Preparations of bicycliclactols from allyl and/or homoallyl propargyl acetal-cobalt complexes and its application to the formal synthesis of (±) loganine

Nakcheol Jeong, Yeoul Lee Bun, Min Lee Seong, Keun Chung Young, Lee Sueg-Geun

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

3-oxa-2-alkoxy bicyclo [3,3,0]-oct-5-en-7-ones and 3-oxa-2-alkoxy bicyclo [4,3,0]-non-5-en-7-ones were efficiently prepared from the corresponding bis(allyl or homoallyl)propargyl acetal-cobalt complexes in the presence of trimethylamine N-oxide. This methodology was successfully applied to the formal synthesis of (±) loganine.

Original languageEnglish
Pages (from-to)4023-4026
Number of pages4
JournalTetrahedron Letters
Volume34
Issue number25
Publication statusPublished - 1993 Jun 18
Externally publishedYes

    Fingerprint

ASJC Scopus subject areas

  • Drug Discovery
  • Organic Chemistry
  • Biochemistry

Cite this