Pressureless sintering and mechanical and biological properties of fluor-hydroxyapatite composites with zirconia

Hae Won Kim, Young Min Kong, Young Hag Koh, Hyoun Ee Kim, Hyun Man Kim, Jea Seung Ko

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

Fluor-hydroxyapatite (FHA) fabricated by a reaction between fluorapatite (FA) and hydroxyapatite (HA) was mixed with ZrO2 to produce FHA-ZrO2 composites. When the relative amount of FA to HA increased, the decomposition of the composite was decreased gradually because of the formation of thermally stable FHA solid solutions. With such suppression of decomposition, the FHA-ZrO2 composites retained fully densified bodies. As a result, significant enhancements in mechanical properties, such as hardness, flexural strength, and fracture toughness, were achieved as the relative amount of FA to HA increased. The highest values in strength and toughness were 220 MPa and 2.5 MPa·m1/2, respectively, with FHA-40 vol% ZrO2 composites. In vitro proliferation of osteoblast-like cells (MG63) on the composites showed behavior similar to that observed on pore HA and FHA. Alkaline phosphatase (ALP) activity of the growing cells (HOS) on the composites was slightly down-regulated compared with that on pure HA and FHA at prolonged periods.

Original languageEnglish
Pages (from-to)2019-2026
Number of pages8
JournalJournal of the American Ceramic Society
Volume86
Issue number12
DOIs
Publication statusPublished - 2003 Dec
Externally publishedYes

ASJC Scopus subject areas

  • Ceramics and Composites
  • Materials Chemistry

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