TY - JOUR
T1 - Prevalence and phylogenetic analysis of human enteric emerging viruses in porcine stool samples in the Republic of Korea
AU - Yeo, Daseul
AU - Hossain, Md Iqbal
AU - Jung, Soontag
AU - Wang, Zhaoqi
AU - Seo, Yeeun
AU - Woo, Seoyoung
AU - Park, Sunho
AU - Seo, Dong Joo
AU - Rhee, Min Suk
AU - Choi, Changsun
N1 - Funding Information:
This research was supported by a grant (17162MFDS034) from the Ministry of Food and Drug Safety in 2017-2019. YS was supported by the Chung-Ang University Graduate Research Scholarship in 2021.
Publisher Copyright:
Copyright © 2022 Yeo, Hossain, Jung, Wang, Seo, Woo, Park, Seo, Rhee and Choi.
PY - 2022/9/30
Y1 - 2022/9/30
N2 - Emerging infectious diseases (EID) in humans and animals are proving to be a serious health concern. This study investigated the prevalence of emerging or re-emerging human enteric viruses in porcine stools and swabs. Eleven enteric EID viruses were selected as target viruses for the current study and ranked based on their impact on public health and food safety: enterovirus (EV), hepatitis E virus, norovirus GI and GII, sapovirus (SaV), adenovirus (AdV), astrovirus, rotavirus, hepatitis A virus, aichivirus, and bocavirus. Using real-time RT-PCR or real-time PCR, EID viruses were detected in 129 (86.0%) of 150 samples. The most prevalent virus was EV, which was detected in 68.0% of samples, followed by AdV with a detection rate of 38.0%. In following sequencing and phylogenetic analyses, 33.0% (58/176) of the detected viruses were associated with human enteric EID viruses, including AdV-41, coxsackievirus-A2, echovirus-24, and SaV. Our results show that porcine stools frequently contain human enteric viruses, and that few porcine enteric viruses are genetically related to human enteric viruses. These findings suggest that enteric re-emerging or EID viruses could be zoonoses, and that continuous monitoring and further studies are needed to ensure an integrated “One Health” approach that aims to balance and optimize the health of humans, animals, and ecosystems.
AB - Emerging infectious diseases (EID) in humans and animals are proving to be a serious health concern. This study investigated the prevalence of emerging or re-emerging human enteric viruses in porcine stools and swabs. Eleven enteric EID viruses were selected as target viruses for the current study and ranked based on their impact on public health and food safety: enterovirus (EV), hepatitis E virus, norovirus GI and GII, sapovirus (SaV), adenovirus (AdV), astrovirus, rotavirus, hepatitis A virus, aichivirus, and bocavirus. Using real-time RT-PCR or real-time PCR, EID viruses were detected in 129 (86.0%) of 150 samples. The most prevalent virus was EV, which was detected in 68.0% of samples, followed by AdV with a detection rate of 38.0%. In following sequencing and phylogenetic analyses, 33.0% (58/176) of the detected viruses were associated with human enteric EID viruses, including AdV-41, coxsackievirus-A2, echovirus-24, and SaV. Our results show that porcine stools frequently contain human enteric viruses, and that few porcine enteric viruses are genetically related to human enteric viruses. These findings suggest that enteric re-emerging or EID viruses could be zoonoses, and that continuous monitoring and further studies are needed to ensure an integrated “One Health” approach that aims to balance and optimize the health of humans, animals, and ecosystems.
KW - adenovirus
KW - emerging virus
KW - enteric virus
KW - enterovirus
KW - foodborne virus
KW - phylogenetic analysis
KW - pig
UR - http://www.scopus.com/inward/record.url?scp=85140957272&partnerID=8YFLogxK
U2 - 10.3389/fvets.2022.913622
DO - 10.3389/fvets.2022.913622
M3 - Article
AN - SCOPUS:85140957272
VL - 9
JO - Frontiers in Veterinary Science
JF - Frontiers in Veterinary Science
SN - 2297-1769
M1 - 913622
ER -
