Preparation and characterization of a polar milk lipid-enriched component from whey powder

Kwanhyoung Lee, Ara Kim, Ki Bae Hong, Hyung Joo Suh, Kyungae Jo

Research output: Contribution to journalArticle

Abstract

Milk fat globule membrane (MFGM) is a lipid carrier in mammals including humans that consists mainly of polar lipids, like phospholipids and glycolipids. In this study, a process to enrich polar lipids in commercial butter and whey powder, including polar lipids of MFGM, was developed. WPC (whey protein concentrate) 60 was selected as the most suitable raw material based on the yield, phospholipid, protein, and lactose content of the polar lipid fraction obtained by ethanol extraction of two WPC (WPC60 and WPC70) and two buttermilk (A and B). After fractionation under optimum conditions, the polar-lipid enriched fraction from WPC60 contained 38.56% phospholipids. The content of glycolipids, cerebroside, lactosylceramide, ganglioside GM3, ganglioside GD3, was 0.97%, 0.55%, 0.09%, and 0.14%, respectively. Rancimat results showed that the oxidation stability of fish oil increased with an increase in the polar-lipid fraction by more than 30 times. In addition, the secretion of IL-6 and TNF-α decreased in a concentration-dependent manner after treatment of RAW 264.7 cells with 0.1 to 100 ppm of the polar lipid fraction. In this study, polar lipid concentrates with antioxidant and anti-inflammatory activity, were prepared from milk processing by-products. The MFGM polar lipid concentrates made from by-products are not only additives for infants, but are also likely to be used as antioxidants in cooking oils and as active ingredients for functional foods.

Original languageEnglish
Pages (from-to)209-220
Number of pages12
JournalFood Science of Animal Resources
Volume40
Issue number2
DOIs
Publication statusPublished - 2020 Mar

Keywords

  • Anti-inflammatory
  • Milk fat globule membrane (MFGM)
  • Polar lipids
  • Rancimat
  • Whey powder

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Food Science

Fingerprint Dive into the research topics of 'Preparation and characterization of a polar milk lipid-enriched component from whey powder'. Together they form a unique fingerprint.

  • Cite this