Precautions for the use of Q-switched neodymium: yttrium-aluminium-garnet laser for treatment of melasma

Hwa Jung Ryu, Jeong Eun Kim, Il-Hwan Kim

Research output: Contribution to journalReview article

Abstract

Melasma is a common pigmentary disorder with therapeutic challenges. Laser toning, a repetitive treatment of skin with low fluence 1064-nm Q-switched neodymium:yttrium-aluminium-garnet laser, has been recently used for treatment of melasma in Asia. Its mechanism is based on the subcellular selective photothermolysis theory that low fluence Q-switched neodymium:yttrium-aluminium- garnet laser treatment influences only melanosomes without destroying the melanocytes. No response to treatment, rebound hyperpigmentation or mottled hypopigmentation has been reported during laser toning. Patients with increased vasculature and erythema are poor indicators for laser toning, and history of skin-coloring tattooing should always be determined prior to treatment due to risk of paradoxical darkening. Sensitive skin with erythema should be treated prior to laser toning in order to recover the skin barrier. It is important to use low fluence for laser toning, as high fluence with strong photoacoustic energy will disrupt the basement membrane, further aggravating melasma.

Original languageEnglish
Pages (from-to)667-679
Number of pages13
JournalExpert Review of Dermatology
Volume8
Issue number6
DOIs
Publication statusPublished - 2013 Nov 22

Fingerprint

Neodymium
Melanosis
Solid-State Lasers
Lasers
Skin
Erythema
Therapeutics
Tattooing
Hypopigmentation
Melanosomes
Hyperpigmentation
Melanocytes
Basement Membrane

Keywords

  • laser toning
  • melasma
  • Q-switched Nd:YAG
  • side effects

ASJC Scopus subject areas

  • Dermatology

Cite this

Precautions for the use of Q-switched neodymium : yttrium-aluminium-garnet laser for treatment of melasma. / Ryu, Hwa Jung; Kim, Jeong Eun; Kim, Il-Hwan.

In: Expert Review of Dermatology, Vol. 8, No. 6, 22.11.2013, p. 667-679.

Research output: Contribution to journalReview article

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