Predictors for Late Recurrence of Atrial Fibrillation after Radiofrequency Catheter Ablation

Over 500 Cases Experience

Jaemin Shim, Hye Jin Hwang, Jong Youn Kim, Boyoung Joung, Moon Hyoung Lee, Hui Nam Pak

Research output: Contribution to journalArticle

Abstract

Background: Although radiofrequency Catheter ablation (RFCA) for atrial fibrillation (AF) is an effective rhythm control strategy, there is a substantial recurrence rate. We explored predictors of late recurrence (LR) of AF after RFCA with consistent strategy. Methods and Results: This study included 575 patients (77.1% male, 55.7 ±10.9 years old) with AF (65.7% paroxysmal AF) who underwent RFCA. We evaluated the clinical, electrophysiological, and multiple serologic parameters. Results: 1. During 12.4±5.9 months of follow-up, patients who experienced LR (21.8%) were older (55.0 ±10.9 vs. 57.7 ± 10.1 years old, p=0.019) and more likely to have persistent AF (50.4% vs. 29.4%, p<0.001) and greater LA volume (137.3±49.1 vs. 116.6±37.9 mL, p<0.001). 2. In patients with LR, both ablation time (6607±2631 vs. 5536±2344 sec, p<0.001) and procedure time (243±80 vs. 206±59 min, p<0.001) were prolonged, and early recurrence rate within 3 month of procedure was higher (63.0% vs. 26.4%, p<0.001). 3. In binary logistic regression analysis, LA volume (OR 1.008, CI 1.001-1.014, p=0.018), ablation time>5400 sec (OR 2.169, CI 1.170-4.022, p=0.014), and early recurrence (OR 3.870, CI 2.371-6.319, p<0.001) were the independent risk factors for LR of AF. Conclusion: In this single consistent strategy with over 500 AF ablation cases, the patients with LR had larger atrium, longer ablation time, and higher chance of early recurrence than those remained in sinus rhythm.

Original languageEnglish
Number of pages1
JournalJournal of Arrhythmia
Volume27
Issue number4
DOIs
Publication statusPublished - 2011 Jan 1
Externally publishedYes

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Catheter Ablation
Atrial Fibrillation
Recurrence

Keywords

  • atrial fibrillation
  • Catheter ablation
  • recurrence

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Predictors for Late Recurrence of Atrial Fibrillation after Radiofrequency Catheter Ablation : Over 500 Cases Experience. / Shim, Jaemin; Jin Hwang, Hye; Youn Kim, Jong; Joung, Boyoung; Lee, Moon Hyoung; Pak, Hui Nam.

In: Journal of Arrhythmia, Vol. 27, No. 4, 01.01.2011.

Research output: Contribution to journalArticle

Shim, Jaemin ; Jin Hwang, Hye ; Youn Kim, Jong ; Joung, Boyoung ; Lee, Moon Hyoung ; Pak, Hui Nam. / Predictors for Late Recurrence of Atrial Fibrillation after Radiofrequency Catheter Ablation : Over 500 Cases Experience. In: Journal of Arrhythmia. 2011 ; Vol. 27, No. 4.
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abstract = "Background: Although radiofrequency Catheter ablation (RFCA) for atrial fibrillation (AF) is an effective rhythm control strategy, there is a substantial recurrence rate. We explored predictors of late recurrence (LR) of AF after RFCA with consistent strategy. Methods and Results: This study included 575 patients (77.1{\%} male, 55.7 ±10.9 years old) with AF (65.7{\%} paroxysmal AF) who underwent RFCA. We evaluated the clinical, electrophysiological, and multiple serologic parameters. Results: 1. During 12.4±5.9 months of follow-up, patients who experienced LR (21.8{\%}) were older (55.0 ±10.9 vs. 57.7 ± 10.1 years old, p=0.019) and more likely to have persistent AF (50.4{\%} vs. 29.4{\%}, p<0.001) and greater LA volume (137.3±49.1 vs. 116.6±37.9 mL, p<0.001). 2. In patients with LR, both ablation time (6607±2631 vs. 5536±2344 sec, p<0.001) and procedure time (243±80 vs. 206±59 min, p<0.001) were prolonged, and early recurrence rate within 3 month of procedure was higher (63.0{\%} vs. 26.4{\%}, p<0.001). 3. In binary logistic regression analysis, LA volume (OR 1.008, CI 1.001-1.014, p=0.018), ablation time>5400 sec (OR 2.169, CI 1.170-4.022, p=0.014), and early recurrence (OR 3.870, CI 2.371-6.319, p<0.001) were the independent risk factors for LR of AF. Conclusion: In this single consistent strategy with over 500 AF ablation cases, the patients with LR had larger atrium, longer ablation time, and higher chance of early recurrence than those remained in sinus rhythm.",
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AU - Joung, Boyoung

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N2 - Background: Although radiofrequency Catheter ablation (RFCA) for atrial fibrillation (AF) is an effective rhythm control strategy, there is a substantial recurrence rate. We explored predictors of late recurrence (LR) of AF after RFCA with consistent strategy. Methods and Results: This study included 575 patients (77.1% male, 55.7 ±10.9 years old) with AF (65.7% paroxysmal AF) who underwent RFCA. We evaluated the clinical, electrophysiological, and multiple serologic parameters. Results: 1. During 12.4±5.9 months of follow-up, patients who experienced LR (21.8%) were older (55.0 ±10.9 vs. 57.7 ± 10.1 years old, p=0.019) and more likely to have persistent AF (50.4% vs. 29.4%, p<0.001) and greater LA volume (137.3±49.1 vs. 116.6±37.9 mL, p<0.001). 2. In patients with LR, both ablation time (6607±2631 vs. 5536±2344 sec, p<0.001) and procedure time (243±80 vs. 206±59 min, p<0.001) were prolonged, and early recurrence rate within 3 month of procedure was higher (63.0% vs. 26.4%, p<0.001). 3. In binary logistic regression analysis, LA volume (OR 1.008, CI 1.001-1.014, p=0.018), ablation time>5400 sec (OR 2.169, CI 1.170-4.022, p=0.014), and early recurrence (OR 3.870, CI 2.371-6.319, p<0.001) were the independent risk factors for LR of AF. Conclusion: In this single consistent strategy with over 500 AF ablation cases, the patients with LR had larger atrium, longer ablation time, and higher chance of early recurrence than those remained in sinus rhythm.

AB - Background: Although radiofrequency Catheter ablation (RFCA) for atrial fibrillation (AF) is an effective rhythm control strategy, there is a substantial recurrence rate. We explored predictors of late recurrence (LR) of AF after RFCA with consistent strategy. Methods and Results: This study included 575 patients (77.1% male, 55.7 ±10.9 years old) with AF (65.7% paroxysmal AF) who underwent RFCA. We evaluated the clinical, electrophysiological, and multiple serologic parameters. Results: 1. During 12.4±5.9 months of follow-up, patients who experienced LR (21.8%) were older (55.0 ±10.9 vs. 57.7 ± 10.1 years old, p=0.019) and more likely to have persistent AF (50.4% vs. 29.4%, p<0.001) and greater LA volume (137.3±49.1 vs. 116.6±37.9 mL, p<0.001). 2. In patients with LR, both ablation time (6607±2631 vs. 5536±2344 sec, p<0.001) and procedure time (243±80 vs. 206±59 min, p<0.001) were prolonged, and early recurrence rate within 3 month of procedure was higher (63.0% vs. 26.4%, p<0.001). 3. In binary logistic regression analysis, LA volume (OR 1.008, CI 1.001-1.014, p=0.018), ablation time>5400 sec (OR 2.169, CI 1.170-4.022, p=0.014), and early recurrence (OR 3.870, CI 2.371-6.319, p<0.001) were the independent risk factors for LR of AF. Conclusion: In this single consistent strategy with over 500 AF ablation cases, the patients with LR had larger atrium, longer ablation time, and higher chance of early recurrence than those remained in sinus rhythm.

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