Preeclampsia increases the incidence of postpartum cerebrovascular disease in Korean population

Yejin Park, Geum-Joon Cho, Log Young Kim, Tae Seon Lee, Min Jeong Oh, Young Han Kim

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: Multiple studies have been reported regarding preeclampsia as a possible risk factor of cerebrovascular disease (CVD). However, the correlation of preeclampsia and CVD, whether it is a cause-effect relationship or they are sharing common predisposing condition, is not well understood. Therefore, the aim of this study was to investigate the association between the preeclampsia during pregnancy and development of postpartum CVD. Methods: A total of 1,384,550 Korean women who had a delivery between January 1, 2010 and December 31, 2012, were enrolled. Women with the risk of CVD within 1 year prior to pregnancy were excluded based on the Charlson comorbidity index. Primary endpoint was the event of CVD within a year from delivery. After exclusion, 1,075,061 women were analyzed. Results: During the follow-up of 1 year postpartum, there were 25,577 preeclampsia out of 1,072,041 women without postpartum CVD (2.39%), and 121 of 3,020 women with postpartum CVD had preeclampsia before delivery (4.01%). In multivariate logistic regression analysis, women who had preeclampsia during pregnancy showed a higher risk for postpartum CVD (odds ratio, 1.64; 95% confidence interval, 1.37-1.98). Conclusion: The incidence of CVD after delivery was higher in women who had preeclampsia during pregnancy.

Original languageEnglish
Article numbere35
JournalJournal of Korean Medical Science
Volume33
Issue number6
DOIs
Publication statusPublished - 2018 Jan 1

Fingerprint

Cerebrovascular Disorders
Pre-Eclampsia
Postpartum Period
Incidence
Population
Pregnancy
Comorbidity
Logistic Models
Odds Ratio
Regression Analysis
Confidence Intervals

Keywords

  • Cerebrovascular disease
  • Insurance claim reporting
  • Korea
  • Postpartum period
  • Preeclampsia
  • Pregnancy

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Preeclampsia increases the incidence of postpartum cerebrovascular disease in Korean population. / Park, Yejin; Cho, Geum-Joon; Kim, Log Young; Lee, Tae Seon; Oh, Min Jeong; Kim, Young Han.

In: Journal of Korean Medical Science, Vol. 33, No. 6, e35, 01.01.2018.

Research output: Contribution to journalArticle

@article{d2b6e8d79d034190a9b2aef69028aa30,
title = "Preeclampsia increases the incidence of postpartum cerebrovascular disease in Korean population",
abstract = "Background: Multiple studies have been reported regarding preeclampsia as a possible risk factor of cerebrovascular disease (CVD). However, the correlation of preeclampsia and CVD, whether it is a cause-effect relationship or they are sharing common predisposing condition, is not well understood. Therefore, the aim of this study was to investigate the association between the preeclampsia during pregnancy and development of postpartum CVD. Methods: A total of 1,384,550 Korean women who had a delivery between January 1, 2010 and December 31, 2012, were enrolled. Women with the risk of CVD within 1 year prior to pregnancy were excluded based on the Charlson comorbidity index. Primary endpoint was the event of CVD within a year from delivery. After exclusion, 1,075,061 women were analyzed. Results: During the follow-up of 1 year postpartum, there were 25,577 preeclampsia out of 1,072,041 women without postpartum CVD (2.39{\%}), and 121 of 3,020 women with postpartum CVD had preeclampsia before delivery (4.01{\%}). In multivariate logistic regression analysis, women who had preeclampsia during pregnancy showed a higher risk for postpartum CVD (odds ratio, 1.64; 95{\%} confidence interval, 1.37-1.98). Conclusion: The incidence of CVD after delivery was higher in women who had preeclampsia during pregnancy.",
keywords = "Cerebrovascular disease, Insurance claim reporting, Korea, Postpartum period, Preeclampsia, Pregnancy",
author = "Yejin Park and Geum-Joon Cho and Kim, {Log Young} and Lee, {Tae Seon} and Oh, {Min Jeong} and Kim, {Young Han}",
year = "2018",
month = "1",
day = "1",
doi = "10.3346/jkms.2018.33.e35",
language = "English",
volume = "33",
journal = "Journal of Korean Medical Science",
issn = "1011-8934",
publisher = "Korean Academy of Medical Science",
number = "6",

}

TY - JOUR

T1 - Preeclampsia increases the incidence of postpartum cerebrovascular disease in Korean population

AU - Park, Yejin

AU - Cho, Geum-Joon

AU - Kim, Log Young

AU - Lee, Tae Seon

AU - Oh, Min Jeong

AU - Kim, Young Han

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Background: Multiple studies have been reported regarding preeclampsia as a possible risk factor of cerebrovascular disease (CVD). However, the correlation of preeclampsia and CVD, whether it is a cause-effect relationship or they are sharing common predisposing condition, is not well understood. Therefore, the aim of this study was to investigate the association between the preeclampsia during pregnancy and development of postpartum CVD. Methods: A total of 1,384,550 Korean women who had a delivery between January 1, 2010 and December 31, 2012, were enrolled. Women with the risk of CVD within 1 year prior to pregnancy were excluded based on the Charlson comorbidity index. Primary endpoint was the event of CVD within a year from delivery. After exclusion, 1,075,061 women were analyzed. Results: During the follow-up of 1 year postpartum, there were 25,577 preeclampsia out of 1,072,041 women without postpartum CVD (2.39%), and 121 of 3,020 women with postpartum CVD had preeclampsia before delivery (4.01%). In multivariate logistic regression analysis, women who had preeclampsia during pregnancy showed a higher risk for postpartum CVD (odds ratio, 1.64; 95% confidence interval, 1.37-1.98). Conclusion: The incidence of CVD after delivery was higher in women who had preeclampsia during pregnancy.

AB - Background: Multiple studies have been reported regarding preeclampsia as a possible risk factor of cerebrovascular disease (CVD). However, the correlation of preeclampsia and CVD, whether it is a cause-effect relationship or they are sharing common predisposing condition, is not well understood. Therefore, the aim of this study was to investigate the association between the preeclampsia during pregnancy and development of postpartum CVD. Methods: A total of 1,384,550 Korean women who had a delivery between January 1, 2010 and December 31, 2012, were enrolled. Women with the risk of CVD within 1 year prior to pregnancy were excluded based on the Charlson comorbidity index. Primary endpoint was the event of CVD within a year from delivery. After exclusion, 1,075,061 women were analyzed. Results: During the follow-up of 1 year postpartum, there were 25,577 preeclampsia out of 1,072,041 women without postpartum CVD (2.39%), and 121 of 3,020 women with postpartum CVD had preeclampsia before delivery (4.01%). In multivariate logistic regression analysis, women who had preeclampsia during pregnancy showed a higher risk for postpartum CVD (odds ratio, 1.64; 95% confidence interval, 1.37-1.98). Conclusion: The incidence of CVD after delivery was higher in women who had preeclampsia during pregnancy.

KW - Cerebrovascular disease

KW - Insurance claim reporting

KW - Korea

KW - Postpartum period

KW - Preeclampsia

KW - Pregnancy

UR - http://www.scopus.com/inward/record.url?scp=85042112808&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85042112808&partnerID=8YFLogxK

U2 - 10.3346/jkms.2018.33.e35

DO - 10.3346/jkms.2018.33.e35

M3 - Article

C2 - 29349936

AN - SCOPUS:85042112808

VL - 33

JO - Journal of Korean Medical Science

JF - Journal of Korean Medical Science

SN - 1011-8934

IS - 6

M1 - e35

ER -