Potential probiotic properties of Lactococcus lactis NK34 isolated from jeotgal

Na Kyoung Lee, Ji Eun Noh, Gui Hun Choi, Eunju Park, Hyo Ihl Chang, Cheol Won Yun, Seung Wook Kim, Chang Won Kang, Yoh Chang Yoon, Hyun Dong Paik

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Strain NK34 was characterized for probiotic use. Strain NK34 was named Lactococcus lactis NK34 based on API 50 CHL kit results and 16S rDNA sequencing. L lactis NK34 was highly resistant to artificial gastric juice (pH 2.5) and artificial bile acid. Based on results from the API ZYM kit, 4 enzymes were produced. L. lactis NK34 was resistant to all antibiotics tested except for 10 μg/mL roxithromycin and 10 μg/mL erythromycin. The cholesterol-lowering effect of L. lactis NK34 was about 46.9%. Concentrations of interleukin (IL)-1α in the 20× concentrated supernatant of L. lactis NK34 was about 361 pg/mL. L. lactis NK34 was also found to inhibit the growth of colon cancer cells due to MNNG-induced DNA damage. These results demonstrate the potential of L. lactis NK34 as a health-promoting probiotic.

Original languageEnglish
Pages (from-to)843-847
Number of pages5
JournalFood Science and Biotechnology
Issue number5
Publication statusPublished - 2007


  • Cholesterol-lowering activity
  • DNA damage
  • Immunolstimulating activity
  • Jeotgal
  • Lactococcus lactis
  • Probiotics

ASJC Scopus subject areas

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology


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