Prevalence of spirometrically-defined restrictive ventilatory defect in korea: The fourth-2, 3, and fifth korean national health and nutrition examination survey, 2008-2012

Jung Yeon Lee, Yong Il Hwang, Yong Bum Park, Jae Yong Park, Ki Uk Kim, Yeon Mok Oh, Hyoung Kyu Yoon, Ho Il Yoon, Sueng Su Sheen, Sang Yeub Lee, Chang Hoon Lee, Heung Bum Lee, Sung Chul Lim, Sung Soo Jung, Kyungwon Oh, Yuna Kim, Chaemin Chun, Kwang Ha Yoo

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9 Citations (Scopus)

Abstract

The aim of the study was to evaluate the prevalence of restrictive ventilatory defect and to determine the risk factors in subjects with spirometrically-defined restrictive ventilatory defect. We used the population-based, fourth-2, 3 (2008, 2009) and fifth (2010-2012) Korea National Health and Nutrition Examination Survey (KNHANES) to analyze 15,073 subjects, aged = 40 yr who underwent spirometry. Chest radiographs were also analyzed to identify restrictive lung disease. Spirometrically-defined restrictive ventilatory defect (FEV1/FVC = 70% and FVC < 80% of mean predicted value) was detected in 11.3% (n = 1,709) of subjects aged = 40 yr. The prevalence increased to 12.3% on using the lower limit of normal (LLN) criteria. Approximately 99.4% of subjects were classified as mild restrictive. Among these, 11.3% had inactive tuberculosis (TB) lesion, 2.2% cardiac disease, 2.0% previous operation scar or radiation injury and/or mediastinal disease, and 7.4% other pulmonary disease suggestive of restrictive lung diseases on chest radiograph. Evidence of previous TB history was independently associated with restrictive ventilatory defect (odds ratios [OR], 1.78; 95% confidence interval, 1.45-2.18) after adjustment for gender, age, smoking, area for residence and body mass index. The prevalence of restrictive ventilatory defect among the nationwide population in Korea was 11.3% with fixed ratio criterion and 12.3% with LLN criterion. Most cases were of the mild restrictive category and previous TB history is the independent risk factor for restrictive ventilatory defect.

Original languageEnglish
Pages (from-to)725-732
Number of pages8
JournalJournal of Korean medical science
Volume30
Issue number6
DOIs
Publication statusPublished - 2015

Keywords

  • Epidemiology
  • Lung diseases, interstitial
  • Respiratory function tests
  • Tuberculosis
  • X-rays

ASJC Scopus subject areas

  • Medicine(all)

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