Primary hyperparathyroidism with extensive brown tumors and multiple fractures in a 20-year-old woman

Ju Hee Choi, Kyoung Jin Kim, Ye Jin Lee, Sun Hwa Kim, Sin Gon Kim, Kwang-Yoon Jung, Dong Seop Choi, Nam Hoon Kim

Research output: Contribution to journalArticle

Abstract

A brown tumor is a benign fibrotic, erosive bony lesion caused by localized, rapid osteoclastic turnover, resulting from hyperparathyroidism. Although brown tumors are one of the most pathognomonic signs of primary hyperparathyroidism, they are rarely seen in clinical practice. In this report, we present a case of 20-year-old woman with recurrent fractures and bone pain. Plain digital radiographs of the affected bones revealed multiple erosive bone tumors, which were finally diagnosed as brown tumors associated with primary hyperparathyroidism due to a parathyroid adenoma. This case shows that multiple, and clinically severe form of brown tumors can even occur in young patients.

Original languageEnglish
Pages (from-to)614-619
Number of pages6
JournalEndocrinology and Metabolism
Volume30
Issue number4
DOIs
Publication statusPublished - 2015 Jan 1

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Primary Hyperparathyroidism
Neoplasms
Bone and Bones
Parathyroid Neoplasms
Hyperparathyroidism
Bone Fractures
Multiple Fractures
Pain

Keywords

  • Brown tumor
  • Hyperparathyroidism
  • Parathyroid neoplasms

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Primary hyperparathyroidism with extensive brown tumors and multiple fractures in a 20-year-old woman. / Choi, Ju Hee; Kim, Kyoung Jin; Lee, Ye Jin; Kim, Sun Hwa; Kim, Sin Gon; Jung, Kwang-Yoon; Choi, Dong Seop; Kim, Nam Hoon.

In: Endocrinology and Metabolism, Vol. 30, No. 4, 01.01.2015, p. 614-619.

Research output: Contribution to journalArticle

Choi, Ju Hee ; Kim, Kyoung Jin ; Lee, Ye Jin ; Kim, Sun Hwa ; Kim, Sin Gon ; Jung, Kwang-Yoon ; Choi, Dong Seop ; Kim, Nam Hoon. / Primary hyperparathyroidism with extensive brown tumors and multiple fractures in a 20-year-old woman. In: Endocrinology and Metabolism. 2015 ; Vol. 30, No. 4. pp. 614-619.
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