Preoperative staging of rectal cancer

Comparison of 3-T high-field MRI and endorectal sonography

Ho Kyung Chun, Dongil Choi, Min Ju Kim, Jongmee Lee, Seong Hyeon Yun, Seung Hoon Kim, Soon Jin Lee, Chan Kyo Kim

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

OBJECTIVE. The aim of this study was to compare phased-array 3-T MRI and endorectal sonography in the preoperative staging of rectal cancer. MATERIALS AND METHODS. During an 8-month period, 24 patients with rectal cancer underwent both 3-T MRI performed with phased-array coils and 7.5- to 10-MHz endorectal sonography in the 3 weeks before surgical resection. Three radiologists independently reviewed the MR and endorectal sonographic images. The histopathologic findings in resected specimens were used to evaluate the sensitivities and specificities of these techniques for invasion of the muscularis propria and perirectal tissue and for lymph node involvement. Receiver operating characteristic (ROC) analysis was used to compare the diagnostic accuracies of the techniques. RESULTS. For muscularis propria invasion, the mean sensitivities of both MRI and endorectal sonography were 100%, and the mean specificities were 66.7% and 61.1%, respectively. The differences in the mean sensitivities and specificities were not statistically significant (p > 0.05 in each case). For perirectal tissue invasion, MRI and endorectal sonography had comparable sensitivities and specificities (91.1% vs 100%, 92.6% vs 81.5%; p > 0.05 in each case). They also had similar sensitivities and specificities for lymph node involvement (63.6% vs 57.6%, 92.3% vs 82.1%; p > 0.05 in each case). ROC curves for muscularis propria invasion and lymph node involvement showed no differences in diagnostic accuracy. The mean area under the ROC curve for endorectal sonography (A z = 0.996) for perirectal tissue invasion, however, showed higher accuracy than that of MRI (Az = 0.938, p = 0.028). CONCLUSION. The sensitivity, specificity, and accuracy of 3-T MRI were similar to those of endorectal sonography for muscularis propria invasion and lymph node involvement, but for perirectal tissue invasion, 3-T MRI was less accurate than endorectal sonography.

Original languageEnglish
Pages (from-to)1557-1562
Number of pages6
JournalAmerican Journal of Roentgenology
Volume187
Issue number6
DOIs
Publication statusPublished - 2006 Dec 1
Externally publishedYes

Fingerprint

Rectal Neoplasms
Ultrasonography
Sensitivity and Specificity
Lymph Nodes
ROC Curve

Keywords

  • Colon
  • MRI
  • Rectal cancer
  • Sonography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Preoperative staging of rectal cancer : Comparison of 3-T high-field MRI and endorectal sonography. / Chun, Ho Kyung; Choi, Dongil; Kim, Min Ju; Lee, Jongmee; Yun, Seong Hyeon; Kim, Seung Hoon; Lee, Soon Jin; Kim, Chan Kyo.

In: American Journal of Roentgenology, Vol. 187, No. 6, 01.12.2006, p. 1557-1562.

Research output: Contribution to journalArticle

Chun, Ho Kyung ; Choi, Dongil ; Kim, Min Ju ; Lee, Jongmee ; Yun, Seong Hyeon ; Kim, Seung Hoon ; Lee, Soon Jin ; Kim, Chan Kyo. / Preoperative staging of rectal cancer : Comparison of 3-T high-field MRI and endorectal sonography. In: American Journal of Roentgenology. 2006 ; Vol. 187, No. 6. pp. 1557-1562.
@article{d246631f60124d7bbcc700bae4827abb,
title = "Preoperative staging of rectal cancer: Comparison of 3-T high-field MRI and endorectal sonography",
abstract = "OBJECTIVE. The aim of this study was to compare phased-array 3-T MRI and endorectal sonography in the preoperative staging of rectal cancer. MATERIALS AND METHODS. During an 8-month period, 24 patients with rectal cancer underwent both 3-T MRI performed with phased-array coils and 7.5- to 10-MHz endorectal sonography in the 3 weeks before surgical resection. Three radiologists independently reviewed the MR and endorectal sonographic images. The histopathologic findings in resected specimens were used to evaluate the sensitivities and specificities of these techniques for invasion of the muscularis propria and perirectal tissue and for lymph node involvement. Receiver operating characteristic (ROC) analysis was used to compare the diagnostic accuracies of the techniques. RESULTS. For muscularis propria invasion, the mean sensitivities of both MRI and endorectal sonography were 100{\%}, and the mean specificities were 66.7{\%} and 61.1{\%}, respectively. The differences in the mean sensitivities and specificities were not statistically significant (p > 0.05 in each case). For perirectal tissue invasion, MRI and endorectal sonography had comparable sensitivities and specificities (91.1{\%} vs 100{\%}, 92.6{\%} vs 81.5{\%}; p > 0.05 in each case). They also had similar sensitivities and specificities for lymph node involvement (63.6{\%} vs 57.6{\%}, 92.3{\%} vs 82.1{\%}; p > 0.05 in each case). ROC curves for muscularis propria invasion and lymph node involvement showed no differences in diagnostic accuracy. The mean area under the ROC curve for endorectal sonography (A z = 0.996) for perirectal tissue invasion, however, showed higher accuracy than that of MRI (Az = 0.938, p = 0.028). CONCLUSION. The sensitivity, specificity, and accuracy of 3-T MRI were similar to those of endorectal sonography for muscularis propria invasion and lymph node involvement, but for perirectal tissue invasion, 3-T MRI was less accurate than endorectal sonography.",
keywords = "Colon, MRI, Rectal cancer, Sonography",
author = "Chun, {Ho Kyung} and Dongil Choi and Kim, {Min Ju} and Jongmee Lee and Yun, {Seong Hyeon} and Kim, {Seung Hoon} and Lee, {Soon Jin} and Kim, {Chan Kyo}",
year = "2006",
month = "12",
day = "1",
doi = "10.2214/AJR.05.1234",
language = "English",
volume = "187",
pages = "1557--1562",
journal = "American Journal of Roentgenology",
issn = "0361-803X",
publisher = "American Roentgen Ray Society",
number = "6",

}

TY - JOUR

T1 - Preoperative staging of rectal cancer

T2 - Comparison of 3-T high-field MRI and endorectal sonography

AU - Chun, Ho Kyung

AU - Choi, Dongil

AU - Kim, Min Ju

AU - Lee, Jongmee

AU - Yun, Seong Hyeon

AU - Kim, Seung Hoon

AU - Lee, Soon Jin

AU - Kim, Chan Kyo

PY - 2006/12/1

Y1 - 2006/12/1

N2 - OBJECTIVE. The aim of this study was to compare phased-array 3-T MRI and endorectal sonography in the preoperative staging of rectal cancer. MATERIALS AND METHODS. During an 8-month period, 24 patients with rectal cancer underwent both 3-T MRI performed with phased-array coils and 7.5- to 10-MHz endorectal sonography in the 3 weeks before surgical resection. Three radiologists independently reviewed the MR and endorectal sonographic images. The histopathologic findings in resected specimens were used to evaluate the sensitivities and specificities of these techniques for invasion of the muscularis propria and perirectal tissue and for lymph node involvement. Receiver operating characteristic (ROC) analysis was used to compare the diagnostic accuracies of the techniques. RESULTS. For muscularis propria invasion, the mean sensitivities of both MRI and endorectal sonography were 100%, and the mean specificities were 66.7% and 61.1%, respectively. The differences in the mean sensitivities and specificities were not statistically significant (p > 0.05 in each case). For perirectal tissue invasion, MRI and endorectal sonography had comparable sensitivities and specificities (91.1% vs 100%, 92.6% vs 81.5%; p > 0.05 in each case). They also had similar sensitivities and specificities for lymph node involvement (63.6% vs 57.6%, 92.3% vs 82.1%; p > 0.05 in each case). ROC curves for muscularis propria invasion and lymph node involvement showed no differences in diagnostic accuracy. The mean area under the ROC curve for endorectal sonography (A z = 0.996) for perirectal tissue invasion, however, showed higher accuracy than that of MRI (Az = 0.938, p = 0.028). CONCLUSION. The sensitivity, specificity, and accuracy of 3-T MRI were similar to those of endorectal sonography for muscularis propria invasion and lymph node involvement, but for perirectal tissue invasion, 3-T MRI was less accurate than endorectal sonography.

AB - OBJECTIVE. The aim of this study was to compare phased-array 3-T MRI and endorectal sonography in the preoperative staging of rectal cancer. MATERIALS AND METHODS. During an 8-month period, 24 patients with rectal cancer underwent both 3-T MRI performed with phased-array coils and 7.5- to 10-MHz endorectal sonography in the 3 weeks before surgical resection. Three radiologists independently reviewed the MR and endorectal sonographic images. The histopathologic findings in resected specimens were used to evaluate the sensitivities and specificities of these techniques for invasion of the muscularis propria and perirectal tissue and for lymph node involvement. Receiver operating characteristic (ROC) analysis was used to compare the diagnostic accuracies of the techniques. RESULTS. For muscularis propria invasion, the mean sensitivities of both MRI and endorectal sonography were 100%, and the mean specificities were 66.7% and 61.1%, respectively. The differences in the mean sensitivities and specificities were not statistically significant (p > 0.05 in each case). For perirectal tissue invasion, MRI and endorectal sonography had comparable sensitivities and specificities (91.1% vs 100%, 92.6% vs 81.5%; p > 0.05 in each case). They also had similar sensitivities and specificities for lymph node involvement (63.6% vs 57.6%, 92.3% vs 82.1%; p > 0.05 in each case). ROC curves for muscularis propria invasion and lymph node involvement showed no differences in diagnostic accuracy. The mean area under the ROC curve for endorectal sonography (A z = 0.996) for perirectal tissue invasion, however, showed higher accuracy than that of MRI (Az = 0.938, p = 0.028). CONCLUSION. The sensitivity, specificity, and accuracy of 3-T MRI were similar to those of endorectal sonography for muscularis propria invasion and lymph node involvement, but for perirectal tissue invasion, 3-T MRI was less accurate than endorectal sonography.

KW - Colon

KW - MRI

KW - Rectal cancer

KW - Sonography

UR - http://www.scopus.com/inward/record.url?scp=33751234550&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33751234550&partnerID=8YFLogxK

U2 - 10.2214/AJR.05.1234

DO - 10.2214/AJR.05.1234

M3 - Article

VL - 187

SP - 1557

EP - 1562

JO - American Journal of Roentgenology

JF - American Journal of Roentgenology

SN - 0361-803X

IS - 6

ER -