Preparation of alginate/chitosan/carboxymethyl chitosan complex microcapsules and application in Lactobacillus casei ATCC 393

Xiao Yan Li, Xi Guang Chen, Zhong Wu Sun, Hyun Jin Park, Dong Su Cha

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Lactobacillus casei ATCC 393 was encapsulated with alginate, chitosan and carboxymethyl chitosan by extrusion method and the product could increase the cell numbers of L. casei to be 108 cfu/g in the dry state after storage at 4 °C for 4 weeks. After incubation in simulated gastric (pH 2.0, 2 h) and bile juices (1%, 6 h), the encapsulated L. casei cell numbers were 7.91 and 7.42 log cfu/g, respectively. Results indicated that alginate-chitosan- carboxymethyl chitosan microcapsules could successfully protect L. casei against adverse conditions and this approach might be useful in the delivery of probiotic cultures as a functional food.

Original languageEnglish
Pages (from-to)1479-1485
Number of pages7
JournalCarbohydrate Polymers
Issue number4
Publication statusPublished - 2011 Feb 1



  • Carboxymethyl chitosan
  • Chitosan
  • Lactobacillus casei ATCC 393
  • Microcapsule
  • Sodium alginate
  • Survival

ASJC Scopus subject areas

  • Organic Chemistry
  • Materials Chemistry
  • Polymers and Plastics

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