Primary hepatic angiosarcoma

imaging findings and palliative treatment with transcatheter arterial chemoembolization or embolization

Yang Shin Park, J. H. Kim, K. W. Kim, I. S. Lee, H. K. Yoon, G. Y. Ko, K. B. Sung

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Aim: To describe the image findings and results of transcatheter arterial chemoembolization (TACE) or transcatheter arterial embolization (TAE) for treating primary hepatic angiosarcoma. Materials and methods: A retrospective review of the electronic medical database from 2002 to 2007, revealed six patients with primary hepatic angiosarcoma confirmed by percutaneous liver biopsy. The computed tomography (CT) and angiography imaging findings, the TACE or TAE results, and the post-procedure course were evaluated in all patients. Results: On CT and angiography, each tumour appeared as a solitary mass or as multiple nodules or masses with heterogeneously early and progressive enhancement. One of the two patients with tumour response to TACE died 8 months after initial presentation, and the remaining patient was still alive at the last follow-up 12 months after initial presentation. However, two patients with no response to TACE and two patients who underwent emergent TAE for tumour rupture died 1 week to 5 months (mean 2.1 months) after initial presentation. Conclusions: Primary hepatic angiosarcoma appears as a solitary or multiple, hypervascular lesions with heterogeneously early and progressive enhancement on CT and angiography. Although TAE may be the primary procedure for achieving emergent bleeding control caused by the rupture of hepatic angiosarcomas, TACE may be effective for treating patients with a dominant hepatic angiosarcoma with or without intrahepatic metastases.

Original languageEnglish
Pages (from-to)779-785
Number of pages7
JournalClinical Radiology
Volume64
Issue number8
DOIs
Publication statusPublished - 2009 Aug 1
Externally publishedYes

Fingerprint

Hemangiosarcoma
Palliative Care
Liver
Rupture
Medical Electronics
Neoplasms
Databases
Hemorrhage
Neoplasm Metastasis
Biopsy
Computed Tomography Angiography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Primary hepatic angiosarcoma : imaging findings and palliative treatment with transcatheter arterial chemoembolization or embolization. / Park, Yang Shin; Kim, J. H.; Kim, K. W.; Lee, I. S.; Yoon, H. K.; Ko, G. Y.; Sung, K. B.

In: Clinical Radiology, Vol. 64, No. 8, 01.08.2009, p. 779-785.

Research output: Contribution to journalArticle

Park, Yang Shin ; Kim, J. H. ; Kim, K. W. ; Lee, I. S. ; Yoon, H. K. ; Ko, G. Y. ; Sung, K. B. / Primary hepatic angiosarcoma : imaging findings and palliative treatment with transcatheter arterial chemoembolization or embolization. In: Clinical Radiology. 2009 ; Vol. 64, No. 8. pp. 779-785.
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