Prevalence of fungal infection on foot in diabetic patients and correlation between diabetic ulcer and fungal infection on foot

Kwang Hoon Lee, Ju Hee Lee, Jeong Deuk Lee, Baik Kee Cho, Hyung Ok Kim, Kea Jeung Kim, Nack In Kim, Hae Jun Song, Sook Ja Son, Sang Won Kim, Chul Jong Park, Ki Ho Kim, Kyung Sool Kwon, Wook Hwa Park, Eil Soo Lee, Dae Gyoo Byun, Jin Wou Kim, Si Yong Kim, Jong Suk Lee, Won Hyoung Kang & 13 others Seok Don Park, Eung Ho Choi, Ai Young Lee, Jun Young Lee, Jeong Hee Hahm, Sung Wook Park, Gwang Seong Choi, Young Ho Won, Seong Jun Seo, Byung In Ro, Kwang Joong Kim, Jong Min Kim, Hee Joon Yu

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Object: The purpose of this study was to determine the prevalence of fungal infection and ulcer on the feet of diabetic patients and the existence of correlation between ulcer and fungal infection. Methods: A total of 21,693 outpatients diagnosed as diabetes mellitus at the department of endocrinology of 32 hospitals were examined. The diabetic patients with foot problems were consulted to the department of dermatology. Physical examination and KOH preparation were performed. Results: 13,271 patients had certain kinds of foot problem, accounting for 61.2% of 21,693 diabetics examined. Of these, fungal foot disease were found in 10,403 that constituted 78.4% (48.0% of the entire diabetic population). Tinea pedis was the diagnosis in 6,496 (29.9%), onychomycosis in 7,783 (35.9%), and coexistence was in 3,883 (17.9%). Foot deformity was in 1,346 (6.2% of diabetics; 10.1% of foot disease), non-palpable pulse in 1,051 (4.8%; 7.9%), and foot ulcer was in 425 (2.0%; 3.2%), following in a descending order of frequency. Odds ratios for diabetic foot ulcer were 2. 5 in patients with the foot deformity, 1.6 with fungal foot disease and 2.2 with non-palpable pulse. Conversely, Odds ratios for fungal foot disease were 2.5 with foot deformity, and 1.6 with foot ulcer. A total of 5,486 patients paid a visit to the department of dermatology. Of these, 4,519 patients were diagnosed with fungal infection through physical examination and KOH smear by dermatologists. The population comprised of 2,272 males and 2,247 females, showing similar prevalence between sexes. However, age did have positive correlation regarding prevalence of fungal foot disease. The number of diabetic patients with toenail problems was 3,847 patients (70%) and onychomycosis was proven mycologically in 3,276. Onychomycosis of distal subungal type was the most common clinical finding, most frequently involving the great toenails. Abnormal skin findings of the foot were seen in 3,885(70.8%) and tinea pedis was found in 3,209 (58.5%), most commonly involving the soles. Conclusion: This study showed that fungal infection might be regarded as a risk factor of foot ulcer. Treatment of fungal infection in diabetic patients might prevent diabetic foot disease such as ulcer and reduce the disability, morbidity and mortality in diabetic patients.

Original languageEnglish
Pages (from-to)908-915
Number of pages8
JournalKorean Journal of Dermatology
Volume41
Issue number7
Publication statusPublished - 2003 Jul 1
Externally publishedYes

Fingerprint

Diabetic Foot
Mycoses
Foot Diseases
Ulcer
Foot
Foot Ulcer
Foot Deformities
Onychomycosis
Tinea Pedis
Nails
Dermatology
Physical Examination
Pulse
Odds Ratio
Endocrinology
Population
Diabetes Mellitus
Outpatients
Morbidity
Skin

Keywords

  • Diabetes mellit
  • Foot ulcer
  • Fungal infection

ASJC Scopus subject areas

  • Dermatology

Cite this

Lee, K. H., Lee, J. H., Lee, J. D., Cho, B. K., Kim, H. O., Kim, K. J., ... Yu, H. J. (2003). Prevalence of fungal infection on foot in diabetic patients and correlation between diabetic ulcer and fungal infection on foot. Korean Journal of Dermatology, 41(7), 908-915.

Prevalence of fungal infection on foot in diabetic patients and correlation between diabetic ulcer and fungal infection on foot. / Lee, Kwang Hoon; Lee, Ju Hee; Lee, Jeong Deuk; Cho, Baik Kee; Kim, Hyung Ok; Kim, Kea Jeung; Kim, Nack In; Song, Hae Jun; Son, Sook Ja; Kim, Sang Won; Park, Chul Jong; Kim, Ki Ho; Kwon, Kyung Sool; Park, Wook Hwa; Lee, Eil Soo; Byun, Dae Gyoo; Kim, Jin Wou; Kim, Si Yong; Lee, Jong Suk; Kang, Won Hyoung; Park, Seok Don; Choi, Eung Ho; Lee, Ai Young; Lee, Jun Young; Hahm, Jeong Hee; Park, Sung Wook; Choi, Gwang Seong; Won, Young Ho; Seo, Seong Jun; Ro, Byung In; Kim, Kwang Joong; Kim, Jong Min; Yu, Hee Joon.

In: Korean Journal of Dermatology, Vol. 41, No. 7, 01.07.2003, p. 908-915.

Research output: Contribution to journalArticle

Lee, KH, Lee, JH, Lee, JD, Cho, BK, Kim, HO, Kim, KJ, Kim, NI, Song, HJ, Son, SJ, Kim, SW, Park, CJ, Kim, KH, Kwon, KS, Park, WH, Lee, ES, Byun, DG, Kim, JW, Kim, SY, Lee, JS, Kang, WH, Park, SD, Choi, EH, Lee, AY, Lee, JY, Hahm, JH, Park, SW, Choi, GS, Won, YH, Seo, SJ, Ro, BI, Kim, KJ, Kim, JM & Yu, HJ 2003, 'Prevalence of fungal infection on foot in diabetic patients and correlation between diabetic ulcer and fungal infection on foot', Korean Journal of Dermatology, vol. 41, no. 7, pp. 908-915.
Lee, Kwang Hoon ; Lee, Ju Hee ; Lee, Jeong Deuk ; Cho, Baik Kee ; Kim, Hyung Ok ; Kim, Kea Jeung ; Kim, Nack In ; Song, Hae Jun ; Son, Sook Ja ; Kim, Sang Won ; Park, Chul Jong ; Kim, Ki Ho ; Kwon, Kyung Sool ; Park, Wook Hwa ; Lee, Eil Soo ; Byun, Dae Gyoo ; Kim, Jin Wou ; Kim, Si Yong ; Lee, Jong Suk ; Kang, Won Hyoung ; Park, Seok Don ; Choi, Eung Ho ; Lee, Ai Young ; Lee, Jun Young ; Hahm, Jeong Hee ; Park, Sung Wook ; Choi, Gwang Seong ; Won, Young Ho ; Seo, Seong Jun ; Ro, Byung In ; Kim, Kwang Joong ; Kim, Jong Min ; Yu, Hee Joon. / Prevalence of fungal infection on foot in diabetic patients and correlation between diabetic ulcer and fungal infection on foot. In: Korean Journal of Dermatology. 2003 ; Vol. 41, No. 7. pp. 908-915.
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abstract = "Object: The purpose of this study was to determine the prevalence of fungal infection and ulcer on the feet of diabetic patients and the existence of correlation between ulcer and fungal infection. Methods: A total of 21,693 outpatients diagnosed as diabetes mellitus at the department of endocrinology of 32 hospitals were examined. The diabetic patients with foot problems were consulted to the department of dermatology. Physical examination and KOH preparation were performed. Results: 13,271 patients had certain kinds of foot problem, accounting for 61.2{\%} of 21,693 diabetics examined. Of these, fungal foot disease were found in 10,403 that constituted 78.4{\%} (48.0{\%} of the entire diabetic population). Tinea pedis was the diagnosis in 6,496 (29.9{\%}), onychomycosis in 7,783 (35.9{\%}), and coexistence was in 3,883 (17.9{\%}). Foot deformity was in 1,346 (6.2{\%} of diabetics; 10.1{\%} of foot disease), non-palpable pulse in 1,051 (4.8{\%}; 7.9{\%}), and foot ulcer was in 425 (2.0{\%}; 3.2{\%}), following in a descending order of frequency. Odds ratios for diabetic foot ulcer were 2. 5 in patients with the foot deformity, 1.6 with fungal foot disease and 2.2 with non-palpable pulse. Conversely, Odds ratios for fungal foot disease were 2.5 with foot deformity, and 1.6 with foot ulcer. A total of 5,486 patients paid a visit to the department of dermatology. Of these, 4,519 patients were diagnosed with fungal infection through physical examination and KOH smear by dermatologists. The population comprised of 2,272 males and 2,247 females, showing similar prevalence between sexes. However, age did have positive correlation regarding prevalence of fungal foot disease. The number of diabetic patients with toenail problems was 3,847 patients (70{\%}) and onychomycosis was proven mycologically in 3,276. Onychomycosis of distal subungal type was the most common clinical finding, most frequently involving the great toenails. Abnormal skin findings of the foot were seen in 3,885(70.8{\%}) and tinea pedis was found in 3,209 (58.5{\%}), most commonly involving the soles. Conclusion: This study showed that fungal infection might be regarded as a risk factor of foot ulcer. Treatment of fungal infection in diabetic patients might prevent diabetic foot disease such as ulcer and reduce the disability, morbidity and mortality in diabetic patients.",
keywords = "Diabetes mellit, Foot ulcer, Fungal infection",
author = "Lee, {Kwang Hoon} and Lee, {Ju Hee} and Lee, {Jeong Deuk} and Cho, {Baik Kee} and Kim, {Hyung Ok} and Kim, {Kea Jeung} and Kim, {Nack In} and Song, {Hae Jun} and Son, {Sook Ja} and Kim, {Sang Won} and Park, {Chul Jong} and Kim, {Ki Ho} and Kwon, {Kyung Sool} and Park, {Wook Hwa} and Lee, {Eil Soo} and Byun, {Dae Gyoo} and Kim, {Jin Wou} and Kim, {Si Yong} and Lee, {Jong Suk} and Kang, {Won Hyoung} and Park, {Seok Don} and Choi, {Eung Ho} and Lee, {Ai Young} and Lee, {Jun Young} and Hahm, {Jeong Hee} and Park, {Sung Wook} and Choi, {Gwang Seong} and Won, {Young Ho} and Seo, {Seong Jun} and Ro, {Byung In} and Kim, {Kwang Joong} and Kim, {Jong Min} and Yu, {Hee Joon}",
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TY - JOUR

T1 - Prevalence of fungal infection on foot in diabetic patients and correlation between diabetic ulcer and fungal infection on foot

AU - Lee, Kwang Hoon

AU - Lee, Ju Hee

AU - Lee, Jeong Deuk

AU - Cho, Baik Kee

AU - Kim, Hyung Ok

AU - Kim, Kea Jeung

AU - Kim, Nack In

AU - Song, Hae Jun

AU - Son, Sook Ja

AU - Kim, Sang Won

AU - Park, Chul Jong

AU - Kim, Ki Ho

AU - Kwon, Kyung Sool

AU - Park, Wook Hwa

AU - Lee, Eil Soo

AU - Byun, Dae Gyoo

AU - Kim, Jin Wou

AU - Kim, Si Yong

AU - Lee, Jong Suk

AU - Kang, Won Hyoung

AU - Park, Seok Don

AU - Choi, Eung Ho

AU - Lee, Ai Young

AU - Lee, Jun Young

AU - Hahm, Jeong Hee

AU - Park, Sung Wook

AU - Choi, Gwang Seong

AU - Won, Young Ho

AU - Seo, Seong Jun

AU - Ro, Byung In

AU - Kim, Kwang Joong

AU - Kim, Jong Min

AU - Yu, Hee Joon

PY - 2003/7/1

Y1 - 2003/7/1

N2 - Object: The purpose of this study was to determine the prevalence of fungal infection and ulcer on the feet of diabetic patients and the existence of correlation between ulcer and fungal infection. Methods: A total of 21,693 outpatients diagnosed as diabetes mellitus at the department of endocrinology of 32 hospitals were examined. The diabetic patients with foot problems were consulted to the department of dermatology. Physical examination and KOH preparation were performed. Results: 13,271 patients had certain kinds of foot problem, accounting for 61.2% of 21,693 diabetics examined. Of these, fungal foot disease were found in 10,403 that constituted 78.4% (48.0% of the entire diabetic population). Tinea pedis was the diagnosis in 6,496 (29.9%), onychomycosis in 7,783 (35.9%), and coexistence was in 3,883 (17.9%). Foot deformity was in 1,346 (6.2% of diabetics; 10.1% of foot disease), non-palpable pulse in 1,051 (4.8%; 7.9%), and foot ulcer was in 425 (2.0%; 3.2%), following in a descending order of frequency. Odds ratios for diabetic foot ulcer were 2. 5 in patients with the foot deformity, 1.6 with fungal foot disease and 2.2 with non-palpable pulse. Conversely, Odds ratios for fungal foot disease were 2.5 with foot deformity, and 1.6 with foot ulcer. A total of 5,486 patients paid a visit to the department of dermatology. Of these, 4,519 patients were diagnosed with fungal infection through physical examination and KOH smear by dermatologists. The population comprised of 2,272 males and 2,247 females, showing similar prevalence between sexes. However, age did have positive correlation regarding prevalence of fungal foot disease. The number of diabetic patients with toenail problems was 3,847 patients (70%) and onychomycosis was proven mycologically in 3,276. Onychomycosis of distal subungal type was the most common clinical finding, most frequently involving the great toenails. Abnormal skin findings of the foot were seen in 3,885(70.8%) and tinea pedis was found in 3,209 (58.5%), most commonly involving the soles. Conclusion: This study showed that fungal infection might be regarded as a risk factor of foot ulcer. Treatment of fungal infection in diabetic patients might prevent diabetic foot disease such as ulcer and reduce the disability, morbidity and mortality in diabetic patients.

AB - Object: The purpose of this study was to determine the prevalence of fungal infection and ulcer on the feet of diabetic patients and the existence of correlation between ulcer and fungal infection. Methods: A total of 21,693 outpatients diagnosed as diabetes mellitus at the department of endocrinology of 32 hospitals were examined. The diabetic patients with foot problems were consulted to the department of dermatology. Physical examination and KOH preparation were performed. Results: 13,271 patients had certain kinds of foot problem, accounting for 61.2% of 21,693 diabetics examined. Of these, fungal foot disease were found in 10,403 that constituted 78.4% (48.0% of the entire diabetic population). Tinea pedis was the diagnosis in 6,496 (29.9%), onychomycosis in 7,783 (35.9%), and coexistence was in 3,883 (17.9%). Foot deformity was in 1,346 (6.2% of diabetics; 10.1% of foot disease), non-palpable pulse in 1,051 (4.8%; 7.9%), and foot ulcer was in 425 (2.0%; 3.2%), following in a descending order of frequency. Odds ratios for diabetic foot ulcer were 2. 5 in patients with the foot deformity, 1.6 with fungal foot disease and 2.2 with non-palpable pulse. Conversely, Odds ratios for fungal foot disease were 2.5 with foot deformity, and 1.6 with foot ulcer. A total of 5,486 patients paid a visit to the department of dermatology. Of these, 4,519 patients were diagnosed with fungal infection through physical examination and KOH smear by dermatologists. The population comprised of 2,272 males and 2,247 females, showing similar prevalence between sexes. However, age did have positive correlation regarding prevalence of fungal foot disease. The number of diabetic patients with toenail problems was 3,847 patients (70%) and onychomycosis was proven mycologically in 3,276. Onychomycosis of distal subungal type was the most common clinical finding, most frequently involving the great toenails. Abnormal skin findings of the foot were seen in 3,885(70.8%) and tinea pedis was found in 3,209 (58.5%), most commonly involving the soles. Conclusion: This study showed that fungal infection might be regarded as a risk factor of foot ulcer. Treatment of fungal infection in diabetic patients might prevent diabetic foot disease such as ulcer and reduce the disability, morbidity and mortality in diabetic patients.

KW - Diabetes mellit

KW - Foot ulcer

KW - Fungal infection

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