Prevalence of sleep-disordered breathing in acute ischemic stroke as determined using a portable sleep apnea monitoring device in Korean subjects

Byung Euk Joo, Hung Youl Seok, Sungwook Yu, Byung Jo Kim, Kun Woo Park, Dae Hie Lee, Ki Young Jung

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Objectives: It has been suggested that there is a strong association between sleep-disordered breathing (SDB) and stroke. However, this connection has not been studied in Korean subjects. Methods: Sixty-one patients with acute cerebral infarction (ACI) and 13 patients with transient ischemic attack (TIA) were consecutively enrolled. SDB was evaluated within 48 h of stroke or TIA onset using a portable screening device, which allowed incidents of apnea, hypopnea, and snoring to be automatically analyzed. Clinical and sleep-related variables, including body mass indices (BMI), cardiovascular risk factors, stroke severity and disability, and Epworth sleepiness scale, Stanford sleepiness scale, and Berlin questionnaire scores were assessed. Sixty-four age-matched patient's spouses or family members with no history of physician-diagnosed stroke were enrolled as controls. Results: Mean apnea-hypopnea index (AHI) was significantly higher in TIA (14.6±10.4) and ACI (15.6±14.7) patients than in the controls (7.8±7.0; p=0.001). The prevalences of SDB were 69.2% in TIA and 50.8% in ACI patients and 32.8% in controls. BMI and systolic blood pressure (SBP) were significantly higher in patients with SDB than in patients without SDB. Sleep-related stroke onset occurred in 17 patients (22.9%), and these patients had significantly higher AHIs. Multiple logistic regression analysis showed that BMI (odds ratio, 1.293; p=0.027) and SBP (odds ratio, 1.030; p=0.004) were found to independently predict SDB in patients with TIA or ACI. Conclusions: SDB is prevalent during the 48 h following ACI or TIA in Korean subjects. The authors recommend that SDB be evaluated after an ACI or TIA, especially in those with a high BMI and an elevated SBP.

Original languageEnglish
Pages (from-to)77-82
Number of pages6
JournalSleep and Breathing
Volume15
Issue number1
DOIs
Publication statusPublished - 2011 Jan 1

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Keywords

  • Acute ischemic stroke
  • Portable sleep apnea monitoring device
  • Prevalence
  • Sleep-disordered breathing

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Clinical Neurology

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