Prevalence and risk factors of strabismus in children and adolescents in South Korea: Korea national health and nutrition examination survey, 2008 ± 2011

Kyung Eun Han, Seung Hee Baek, Seung Hyun Kim, Key Hwan Lim

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Purpose To evaluate the prevalence and risk factors associated with horizontal strabismus in children and adolescents in South Korea. Methods A total of 5,935 children and adolescents 5±18 years of age who participated in the fourth and fifth Korean National Health and Nutrition Examination Survey (KNHANES IV-V) from July 2008 to December 2011 were evaluated and the prevalence of horizontal strabismus was estimated. Univariate and multivariate logistic regression analyses were conducted to determine the association between demographic, socioeconomic and clinical risk factors and clinically significant exodeviation (>15 prism diopters [PD]) and esodeviation (> 10 PD). Results Among 5,935 eligible subjects, 84 subjects had clinically significant exodeviation and 13 had clinically significant esodeviation. The overall prevalence of clinically significant horizontal strabismus was 1.6% (95% confidence interval [CI], 1.2±2.1): 1.3% (95% CI, 1.0±1.7) for clinically significant exodeviation and 0.3% (95% CI, 0.1±0.6) for clinically significant esodeviation. Clinically significant exodeviation was associated with amblyopia (adjusted odds ratio [aOR], 6.45; 95% CI, 2.14±19.44), family history of strabismus (aOR, 4.91; 95% CI, 1.71±14.08) and astigmatism > 1.0 D (aOR, 1.84; 95% CI, 1.13±2.98). Clinically significant esodeviation was associated with hyperopia (aOR, 12.16; 95% CI, 1.31±113.04) and amblyopia (aOR, 4.70; 95% CI, 1.12±19.81). Other demographic, socioeconomic, and clinical variables were not associated with strabismus. Conclusion This study provides data on the prevalence and independent risk factors for clinically significant exodeviation and esodeviation in a representative population of children and adolescents in South Korea.

Original languageEnglish
Article numbere0191857
JournalPLoS One
Volume13
Issue number2
DOIs
Publication statusPublished - 2018 Feb 1

Fingerprint

Republic of Korea
National Health and Nutrition Examination Survey
Nutrition Surveys
Strabismus
South Korea
Korea
Nutrition
Korean Peninsula
confidence interval
Exotropia
Esotropia
risk factors
Health
Confidence Intervals
Prisms
odds ratio
Odds Ratio
Amblyopia
Logistics
socioeconomics

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Prevalence and risk factors of strabismus in children and adolescents in South Korea : Korea national health and nutrition examination survey, 2008 ± 2011. / Han, Kyung Eun; Baek, Seung Hee; Kim, Seung Hyun; Lim, Key Hwan.

In: PLoS One, Vol. 13, No. 2, e0191857, 01.02.2018.

Research output: Contribution to journalReview article

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title = "Prevalence and risk factors of strabismus in children and adolescents in South Korea: Korea national health and nutrition examination survey, 2008 ± 2011",
abstract = "Purpose To evaluate the prevalence and risk factors associated with horizontal strabismus in children and adolescents in South Korea. Methods A total of 5,935 children and adolescents 5±18 years of age who participated in the fourth and fifth Korean National Health and Nutrition Examination Survey (KNHANES IV-V) from July 2008 to December 2011 were evaluated and the prevalence of horizontal strabismus was estimated. Univariate and multivariate logistic regression analyses were conducted to determine the association between demographic, socioeconomic and clinical risk factors and clinically significant exodeviation (>15 prism diopters [PD]) and esodeviation (> 10 PD). Results Among 5,935 eligible subjects, 84 subjects had clinically significant exodeviation and 13 had clinically significant esodeviation. The overall prevalence of clinically significant horizontal strabismus was 1.6{\%} (95{\%} confidence interval [CI], 1.2±2.1): 1.3{\%} (95{\%} CI, 1.0±1.7) for clinically significant exodeviation and 0.3{\%} (95{\%} CI, 0.1±0.6) for clinically significant esodeviation. Clinically significant exodeviation was associated with amblyopia (adjusted odds ratio [aOR], 6.45; 95{\%} CI, 2.14±19.44), family history of strabismus (aOR, 4.91; 95{\%} CI, 1.71±14.08) and astigmatism > 1.0 D (aOR, 1.84; 95{\%} CI, 1.13±2.98). Clinically significant esodeviation was associated with hyperopia (aOR, 12.16; 95{\%} CI, 1.31±113.04) and amblyopia (aOR, 4.70; 95{\%} CI, 1.12±19.81). Other demographic, socioeconomic, and clinical variables were not associated with strabismus. Conclusion This study provides data on the prevalence and independent risk factors for clinically significant exodeviation and esodeviation in a representative population of children and adolescents in South Korea.",
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T1 - Prevalence and risk factors of strabismus in children and adolescents in South Korea

T2 - Korea national health and nutrition examination survey, 2008 ± 2011

AU - Han, Kyung Eun

AU - Baek, Seung Hee

AU - Kim, Seung Hyun

AU - Lim, Key Hwan

PY - 2018/2/1

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N2 - Purpose To evaluate the prevalence and risk factors associated with horizontal strabismus in children and adolescents in South Korea. Methods A total of 5,935 children and adolescents 5±18 years of age who participated in the fourth and fifth Korean National Health and Nutrition Examination Survey (KNHANES IV-V) from July 2008 to December 2011 were evaluated and the prevalence of horizontal strabismus was estimated. Univariate and multivariate logistic regression analyses were conducted to determine the association between demographic, socioeconomic and clinical risk factors and clinically significant exodeviation (>15 prism diopters [PD]) and esodeviation (> 10 PD). Results Among 5,935 eligible subjects, 84 subjects had clinically significant exodeviation and 13 had clinically significant esodeviation. The overall prevalence of clinically significant horizontal strabismus was 1.6% (95% confidence interval [CI], 1.2±2.1): 1.3% (95% CI, 1.0±1.7) for clinically significant exodeviation and 0.3% (95% CI, 0.1±0.6) for clinically significant esodeviation. Clinically significant exodeviation was associated with amblyopia (adjusted odds ratio [aOR], 6.45; 95% CI, 2.14±19.44), family history of strabismus (aOR, 4.91; 95% CI, 1.71±14.08) and astigmatism > 1.0 D (aOR, 1.84; 95% CI, 1.13±2.98). Clinically significant esodeviation was associated with hyperopia (aOR, 12.16; 95% CI, 1.31±113.04) and amblyopia (aOR, 4.70; 95% CI, 1.12±19.81). Other demographic, socioeconomic, and clinical variables were not associated with strabismus. Conclusion This study provides data on the prevalence and independent risk factors for clinically significant exodeviation and esodeviation in a representative population of children and adolescents in South Korea.

AB - Purpose To evaluate the prevalence and risk factors associated with horizontal strabismus in children and adolescents in South Korea. Methods A total of 5,935 children and adolescents 5±18 years of age who participated in the fourth and fifth Korean National Health and Nutrition Examination Survey (KNHANES IV-V) from July 2008 to December 2011 were evaluated and the prevalence of horizontal strabismus was estimated. Univariate and multivariate logistic regression analyses were conducted to determine the association between demographic, socioeconomic and clinical risk factors and clinically significant exodeviation (>15 prism diopters [PD]) and esodeviation (> 10 PD). Results Among 5,935 eligible subjects, 84 subjects had clinically significant exodeviation and 13 had clinically significant esodeviation. The overall prevalence of clinically significant horizontal strabismus was 1.6% (95% confidence interval [CI], 1.2±2.1): 1.3% (95% CI, 1.0±1.7) for clinically significant exodeviation and 0.3% (95% CI, 0.1±0.6) for clinically significant esodeviation. Clinically significant exodeviation was associated with amblyopia (adjusted odds ratio [aOR], 6.45; 95% CI, 2.14±19.44), family history of strabismus (aOR, 4.91; 95% CI, 1.71±14.08) and astigmatism > 1.0 D (aOR, 1.84; 95% CI, 1.13±2.98). Clinically significant esodeviation was associated with hyperopia (aOR, 12.16; 95% CI, 1.31±113.04) and amblyopia (aOR, 4.70; 95% CI, 1.12±19.81). Other demographic, socioeconomic, and clinical variables were not associated with strabismus. Conclusion This study provides data on the prevalence and independent risk factors for clinically significant exodeviation and esodeviation in a representative population of children and adolescents in South Korea.

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