Primary hyperparathyroidism with extensive brown tumors and multiple fractures in a 20-year-old woman

Ju Hee Choi, Kyoung Jin Kim, Ye Jin Lee, Sun Hwa Kim, Sin Gon Kim, Kwang Yoon Jung, Dong Seop Choi, Nam Hoon Kim

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A brown tumor is a benign fibrotic, erosive bony lesion caused by localized, rapid osteoclastic turnover, resulting from hyperparathyroidism. Although brown tumors are one of the most pathognomonic signs of primary hyperparathyroidism, they are rarely seen in clinical practice. In this report, we present a case of 20-year-old woman with recurrent fractures and bone pain. Plain digital radiographs of the affected bones revealed multiple erosive bone tumors, which were finally diagnosed as brown tumors associated with primary hyperparathyroidism due to a parathyroid adenoma. This case shows that multiple, and clinically severe form of brown tumors can even occur in young patients.

    Original languageEnglish
    Pages (from-to)614-619
    Number of pages6
    JournalEndocrinology and Metabolism
    Volume30
    Issue number4
    DOIs
    Publication statusPublished - 2015

    Keywords

    • Brown tumor
    • Hyperparathyroidism
    • Parathyroid neoplasms

    ASJC Scopus subject areas

    • Endocrinology, Diabetes and Metabolism
    • Endocrinology

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