01.12.2007, p. 843-847.

Research output: Contribution to journalArticle

Lee, NK, Noh, JE, Choi, GH, Park, E, Chang, H-I, Yun, C-W, Kim, SW, Kang, CW, Yoon, YC & Paik, HD 2007, 'Potential probiotic properties of Lactococcus lactis NK34 isolated from jeotgal', Food Science and Biotechnology, vol. 16, no. 5, pp. 843-847.
Lee, Na Kyoung ; Noh, Ji Eun ; Choi, Gui Hun ; Park, Eunju ; Chang, Hyo-Ihl ; Yun, Cheol-Won ; Kim, Seung Wook ; Kang, Chang Won ; Yoon, Yoh Chang ; Paik, Hyun Dong. / Potential probiotic properties of Lactococcus lactis NK34 isolated from jeotgal. In: Food Science and Biotechnology. 2007 ; Vol. 16, No. 5. pp. 843-847.
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