Abstract
Objective To investigate the practice patterns of urologists in managing Korean men aged 40 years or younger with high serum prostate-specific antigen (PSA). Materials and Methods Data were collected from general health screenings conducted at 4 university hospitals between 2004 and 2012. Eligibility criteria were Korean men aged ≤40 years who were seen by urologists for high PSA (>2.5 ng/mL). After excluding individuals with chronic prostatitis and any infectious symptoms and/or signs, the practice patterns of urologists managing 237 eligible men were analyzed. Results The most common practice was observation after antibiotics (40.5%), followed by reassurance (38.4%), prostate biopsy (PBx) after antibiotics (11.8%), PBx after PSA follow-up (7.6%), and immediate PBx (1.7%). Antibiotics were prescribed empirically to 124 patients (52.3%). Of the entire patients, 145 of 237 (61.2%) had at least 1 follow-up PSA, and the follow-up PSA with median interval of 43 days (interquartile range, 26-149) was higher than initial PSA in 66 of 145 (45.5%). Of the 98 patients undergoing follow-up PSA after initial antibiotic treatment, 53 (54.1%) experienced a decline in PSA, whereas 45 (45.9%) experienced a rise in PSA. PBx was performed in 50 of 237 (21.1%), and only a single case (2%) of prostate cancer was diagnosed. Conclusion In managing men ≤40 years with high PSA, the most common practice pattern was observation after antibiotic treatment despite lack of evidences. Furthermore, 1 in 5 urologists performed PBx to rule out cancer. Given the very low prevalence of cancer in this age group, clear guidelines are needed for appropriate management and consistency of care.
| Original language | English |
|---|---|
| Pages (from-to) | 1339-1343 |
| Number of pages | 5 |
| Journal | Urology |
| Volume | 83 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2014 Jan 1 |
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Practice patterns of urologists in managing korean men aged 40 years or younger with high serum prostate-specific antigen levels. / Yoo, Dae Seon; Woo, Seung Hyo; Cho, Seok; Kang, Seok Ho; Kim, Sang Jin; Park, Sung Yul; Lee, Sang Hyub; Jeon, Seung Hyun; Park, Jinsung.
In: Urology, Vol. 83, No. 6, 01.01.2014, p. 1339-1343.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Practice patterns of urologists in managing korean men aged 40 years or younger with high serum prostate-specific antigen levels
AU - Yoo, Dae Seon
AU - Woo, Seung Hyo
AU - Cho, Seok
AU - Kang, Seok Ho
AU - Kim, Sang Jin
AU - Park, Sung Yul
AU - Lee, Sang Hyub
AU - Jeon, Seung Hyun
AU - Park, Jinsung
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Objective To investigate the practice patterns of urologists in managing Korean men aged 40 years or younger with high serum prostate-specific antigen (PSA). Materials and Methods Data were collected from general health screenings conducted at 4 university hospitals between 2004 and 2012. Eligibility criteria were Korean men aged ≤40 years who were seen by urologists for high PSA (>2.5 ng/mL). After excluding individuals with chronic prostatitis and any infectious symptoms and/or signs, the practice patterns of urologists managing 237 eligible men were analyzed. Results The most common practice was observation after antibiotics (40.5%), followed by reassurance (38.4%), prostate biopsy (PBx) after antibiotics (11.8%), PBx after PSA follow-up (7.6%), and immediate PBx (1.7%). Antibiotics were prescribed empirically to 124 patients (52.3%). Of the entire patients, 145 of 237 (61.2%) had at least 1 follow-up PSA, and the follow-up PSA with median interval of 43 days (interquartile range, 26-149) was higher than initial PSA in 66 of 145 (45.5%). Of the 98 patients undergoing follow-up PSA after initial antibiotic treatment, 53 (54.1%) experienced a decline in PSA, whereas 45 (45.9%) experienced a rise in PSA. PBx was performed in 50 of 237 (21.1%), and only a single case (2%) of prostate cancer was diagnosed. Conclusion In managing men ≤40 years with high PSA, the most common practice pattern was observation after antibiotic treatment despite lack of evidences. Furthermore, 1 in 5 urologists performed PBx to rule out cancer. Given the very low prevalence of cancer in this age group, clear guidelines are needed for appropriate management and consistency of care.
AB - Objective To investigate the practice patterns of urologists in managing Korean men aged 40 years or younger with high serum prostate-specific antigen (PSA). Materials and Methods Data were collected from general health screenings conducted at 4 university hospitals between 2004 and 2012. Eligibility criteria were Korean men aged ≤40 years who were seen by urologists for high PSA (>2.5 ng/mL). After excluding individuals with chronic prostatitis and any infectious symptoms and/or signs, the practice patterns of urologists managing 237 eligible men were analyzed. Results The most common practice was observation after antibiotics (40.5%), followed by reassurance (38.4%), prostate biopsy (PBx) after antibiotics (11.8%), PBx after PSA follow-up (7.6%), and immediate PBx (1.7%). Antibiotics were prescribed empirically to 124 patients (52.3%). Of the entire patients, 145 of 237 (61.2%) had at least 1 follow-up PSA, and the follow-up PSA with median interval of 43 days (interquartile range, 26-149) was higher than initial PSA in 66 of 145 (45.5%). Of the 98 patients undergoing follow-up PSA after initial antibiotic treatment, 53 (54.1%) experienced a decline in PSA, whereas 45 (45.9%) experienced a rise in PSA. PBx was performed in 50 of 237 (21.1%), and only a single case (2%) of prostate cancer was diagnosed. Conclusion In managing men ≤40 years with high PSA, the most common practice pattern was observation after antibiotic treatment despite lack of evidences. Furthermore, 1 in 5 urologists performed PBx to rule out cancer. Given the very low prevalence of cancer in this age group, clear guidelines are needed for appropriate management and consistency of care.
UR - http://www.scopus.com/inward/record.url?scp=84901625963&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84901625963&partnerID=8YFLogxK
U2 - 10.1016/j.urology.2014.02.014
DO - 10.1016/j.urology.2014.02.014
M3 - Article
C2 - 24726151
AN - SCOPUS:84901625963
VL - 83
SP - 1339
EP - 1343
JO - Urology
JF - Urology
SN - 0090-4295
IS - 6
ER -