Predictive factors of major adverse cardiac events in acute myocardial infarction patients complicated by cardiogenic shock undergoing primary percutaneous coronary intervention

Sang Yup Lim, Myung Ho Jeong, Eun Hui Bae, Weon Kim, Ju Han Kim, Young Joon Hong, Hyung Wook Park, Dong Goo Kang, Yeon Sang Lee, Kye Hun Kim, Sang Hyun Lee, Kyung Ho Yun, Seo Na Hong, Jeong Gwan Cho, Young Keun Ahn, Jong Chun Park, Byoung Hee Ahn, Sang Hyung Kim, Jung Chaee Kang

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15 Citations (Scopus)

Abstract

Background: The aim of this study was to assess in-hospital mortality and major adverse cardiac events (MACE) during long-term clinical follow-up of patients who developed cardiogenic shock (CS) after acute myocardial infarction (AMI) and who underwent primary percutaneous coronary intervention (PCI). Methods and Results: The data from 147 patients with CS after AMI (61.7±10.4 years, M:F=156:99) who underwent primary PCI at Chonnam National University Hospital between January 1999 and December 2002 were analyzed: clinical characteristics, coronary angiographic findings and mortality during admission, and MACE during a 1-year clinical follow-up. Of the enrolled patients, 121 patients survived (group I, M:F=94:27) and 26 died (group II, M:F=14:12) during admission. By binary logistic regression analysis, in-hospital death was associated with low Thrombolysis In Myocardial Infarction (TIMI) flow after coronary revascularization (p=0.02, odds ratio (OR)=1.3). Eighty-nine patients (60.5%) survived without MACE during the 1-year clinical follow-up and MACE was associated with a C-reactive protein (CRP) of more than 1 mg/dl (p=0.002, OR =6.3) and low TIMI flow after coronary revascularization (p<0.001, OR =7.8). Conclusions: Primary PCI achieving TIMI 3 flow reduces in-hospital death in AMI with CS. High concentration of CRP and low TIMI flow are associated with MACE during long-term clinical follow-up.

Original languageEnglish
Pages (from-to)154-158
Number of pages5
JournalCirculation Journal
Volume69
Issue number2
DOIs
Publication statusPublished - 2005 Feb

Keywords

  • Coronary diseases
  • Myocardial infarction
  • Prognosis
  • Shock

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Lim, S. Y., Jeong, M. H., Bae, E. H., Kim, W., Kim, J. H., Hong, Y. J., Park, H. W., Kang, D. G., Lee, Y. S., Kim, K. H., Lee, S. H., Yun, K. H., Hong, S. N., Cho, J. G., Ahn, Y. K., Park, J. C., Ahn, B. H., Kim, S. H., & Kang, J. C. (2005). Predictive factors of major adverse cardiac events in acute myocardial infarction patients complicated by cardiogenic shock undergoing primary percutaneous coronary intervention. Circulation Journal, 69(2), 154-158. https://doi.org/10.1253/circj.69.154