Presence of gonadotropin-releasing hormone mRNA in the rat olfactory piriform cortex

Wan Sung Choi, Myung Ok Kim, Byung Ju Lee, Jin Hyun Kim, Woong Sun, Jae Young Seong, Kyungjin Kim

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Gonadotropin releasing hormone (GnRH) neurons are known to be originated from the olfactory placode and to enter the forebrain regions during embryonic development. The present study aims to ascertain whether GnRH is locally expressed in the olfactory cortex. Northern blot hybridization and reverse transcription-polymerase chain reaction revealed that GnRH mRNA was present in the rat olfactory cortex as well as in the olfactory bulb. The predicted size of GnRH mRNA is similar to that detected in the hypothalamus. In situ hybridization histochemistry also showed that GnRH mRNA is highly concentrated in the olfactory piriform cortex. The present data indicate that GnRH is synthesized in the olfactory piriform cortex.

Original languageEnglish
Pages (from-to)148-151
Number of pages4
JournalBrain Research
Volume648
Issue number1
Publication statusPublished - 1994 Jun 13
Externally publishedYes

Fingerprint

Gonadotropin-Releasing Hormone
Messenger RNA
Olfactory Bulb
Prosencephalon
Northern Blotting
Hypothalamus
Reverse Transcription
Embryonic Development
In Situ Hybridization
Olfactory Cortex
Piriform Cortex
Neurons
Polymerase Chain Reaction

Keywords

  • Extrahypothalmus
  • GnRH mRNA
  • Olfactory piriform cortex

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology
  • Molecular Biology
  • Developmental Biology

Cite this

Choi, W. S., Kim, M. O., Lee, B. J., Kim, J. H., Sun, W., Seong, J. Y., & Kim, K. (1994). Presence of gonadotropin-releasing hormone mRNA in the rat olfactory piriform cortex. Brain Research, 648(1), 148-151.

Presence of gonadotropin-releasing hormone mRNA in the rat olfactory piriform cortex. / Choi, Wan Sung; Kim, Myung Ok; Lee, Byung Ju; Kim, Jin Hyun; Sun, Woong; Seong, Jae Young; Kim, Kyungjin.

In: Brain Research, Vol. 648, No. 1, 13.06.1994, p. 148-151.

Research output: Contribution to journalArticle

Choi, WS, Kim, MO, Lee, BJ, Kim, JH, Sun, W, Seong, JY & Kim, K 1994, 'Presence of gonadotropin-releasing hormone mRNA in the rat olfactory piriform cortex', Brain Research, vol. 648, no. 1, pp. 148-151.
Choi, Wan Sung ; Kim, Myung Ok ; Lee, Byung Ju ; Kim, Jin Hyun ; Sun, Woong ; Seong, Jae Young ; Kim, Kyungjin. / Presence of gonadotropin-releasing hormone mRNA in the rat olfactory piriform cortex. In: Brain Research. 1994 ; Vol. 648, No. 1. pp. 148-151.
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