Prevalence of sleep-disordered breathing in acute ischemic stroke as determined using a portable sleep apnea monitoring device in Korean subjects

Byung Euk Joo, Hung Youl Seok, Sungwook Yu, Byung Jo Kim, Kun Woo Park, Dae Hie Lee, Ki Young Jung

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Objectives: It has been suggested that there is a strong association between sleep-disordered breathing (SDB) and stroke. However, this connection has not been studied in Korean subjects. Methods: Sixty-one patients with acute cerebral infarction (ACI) and 13 patients with transient ischemic attack (TIA) were consecutively enrolled. SDB was evaluated within 48 h of stroke or TIA onset using a portable screening device, which allowed incidents of apnea, hypopnea, and snoring to be automatically analyzed. Clinical and sleep-related variables, including body mass indices (BMI), cardiovascular risk factors, stroke severity and disability, and Epworth sleepiness scale, Stanford sleepiness scale, and Berlin questionnaire scores were assessed. Sixty-four age-matched patient's spouses or family members with no history of physician-diagnosed stroke were enrolled as controls. Results: Mean apnea-hypopnea index (AHI) was significantly higher in TIA (14.6±10.4) and ACI (15.6±14.7) patients than in the controls (7.8±7.0; p=0.001). The prevalences of SDB were 69.2% in TIA and 50.8% in ACI patients and 32.8% in controls. BMI and systolic blood pressure (SBP) were significantly higher in patients with SDB than in patients without SDB. Sleep-related stroke onset occurred in 17 patients (22.9%), and these patients had significantly higher AHIs. Multiple logistic regression analysis showed that BMI (odds ratio, 1.293; p=0.027) and SBP (odds ratio, 1.030; p=0.004) were found to independently predict SDB in patients with TIA or ACI. Conclusions: SDB is prevalent during the 48 h following ACI or TIA in Korean subjects. The authors recommend that SDB be evaluated after an ACI or TIA, especially in those with a high BMI and an elevated SBP.

Original languageEnglish
Pages (from-to)77-82
Number of pages6
JournalSleep and Breathing
Volume15
Issue number1
DOIs
Publication statusPublished - 2011 Jan 1

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Polysomnography
Sleep Apnea Syndromes
Transient Ischemic Attack
Stroke
Cerebral Infarction
Equipment and Supplies
Blood Pressure
Body Mass Index
Apnea
Sleep
Odds Ratio
Snoring
Berlin
Spouses
Logistic Models
Regression Analysis
Physicians

Keywords

  • Acute ischemic stroke
  • Portable sleep apnea monitoring device
  • Prevalence
  • Sleep-disordered breathing

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Clinical Neurology

Cite this

Prevalence of sleep-disordered breathing in acute ischemic stroke as determined using a portable sleep apnea monitoring device in Korean subjects. / Joo, Byung Euk; Seok, Hung Youl; Yu, Sungwook; Kim, Byung Jo; Park, Kun Woo; Lee, Dae Hie; Jung, Ki Young.

In: Sleep and Breathing, Vol. 15, No. 1, 01.01.2011, p. 77-82.

Research output: Contribution to journalArticle

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AU - Kim, Byung Jo

AU - Park, Kun Woo

AU - Lee, Dae Hie

AU - Jung, Ki Young

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