Prenatal exposure to magnetic field increases dopamine levels in the striatum of offspring

Byung Cheon Lee, Guoying Bing, W. K J Chunchon, Joo M. Yoon, Kee Seok Kang, Eun J. Shin, Won-Ki Kim, Kwang H. Ko, Hyoung Chun Kim

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

1. The putative effects of prenatal exposure to magnetic field (MF) have recently received much interest. In the present study, mice were exposed to a MF of 50 mT during gestation (0-19 days). 2. After the exposure was terminated, mothers and offspring were returned to normal laboratory conditions. We then determined changes in striatal levels of dopamine (DA) and its metabolite 3,4-dihydroxyphenylacetic acid (DOPAC) in the offspring. 3. Our results indicate that prenatal exposure to MF increases levels of DA and DOPAC in the striatum at 4, 8 and 12 weeks postnatally.

Original languageEnglish
Pages (from-to)884-886
Number of pages3
JournalClinical and Experimental Pharmacology and Physiology
Volume28
Issue number11
DOIs
Publication statusPublished - 2001 Nov 29
Externally publishedYes

Keywords

  • Dopamine
  • Magnetic field
  • Perinatal effect
  • Striatum

ASJC Scopus subject areas

  • Physiology
  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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