Abstract
Objectives: It has been suggested that there is a strong association between sleep-disordered breathing (SDB) and stroke. However, this connection has not been studied in Korean subjects. Methods: Sixty-one patients with acute cerebral infarction (ACI) and 13 patients with transient ischemic attack (TIA) were consecutively enrolled. SDB was evaluated within 48 h of stroke or TIA onset using a portable screening device, which allowed incidents of apnea, hypopnea, and snoring to be automatically analyzed. Clinical and sleep-related variables, including body mass indices (BMI), cardiovascular risk factors, stroke severity and disability, and Epworth sleepiness scale, Stanford sleepiness scale, and Berlin questionnaire scores were assessed. Sixty-four age-matched patient's spouses or family members with no history of physician-diagnosed stroke were enrolled as controls. Results: Mean apnea-hypopnea index (AHI) was significantly higher in TIA (14.6±10.4) and ACI (15.6±14.7) patients than in the controls (7.8±7.0; p=0.001). The prevalences of SDB were 69.2% in TIA and 50.8% in ACI patients and 32.8% in controls. BMI and systolic blood pressure (SBP) were significantly higher in patients with SDB than in patients without SDB. Sleep-related stroke onset occurred in 17 patients (22.9%), and these patients had significantly higher AHIs. Multiple logistic regression analysis showed that BMI (odds ratio, 1.293; p=0.027) and SBP (odds ratio, 1.030; p=0.004) were found to independently predict SDB in patients with TIA or ACI. Conclusions: SDB is prevalent during the 48 h following ACI or TIA in Korean subjects. The authors recommend that SDB be evaluated after an ACI or TIA, especially in those with a high BMI and an elevated SBP.
| Original language | English |
|---|---|
| Pages (from-to) | 77-82 |
| Number of pages | 6 |
| Journal | Sleep and Breathing |
| Volume | 15 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2011 Jan 1 |
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Keywords
- Acute ischemic stroke
- Portable sleep apnea monitoring device
- Prevalence
- Sleep-disordered breathing
ASJC Scopus subject areas
- Otorhinolaryngology
- Clinical Neurology
Cite this
Prevalence of sleep-disordered breathing in acute ischemic stroke as determined using a portable sleep apnea monitoring device in Korean subjects. / Joo, Byung Euk; Seok, Hung Youl; Yu, Sungwook; Kim, Byung Jo; Park, Kun Woo; Lee, Dae Hie; Jung, Ki Young.
In: Sleep and Breathing, Vol. 15, No. 1, 01.01.2011, p. 77-82.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prevalence of sleep-disordered breathing in acute ischemic stroke as determined using a portable sleep apnea monitoring device in Korean subjects
AU - Joo, Byung Euk
AU - Seok, Hung Youl
AU - Yu, Sungwook
AU - Kim, Byung Jo
AU - Park, Kun Woo
AU - Lee, Dae Hie
AU - Jung, Ki Young
PY - 2011/1/1
Y1 - 2011/1/1
N2 - Objectives: It has been suggested that there is a strong association between sleep-disordered breathing (SDB) and stroke. However, this connection has not been studied in Korean subjects. Methods: Sixty-one patients with acute cerebral infarction (ACI) and 13 patients with transient ischemic attack (TIA) were consecutively enrolled. SDB was evaluated within 48 h of stroke or TIA onset using a portable screening device, which allowed incidents of apnea, hypopnea, and snoring to be automatically analyzed. Clinical and sleep-related variables, including body mass indices (BMI), cardiovascular risk factors, stroke severity and disability, and Epworth sleepiness scale, Stanford sleepiness scale, and Berlin questionnaire scores were assessed. Sixty-four age-matched patient's spouses or family members with no history of physician-diagnosed stroke were enrolled as controls. Results: Mean apnea-hypopnea index (AHI) was significantly higher in TIA (14.6±10.4) and ACI (15.6±14.7) patients than in the controls (7.8±7.0; p=0.001). The prevalences of SDB were 69.2% in TIA and 50.8% in ACI patients and 32.8% in controls. BMI and systolic blood pressure (SBP) were significantly higher in patients with SDB than in patients without SDB. Sleep-related stroke onset occurred in 17 patients (22.9%), and these patients had significantly higher AHIs. Multiple logistic regression analysis showed that BMI (odds ratio, 1.293; p=0.027) and SBP (odds ratio, 1.030; p=0.004) were found to independently predict SDB in patients with TIA or ACI. Conclusions: SDB is prevalent during the 48 h following ACI or TIA in Korean subjects. The authors recommend that SDB be evaluated after an ACI or TIA, especially in those with a high BMI and an elevated SBP.
AB - Objectives: It has been suggested that there is a strong association between sleep-disordered breathing (SDB) and stroke. However, this connection has not been studied in Korean subjects. Methods: Sixty-one patients with acute cerebral infarction (ACI) and 13 patients with transient ischemic attack (TIA) were consecutively enrolled. SDB was evaluated within 48 h of stroke or TIA onset using a portable screening device, which allowed incidents of apnea, hypopnea, and snoring to be automatically analyzed. Clinical and sleep-related variables, including body mass indices (BMI), cardiovascular risk factors, stroke severity and disability, and Epworth sleepiness scale, Stanford sleepiness scale, and Berlin questionnaire scores were assessed. Sixty-four age-matched patient's spouses or family members with no history of physician-diagnosed stroke were enrolled as controls. Results: Mean apnea-hypopnea index (AHI) was significantly higher in TIA (14.6±10.4) and ACI (15.6±14.7) patients than in the controls (7.8±7.0; p=0.001). The prevalences of SDB were 69.2% in TIA and 50.8% in ACI patients and 32.8% in controls. BMI and systolic blood pressure (SBP) were significantly higher in patients with SDB than in patients without SDB. Sleep-related stroke onset occurred in 17 patients (22.9%), and these patients had significantly higher AHIs. Multiple logistic regression analysis showed that BMI (odds ratio, 1.293; p=0.027) and SBP (odds ratio, 1.030; p=0.004) were found to independently predict SDB in patients with TIA or ACI. Conclusions: SDB is prevalent during the 48 h following ACI or TIA in Korean subjects. The authors recommend that SDB be evaluated after an ACI or TIA, especially in those with a high BMI and an elevated SBP.
KW - Acute ischemic stroke
KW - Portable sleep apnea monitoring device
KW - Prevalence
KW - Sleep-disordered breathing
UR - http://www.scopus.com/inward/record.url?scp=79958138956&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79958138956&partnerID=8YFLogxK
U2 - 10.1007/s11325-009-0325-8
DO - 10.1007/s11325-009-0325-8
M3 - Article
C2 - 20094807
AN - SCOPUS:79958138956
VL - 15
SP - 77
EP - 82
JO - Sleep and Breathing
JF - Sleep and Breathing
SN - 1520-9512
IS - 1
ER -