Predicting type 2 diabetes using Sasang constitutional medicine

Nam H. Cho, Jong Yeol Kim, Sung Soo Kim, Seung Ku Lee, Chol Shin

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Aims/Introduction: Sasang constitutional medicine (SCM) has existed in traditional Korean medicine for more than 100 years. SCM consists of four different types: So-Eum (SE), So-Yang (SY), Tae-Eum (TE) and Tae-Yang (TY). It is of great importance that the Sasang constitution type (SCT) be evaluated accurately and recognized by medical communities. Materials and Methods: From the Ansung-Ansan prospective cohort study, 10,038 participants were recruited from the years 2001-2002. Of 10,038 original participants, 2,460 participants underwent SCT evaluation. The Cox proportional hazard model was used to predict diabetes during the 10-year follow-up period. Results: During 10 years of follow up (22,007 person-years), 472 incidence cases (215/10,000 Incidence Density) of type 2 diabetes mellitus were documented. We identified that the TE group was significantly older, more obese, and had higher blood pressure, glucose metabolic values and lipid profiles levels. Relative risk (RR) and 95% confident intervals (CI) for type 2 diabetes were 1.696 (95% CI 1.204-2.39, P = 0.003) for TE when compared with the SE type. After controlling all potential confounders, the Cox proportional hazard model showed that RR was 1.635 (95% CI 1.111-2.406) in non-obese (body mass index <25) TE, and RR was 1.725 (95% CI 1.213-2.452) in obese (body mass index ≥25) TE when compared with the SE type. We did not find any differences when comparing SE and SY types. The findings shows that TE is a higher risk factor for type 2 Diabetes, independent of obesity level. Conclusions: The present study suggests that the TE type, independent of obesity level, is a strong risk factor of type 2 diabetes.

Original languageEnglish
Pages (from-to)525-532
Number of pages8
JournalJournal of Diabetes Investigation
Volume5
Issue number5
DOIs
Publication statusPublished - 2014 Jan 1

Fingerprint

Type 2 Diabetes Mellitus
Medicine
Constitution and Bylaws
Proportional Hazards Models
Korean Traditional Medicine
Body Mass Index
Obesity
Incidence
Blood Glucose
Cohort Studies
Prospective Studies
Hypertension
Lipids

Cite this

Predicting type 2 diabetes using Sasang constitutional medicine. / Cho, Nam H.; Kim, Jong Yeol; Kim, Sung Soo; Lee, Seung Ku; Shin, Chol.

In: Journal of Diabetes Investigation, Vol. 5, No. 5, 01.01.2014, p. 525-532.

Research output: Contribution to journalArticle

Cho, Nam H. ; Kim, Jong Yeol ; Kim, Sung Soo ; Lee, Seung Ku ; Shin, Chol. / Predicting type 2 diabetes using Sasang constitutional medicine. In: Journal of Diabetes Investigation. 2014 ; Vol. 5, No. 5. pp. 525-532.
@article{6ad1c428d87141a1a73c3eb1514245d4,
title = "Predicting type 2 diabetes using Sasang constitutional medicine",
abstract = "Aims/Introduction: Sasang constitutional medicine (SCM) has existed in traditional Korean medicine for more than 100 years. SCM consists of four different types: So-Eum (SE), So-Yang (SY), Tae-Eum (TE) and Tae-Yang (TY). It is of great importance that the Sasang constitution type (SCT) be evaluated accurately and recognized by medical communities. Materials and Methods: From the Ansung-Ansan prospective cohort study, 10,038 participants were recruited from the years 2001-2002. Of 10,038 original participants, 2,460 participants underwent SCT evaluation. The Cox proportional hazard model was used to predict diabetes during the 10-year follow-up period. Results: During 10 years of follow up (22,007 person-years), 472 incidence cases (215/10,000 Incidence Density) of type 2 diabetes mellitus were documented. We identified that the TE group was significantly older, more obese, and had higher blood pressure, glucose metabolic values and lipid profiles levels. Relative risk (RR) and 95{\%} confident intervals (CI) for type 2 diabetes were 1.696 (95{\%} CI 1.204-2.39, P = 0.003) for TE when compared with the SE type. After controlling all potential confounders, the Cox proportional hazard model showed that RR was 1.635 (95{\%} CI 1.111-2.406) in non-obese (body mass index <25) TE, and RR was 1.725 (95{\%} CI 1.213-2.452) in obese (body mass index ≥25) TE when compared with the SE type. We did not find any differences when comparing SE and SY types. The findings shows that TE is a higher risk factor for type 2 Diabetes, independent of obesity level. Conclusions: The present study suggests that the TE type, independent of obesity level, is a strong risk factor of type 2 diabetes.",
keywords = "Prospective study, Sasang constitutional medicine, Type 2 diabetes mellitus",
author = "Cho, {Nam H.} and Kim, {Jong Yeol} and Kim, {Sung Soo} and Lee, {Seung Ku} and Chol Shin",
year = "2014",
month = "1",
day = "1",
doi = "10.1111/jdi.12189",
language = "English",
volume = "5",
pages = "525--532",
journal = "Journal of Diabetes Investigation",
issn = "2040-1116",
publisher = "Blackwell Publishing Asia Pty Ltd",
number = "5",

}

TY - JOUR

T1 - Predicting type 2 diabetes using Sasang constitutional medicine

AU - Cho, Nam H.

AU - Kim, Jong Yeol

AU - Kim, Sung Soo

AU - Lee, Seung Ku

AU - Shin, Chol

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Aims/Introduction: Sasang constitutional medicine (SCM) has existed in traditional Korean medicine for more than 100 years. SCM consists of four different types: So-Eum (SE), So-Yang (SY), Tae-Eum (TE) and Tae-Yang (TY). It is of great importance that the Sasang constitution type (SCT) be evaluated accurately and recognized by medical communities. Materials and Methods: From the Ansung-Ansan prospective cohort study, 10,038 participants were recruited from the years 2001-2002. Of 10,038 original participants, 2,460 participants underwent SCT evaluation. The Cox proportional hazard model was used to predict diabetes during the 10-year follow-up period. Results: During 10 years of follow up (22,007 person-years), 472 incidence cases (215/10,000 Incidence Density) of type 2 diabetes mellitus were documented. We identified that the TE group was significantly older, more obese, and had higher blood pressure, glucose metabolic values and lipid profiles levels. Relative risk (RR) and 95% confident intervals (CI) for type 2 diabetes were 1.696 (95% CI 1.204-2.39, P = 0.003) for TE when compared with the SE type. After controlling all potential confounders, the Cox proportional hazard model showed that RR was 1.635 (95% CI 1.111-2.406) in non-obese (body mass index <25) TE, and RR was 1.725 (95% CI 1.213-2.452) in obese (body mass index ≥25) TE when compared with the SE type. We did not find any differences when comparing SE and SY types. The findings shows that TE is a higher risk factor for type 2 Diabetes, independent of obesity level. Conclusions: The present study suggests that the TE type, independent of obesity level, is a strong risk factor of type 2 diabetes.

AB - Aims/Introduction: Sasang constitutional medicine (SCM) has existed in traditional Korean medicine for more than 100 years. SCM consists of four different types: So-Eum (SE), So-Yang (SY), Tae-Eum (TE) and Tae-Yang (TY). It is of great importance that the Sasang constitution type (SCT) be evaluated accurately and recognized by medical communities. Materials and Methods: From the Ansung-Ansan prospective cohort study, 10,038 participants were recruited from the years 2001-2002. Of 10,038 original participants, 2,460 participants underwent SCT evaluation. The Cox proportional hazard model was used to predict diabetes during the 10-year follow-up period. Results: During 10 years of follow up (22,007 person-years), 472 incidence cases (215/10,000 Incidence Density) of type 2 diabetes mellitus were documented. We identified that the TE group was significantly older, more obese, and had higher blood pressure, glucose metabolic values and lipid profiles levels. Relative risk (RR) and 95% confident intervals (CI) for type 2 diabetes were 1.696 (95% CI 1.204-2.39, P = 0.003) for TE when compared with the SE type. After controlling all potential confounders, the Cox proportional hazard model showed that RR was 1.635 (95% CI 1.111-2.406) in non-obese (body mass index <25) TE, and RR was 1.725 (95% CI 1.213-2.452) in obese (body mass index ≥25) TE when compared with the SE type. We did not find any differences when comparing SE and SY types. The findings shows that TE is a higher risk factor for type 2 Diabetes, independent of obesity level. Conclusions: The present study suggests that the TE type, independent of obesity level, is a strong risk factor of type 2 diabetes.

KW - Prospective study

KW - Sasang constitutional medicine

KW - Type 2 diabetes mellitus

UR - http://www.scopus.com/inward/record.url?scp=84908603749&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84908603749&partnerID=8YFLogxK

U2 - 10.1111/jdi.12189

DO - 10.1111/jdi.12189

M3 - Article

AN - SCOPUS:84908603749

VL - 5

SP - 525

EP - 532

JO - Journal of Diabetes Investigation

JF - Journal of Diabetes Investigation

SN - 2040-1116

IS - 5

ER -